Highlights & Basics
- Focal atrial tachycardia occurs in the settings of structurally normal heart, coronary artery disease, congestive heart failure, cardiac surgery, catecholamine ingestion, digoxin toxicity, and alcohol dependency.
- Symptoms and signs include palpitations, fatigue, presyncope/syncope, chest pain, and dyspnea.
- ECG shows a regular atrial tachycardia with P-wave morphology different from that in sinus tachycardia.
- A trial of adenosine can help differentiate focal AT from other supraventricular tachycardias.
- Initial therapy should be guided by cause, comorbid conditions, hemodynamic status, and patient preference. First-line options for hemodynamically stable patients include intravenous beta-blockers or calcium-channel blockers, or catheter ablation.
Quick Reference
History & Exam
Key Factors
Other Factors
Diagnostics Tests
Treatment Options
Definition
Epidemiology
Etiology
Pathophysiology
Images
Focal atrial tachycardia in an 88-year-old woman with 2:1 AV nodal block in the setting of digoxin therapy and potassium 2.8 mEq/L
Focal atrial tachycardia in a 35-year-old with history of recent cocaine use
ECG following cardioversion of focal atrial tachycardia in a 35-year-old with history of recent cocaine use
Focal atrial tachycardia in a 55-year-old with ischemic cardiomyopathy
Diagnostic algorithm for differentiating atrial tachycardias from other narrow QRS tachycardias. AV = atrioventricular, PAC = premature atrial contraction
Response to adenosine 6 mg intravenously
Citations
Page RL, Joglar JA, Caldwell MA, et al. 2015 ACC/AHA/HRS guideline for the management of adult patients with supraventricular tachycardia: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2016 Apr 5;67(13):e27-e115.[Abstract][Full Text]
Brugada J, Katritsis DG, Arbelo E, et al. 2019 ESC guidelines for the management of patients with supraventricular tachycardia. The Task Force for the management of patients with supraventricular tachycardia of the European Society of Cardiology (ESC). Eur Heart J. 2020 Feb 1;41(5):655-720.[Abstract][Full Text]
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12. Chauhan VS, Krahn GJ, Skanes AC, et al. Supraventricular tachycardia. Med Clin North Am. 2001 Mar;85(2):193-223, ix.[Abstract]
13. Innes JA. Review article: adenosine use in the emergency department. Emerg Med Australas. 2008 Jun;20(3):209-15.[Abstract]
14. Iwai S, Markowitz SM, Stein KM, et al. Response to adenosine differentiates focal from macroreentrant atrial tachycardia: validation using three-dimensional electroanatomic mapping. Circulation. 2002 Nov 26;106(22):2793-9.[Abstract][Full Text]
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16. Fox DJ, Tischenko A, Krahn AD, et al. Supraventricular tachycardia: diagnosis and management. Mayo Clin Proc. 2008 Dec;83(12):1400-11.[Abstract]
17. Engelstein ED, Lippman N, Stein KM, et al. Mechanism-specific effects of adenosine on atrial tachycardia. Circulation. 1994 Jun;89(6):2645-54.[Abstract]
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19. Antman EM, Wenger TL, Butler VP Jr, et al. Treatment of 150 cases of life-threatening digitalis intoxication with digoxin-specific Fab antibody fragments: final report of a multicenter study. Circulation. 1990 Jun;81(6):1744-52.[Abstract]
20. Perry J, Fenrich AL, Hulse JE, et al. Pediatric use of amiodarone: efficacy and safety in critically ill patients from a multicenter protocol. J Am Coll Cardiol. 1996 Apr;27(5):1246-50.[Abstract]
21. Ono K, Iwasaki YK, Akao M, et al. JCS/JHRS 2020 guideline on pharmacotherapy of cardiac arrhythmias. Circ J. 2022 Oct 25;86(11):1790-924.[Abstract][Full Text]
22. Nerheim P, Birger-Botkin S, Piracha L, et al. Heart failure and sudden death in patients with tachycardia-induced cardiomyopathy and recurrent tachycardia. Circulation. 2004 Jul 20;110(3):247-52.[Abstract]
Key Articles
Referenced Articles
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