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Tums
calcium carbonate
Uses .
- [ calcium carbonate ]
- antacid for relieving heartburn, upset stomach; calcium for dietary supplementation and reducing the risk of osteoporosis
Dosing .
dyspepsia
- [ 12 yo and older ]
- Dose: 2-4 tabs PO prn; Max: 15 tabs/24h; Info: max 10 tabs/24h if pregnant
osteoporosis prevention, postmenopausal (off-label)
- [ adults ]
- Dose: 2 tabs PO tid; Info: give with food
dietary supplementation (off-label)
- [ individualize dose ]
- Info: see Dietary Reference Intakes, Calcium table
renal dosing
- [ peds ]
- CrCl <25: consider dose adjustment based on calcium levels
- HD/PD: not defined
- [ adults ]
- renal impairment: no adjustment
- HD/PD: not defined
hepatic dosing
- [ not defined ]
Formulations .
chewable tablet
- [active ingredients per tab]
- calcium carbonate 500 mg (equivalent to 200 mg elemental Ca)
- [flavors/selected other ingredients]
- peppermint flavor contains sugar, no alcohol, no dye, no phenylalanine, no saccharin, no sucralose
Contraindications / Cautions .
- hypersensitivity to drug or ingredient
- hypercalcemia
- hypophosphatemia
- nephrolithiasis
- caution: hypercalciuria
- caution: dehydration
- caution: renal impairment
- caution: hyperparathyroidism
- caution: vitamin D toxicity
- caution: GI bleeding
- caution: GI obstruction
- caution: botulism
Drug Interactions .
Overview
calcium carbonate
calcium salt (antacid)
Interaction Characteristics:
- gastric pH modulator
- hypercalcemia
- hypophosphatemia
- polyvalent cation
- urine alkalinizer
Avoid/Use Alternative
- amphetamine
- baloxavir marboxil
- calcium acetate
- ciprofloxacin
- dextroamphetamine
- erdafitinib
- erlotinib
- lisdexamfetamine
- mefenamic acid
- mesalamine
- methamphetamine
- methenamine
- methylphenidate
- mexiletine
- nirogacestat
- potassium acid phosphate
- potassium phosphate
- raltegravir
- selpercatinib
- sodium acid phosphate
- sodium phosphate (supplement)
- sotorasib
- trientine
- ziftomenib
Monitor/Modify Tx
- abaloparatide
- alendronate
- aluminum hydroxide
- atazanavir
- bictegravir
- bisacodyl
- bosutinib
- burosumab
- cabotegravir
- calcipotriene topical
- calcitriol
- calcitriol topical
- calcium chloride
- calcium citrate
- calcium gluconate
- captopril
- cefpodoxime
- cefuroxime axetil
- chloroquine
- chlorothiazide
- chlorthalidone
- cholecalciferol (vitamin D3)
- cysteamine
- dasatinib
- defactinib
- deferiprone
- delafloxacin
- demeclocycline
- dicyclomine
- diflunisal
- digoxin
- dolutegravir
- domperidone
- doxercalciferol
- doxycycline
- eltrombopag
- elvitegravir
- ergocalciferol (vitamin D2)
- ethambutol
- flecainide
- fosinopril
- gefitinib
- glipizide
- hydrochlorothiazide
- hyoscyamine
- ibandronate
- indapamide
- itraconazole
- ketoconazole
- ledipasvir
- leucovorin
- levofloxacin
- levoketoconazole
- levothyroxine
- lithium
- magnesium carbonate
- magnesium hydroxide
- methscopolamine
- methyltestosterone
- metolazone
- minocycline
- mycophenolate mofetil
- naproxen
- neratinib
- nilotinib
- octreotide
- ofloxacin
- omadacycline
- palopegteriparatide
- paricalcitol
- pazopanib
- penicillamine
- pexidartinib
- phenytoin
- potassium citrate
- pseudoephedrine
- quinidine (antiarrhythmic)
- quinidine (CYP2D6 inhibitor)
- quinine
- rifampin
- rilpivirine
- rilzabrutinib
- risedronate
- sarecycline
- sodium bicarbonate
- sodium citrate
- sparsentan
- taletrectinib
- teriparatide
- testosterone
- tetracycline
- thyroid
- tipranavir
- triazolam
- vadadustat
- velpatasvir
Caution Advised
- amantadine
- belumosudil
- ferrous fumarate
- ferrous gluconate
- ferrous sulfate
- fosamprenavir
- lactulose
- memantine
- peppermint
- salsalate
- sodium polystyrene sulfonate
Adverse Reactions .
Serious Reactions
- hypercalcemia
- nephrolithiasis
- milk-alkali syndrome (prolonged high-dose use)
Common Reactions
- hypercalcemia
- hypercalciuria
- nephrolithiasis
- hypomagnesemia
- constipation
- nausea