Prevnar 20

Adult Dosing .

Dosage forms:  INJ

invasive pneumococcal disease prevention

[no or unknown pneumococcal vaccine history]

Dose: 0.5 mL IM x1; Info: for patients 50 yo and older and high-risk patients <50 yo; search 'immunization' for epocrates Adult Immunization decision tool including links to CDC/ACIP schedules

[previously received PCV7 only]

Dose: 0.5 mL IM x1; Info: for patients 50 yo and older and high-risk patients <50 yo; search 'immunization' for epocrates Adult Immunization decision tool including links to CDC/ACIP schedules

[previously received PCV13 only]

Dose: 0.5 mL IM x1; Start: >1y after PCV13; Info: for patients 50 yo and older and high-risk patients <50 yo; search 'immunization' for epocrates Adult Immunization decision tool including links to CDC/ACIP schedules

[previously received PPSV23 only]

Dose: 0.5 mL IM x1; Start: >1y after PPSV23; Info: for patients 50 yo and older and high-risk patients <50 yo; search 'immunization' for epocrates Adult Immunization decision tool including links to CDC/ACIP schedules

[previously received PCV13 and PPSV23, <50 yo]

Dose: 0.5 mL IM x1; Start: >5y after last pneumococcal vaccine dose; Info: for patients with cochlear implant, CSF leak, or immunocompromised patients; search 'immunization' for epocrates Adult Immunization decision tool including links to CDC/ACIP schedules

[previously received PCV13 and PPSV23, 65 yo and older]

Dose: 0.5 mL IM x1; Start: >5y after last pneumococcal vaccine dose; Info: give based on shared clinical decision-making if PPSV23 received at 65 yo and older; search 'immunization' for epocrates Adult Immunization decision tool including links to CDC/ACIP schedules

renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

hepatic dosing

[no adjustment]

Peds Dosing .

Dosage forms:  INJ

otitis media and invasive pneumococcal disease prevention

[6 wk old-6 mo at series start]

Dose: 0.5 mL IM x2 doses at least 4wk apart, then 0.5 mL IM x1 when patient >1 yo and at least 8wk after prior dose; Info: may give 1st dose as early as 6 wk old; give 4th dose at least 8wk after 3rd dose; search 'immunization' for epocrates Child/Adolescent Immunization decision tool including links to CDC/ACIP schedules

[7-11 mo at series start]

Dose: 0.5 mL IM x2 doses at least 4wk apart, then 0.5 mL IM x1 when patient >1 yo and at least 8wk after prior dose; Info: search 'immunization' for epocrates Child/Adolescent Immunization decision tool including links to CDC/ACIP schedules

[12-23 mo at series start]

Dose: 0.5 mL IM x2 doses at least 8wk apart; Info: search 'immunization' for epocrates Child/Adolescent Immunization decision tool including links to CDC/ACIP schedules

[24-59 mo at series start, healthy patients]

Dose: 0.5 mL IM x1; Info: search 'immunization' for epocrates Child/Adolescent Immunization decision tool including links to CDC/ACIP schedules

[24-71 mo at series start, patients with high infection risk]

Dose: 0.5 mL IM x2 doses at least 8wk apart; Info: search 'immunization' for epocrates Child/Adolescent Immunization decision tool including links to CDC/ACIP schedules

[6 yo and older at series start, patients with high infection risk]

Dose: 0.5 mL IM x1 dose; Info: search 'immunization' for epocrates Child/Adolescent Immunization decision tool including links to CDC/ACIP schedules

renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

hepatic dosing

[no adjustment]