Epocrates Named One of The World's 50 Most Innovative Companies

Fast Company Recognizes Epocrates for Mobile Innovation That Helps Doctors Make the Best Decisions

San Mateo, Calif., March 2, 2011

Epocrates (NASDAQ: EPOC) today announced it was ranked tenth on the world's 50 Most Innovative Companies list in 2011 by Fast Company.

Epocrates was selected as one of the world's 50 Most Innovative Companies as a result of its mobile drug reference tools that allow "medical professionals to make smart prescribing decisions," and its planned mobile and web-based EHR system for solo and small group practice physicians. More than one million healthcare professionals, including more than 45 percent of U.S. physicians, actively use Epocrates products on mobile devices such as iPhone®/iPod® touch, Android™ , BlackBerry®, and Palm®.

"Epocrates focuses on innovation and changing the way physicians access information at the point of care," said Rose Crane, president and chief executive officer of Epocrates. "From developing the first mobile drug reference for the iPhone, to introducing our pioneering contact manufacturer service, to developing our planned physician-centric EHR solution, we continue to explore novel ways to meet physicians' needs. We are honored by this recognition from Fast Company."

Fast Company's editorial team evaluated information about thousands of businesses across the globe to create the world's 50 Most Innovative Companies issue. Other top ten companies include Apple, Facebook, and Google. Epocrates was also ranked one of the top ten Most Innovative Companies in the mobile industry.

"Innovation has never been more important to our economy and our future," said Fast Company Editor Robert Safian. "These companies embody what unleashing human potential can accomplish."

About Fast Company
Fast Company is the world's leading progressive business-media brand, with a unique editorial focus on innovation in technology, ethonomics (ethical economics), leadership, and design. Written for, by, and about the most progressive business leaders. Editor Robert Safian was named AdWeek's Editor of the Year in 2009. Under the leadership of publisher Christine Osekoski, Fast Company made AdWeek's Hot List for three consecutive years, and FastCompany.com executive editor Noah Robischon has tripled traffic and revenue year over year. Fast Company is owned by Joe Mansueto, founder and owner of Morningstar, a leading provider of independent investment research.

This press release contains forward-looking statements. Any statements contained in this press release that are not statements of historical fact may be deemed to be forward-looking statements. These forward-looking statements are based upon the company's current expectations. Actual results could differ materially from these forward-looking statements as a result of certain factors, including, risks detailed in Epocrates' filings with, the Securities and Exchange Commission (SEC), including in Epocrates' registration statement on Form S-1 dated February 1, 2011. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of this press release. Epocrates does not undertake any obligation to update any forward-looking statements as a result of new information, future events, changed assumptions or otherwise, and there can be no assurances that the company will continue to develop innovative products.

Media Contact

Holly Spring
athenahealth, Inc. (Media)

Dana Quattrochi
athenahealth, Inc. (Investors)

April Marks
Epocrates, Inc. (Media)