In general, children have lower incidences of SARS-CoV-2 infection, severe dz, & death compared w/ adults. Risk factors for severe dz include presence of ≥1 severe comorbidity such as medical complexity w/ respiratory technology dependence, neurologic condition resulting in impaired mucociliary clearance, obesity (esp severe obesity), severe underlying cardiac or pulmonary dz, & severe immunocompromise.

Generally, the older the child & the more severe the dz, the more reasonable it is to follow tx recs for adult pts w/ COVID-19.

No drug is authorized or approved for pre-exposure prophylaxis of COVID-19. CDC recommends that everyone ≥6 mo of age stay up-to-date w/ COVID-19 vaccination, including boosters, if eligible.

Consensus Guidelines for COVID-19 Drug Therapies in Adults