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March 2009 — Alternative Medicine

Heart in hand

Alternative medicine has evolved and grown over the years – it’s not just a few supplementing herbal remedies for prescription drugs. It’s a widespread practice commonly referred to as complementary and alternative medicine (CAM) and integrative medicine. It combines conventional Western medicine with alternative or complementary treatments, such as herbal medicine, acupuncture, massage, and yoga.

According to a nationwide government survey released in December 2008, approximately 38 percent of U.S. adults aged 18 years and over, and approximately 12 percent of children use some form of CAM.

With Epocrates*, you can help ensure that your patients who are taking these medicines do so safely. We offer authoritative information on more than 600 complementary and alternative medicines including reported uses and doses, interactions with prescription drugs, adverse reactions, and more.

*Available with Epocrates Rx Pro®, Epocrates® Essentials, Epocrates® Essentials Deluxe mobile software and Epocrates Online Premium.

Also in this issue:

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Brought to you by Epocrates Online, featuring at-a-glance disease overviews, detailed diagnostic and treatment recommendations, and national medical society guidelines.

Purchase a Palm TX or HP iPAQ 210 and get two years of Epocrates software at a special discounted rate through March 31, 2009. This offer starts at $329, which is the lowest we have seen. It's perfect if you've been waiting to upgrade your old Palm device!

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DocAlert® Messages of the Month

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Integrative Medicine

Editorial: Dr. Anne Meneghetti, Internist, Epocrates' senior medical editor

Some patients are delighted to learn that a solution to their medical problem might be found in a pill. Other patients are not. Patients attracted to alternative medicine often seek to understand the root cause of their condition and perhaps even discover meaning on the path to self-healing. Many physicians are perplexed when patients choose to forego proven standardized therapies from licensed practitioners and instead forge ahead into the untested territory of natural healing.

Read Dr. Meneghetti's full editorial »

A randomised interventional trial of omega-3-polyunsaturated fatty acids on endothelial function and disease activity in systemic lupus erythematosus

Objective: To determine the clinical effect of dietary supplementation with low-dose omega-3-polyunsaturated fatty acids on disease activity and endothelial function in patients with systemic lupus erythematosus.

Read More »

Probiotics may improve irritable bowel syndrome

Bottom line: This systematic review/meta-analysis of randomized trials found a significant benefit of probiotics (number needed to treat [NNT] = 12) for improving symptoms of irritable bowel syndrome (IBS). Given the frequent difficulty in adequately treating this illness and the generally benign effects of probiotics, clinicians should strongly consider them for their patients with IBS. (LOE = 1a)

Read More »

Probiotics decrease antibiotic-associated diarrhea in children

Bottom line: A probiotic consisting of several strains of a Lactobacillus species is effective in preventing prolonged diarrhea (greater than 48 hours) in children receiving antibiotics. It did not decrease the likelihood of developing diarrhea related to Clostridium difficile, although the study may have been too small to detect a benefit if one exist. (LOE = 1a)

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Effect of fibre, antispasmodics, and peppermint oil in the treatment of irritable bowel syndrome: systematic review and meta-analysis

Results: 12 studies compared fibre with placebo or no treatment in 591 patients (relative risk of persistent symptoms 0.87, 95% confidence interval 0.76 to 1.00). This effect was limited to ispaghula (0.78, 0.63 to 0.96). Twenty-two trials compared antispasmodics with placebo in 1778 patients (0.68, 0.57 to 0.81). Various antispasmodics were studied, but otilonium (four trials, 435 patients, relative risk of persistent symptoms 0.55, 0.31 to 0.97) and hyoscine (three trials, 426 patients, 0.63, 0.51 to 0.78) showed consistent evidence of efficacy. Four trials compared peppermint oil with placebo in 392 patients (0.43, 0.32 to 0.59).

Read More »

FDA MedWatch Safety Alerts

PML Cases Associated With Use of Raptiva
Zonisamide May Cause Metabolic Acidosis
Ongoing Safety Review of Clopidogrel: Studies on Genetic Differences and PPI Effects

What's New With Epocrates

Acute Pain Management Mobile Resource Center

The Acute Pain Management Mobile Resource Center is now available as a FREE download. You’ll receive the most important and current clinical news and research on acute pain. The articles are carefully selected and commented upon by Perry G. Fine, M.D., Professor of Anesthesiology at the University of Utah School of Medicine.

And don’t forget! Mobile Resource Centers are also available for Leukemia, Hypertension, IBS & Chronic Constipation, Epilepsy, Allergy & Asthma, Diabetes, Chronic Pain Management, Fibromyalgia, ADHD, and Infection Management.

Mobile Resources Centers are available on Windows Mobile (Pocket PC) and Palm OS.

Wal-Mart’s $4 Generic Prescription Drug List Now Available!

Epocrates is happy to announce the addition of Walmart’s $4 generic drug program to its formulary hosting service. Before writing a prescription, prescribers can quickly check and compare the Walmart drug list using Epocrates to see if a less expensive alternative is available.

This can better equip healthcare professionals looking to identify lower cost medication options available for their patients at Walmart, Neighborhood Market and Sam’s Club pharmacies nationwide. With the program, customers can get up to a 30-day supply of more than 350 generic prescriptions for only $4 and a 90-day supply for $10.

Add this drug list »

Upcoming Meetings — Meet the Epocrates Team!

Pri-Med Midwest: March 5-7 — Rosemount, IL
American Academy of Dermatology: March 6-10 — San Francisco, CA

Updates at a Glance

New Disease and Condition Topics Available*

*This disease information can be found in Epocrates Online, Epocrates Online Premium or Epocrates Essentials for the iPhone.

New Drugs

MobileCME Headlines

  • Multiple Sclerosis: Therapeutic Immunomodulation
  • Pediatric GERD: The Current Word
  • RA Case Study (RAEC): Early Opportunity for Treatment

New Formularies

  • Mercy Health Plans 2-Tier (AR and MO)
  • Mercy Health Plans 4-Tier (AR and MO)
  • Walmart $4 Prescriptions (National)

How to Get these Updates

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Mobile: Update (sync) your device regularly to download free updates, including new drug monographs and MobileCME activities. If you don't have MobileCME, download it here. Add new formularies to your profile in My Account.

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Online: Log in to Epocrates Online for continually updated drug information and disease content. Select new formularies in the DRUGS tab.

Tech Tips

How to Install Epocrates Essentials for the iPhone

Are you looking to add Epocrates Essentials to your iPhone or iPod® touch? Just order through our site, enter your login information, and follow the instructions. It’ll only take about five minutes, but the benefits will last a lot longer than that!

Do you have other questions? Maybe you want to know if you can transfer your existing subscription? Maybe you already have Epocrates Rx and want to upgrade to Epocrates Essentials? We’re here to help! Please contact customer support with any additional questions.

And Finally...

We’re giving away three copies of the new reference book, How To Use Herbs, Nutrients, and Yoga in Mental Health Care by Drs. Richard P. Brown, Patricia L. Gerbarg, and Philip R. Muskin. To enter, tell us which herbal remedy was found to soothe IBS in a systematic study. [Hint: it’s referenced in the DocAlert messages above.]

Send Your Answer Now »

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