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bismuth subsalicylate and metronidazole and tetracycline
generic
Black Box Warnings .
Potential for Carcinogenicity
metronidazole shown to be carcinogenic in mice and rats; unknown if metronidazole is associated w/ carcinogenicity in humans
Adult Dosing .
Dosage forms: convenience pack
Special Note
- [convenience pack components]
- Info: 1-day pack contains bismuth subsalicylate 262.4 mg CH tab x8 and metronidazole 250 mg tab x4 and tetracycline 500 mg cap x4
H. pylori infection
- [1 dose PO qid x14 days]
- Info: 1 dose = 2 bismuth subsalicylate CH tabs + 1 metronidazole tab + 1 tetracycline cap; give w/ PPI; give w/ meals and at bedtime w/ full glass of water; search 'H. pylori Tx' for epocrates H. pylori Tx Regimens decision tool
renal dosing
- [see below]
- mild-moderate impairment: not defined, caution advised; severe impairment: contraindicated
- HD/PD: not defined
hepatic dosing
- [see below]
- mild-moderate impairment: not defined, caution advised; severe impairment: avoid use
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.