Roszet

Adult Dosing .

Dosage forms:  TAB: 5 mg/10 mg, 10 mg/10 mg, 20 mg/10 mg, 40 mg/10 mg

primary hyperlipidemia

[1 tab PO qd]

Info: may adjust dose q4wk; start 5 mg/10 mg PO qd in Asian patients (risk of incr. drug levels); may convert from rosuvastatin monotherapy w/ same rosuvastatin dose; search 'cholesterol' for epocrates Adult Cholesterol Tx Selector decision tool

homozygous familial hypercholesterolemia

[1 tab PO qd]

Info: may adjust dose q4wk; start 5 mg/10 mg PO qd in Asian patients (risk of incr. drug levels); may convert from rosuvastatin monotherapy w/ same rosuvastatin dose; search 'cholesterol' for epocrates Adult Cholesterol Tx Selector decision tool

renal dosing

[see below]

CrCl <30: start 5 mg/10 mg qd, max 10 mg/10 mg qd

HD: avoid use, dose adjustment not possible w/ fixed-dose combo; PD: not defined

hepatic dosing

[see below]

Child-Pugh Class B or C: avoid use; acute hepatic failure or decompensated cirrhosis: contraindicated

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.