Guideline Resources
MIS-C Associated With COVID-19 | Emerging Guidance Synthesis
Key Points
Peds COVID-19 infxn remains relatively uncommon, usually mild, but multisystem syndrome, sharing characteristics of toxic shock, macrophage activation, and Kawasaki syndromes, continues to be defined and studied. Onset ~4wk post-infxn. Pts deteriorate rapidly (≥65% develop shock, all develop organ dysfxn). Isolated resp failure rare, cardiac dz most common.
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Based on multiple guidelines/recommendations from specialty societies/government agencies.
Epocrates Guideline Synopsis Last Update: Dec 8, 2020
Publication Year:
Ab antibody
Ag antigen
APLS Advanced Pediatric Life Support (AAP)
BCx blood culture
BNP B-type natriuretic peptide
CAA coronary artery aneurysm
CBC complete blood count
CDC Centers for Disease Control & Prevention
COVID-19 coronavirus disease 2019
CRP C-reactive protein
EKG electrocardiogram
ESR erythrocyte sedimentation rate
GI gastroenterology
ID infectious disease
IL-6 interleukin-6
IVIG intravenous immunoglobulin
LDH lactose dehydrogenase
LFT liver function test
lymphs lymphocytes
MIS-C multisystem inflammatory syndrome in children
neuts neutrophils
NT-pro-BNP N-terminal pro B-type natriuretic peptide
PALS Pediatric Advanced Life Support (AHA)
PICU pediatric intensive care unit
PIDS Pediatric Infectious Diseases Society
PPE personal protective equipment
PT prothrombin time
PTT partial thromboplastin time
RCPCH Royal College of Paediatrics and Child Health
RT-PCR reverse transcription polymerase chain reaction
SARS-CoV-2 Severe Acute Respiratory Syndrome Coronavirus 2
VS vital signs
WHO World Health Organization