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Atacand HCT
candesartan cilexetil/ hydrochlorothiazide
Black Box Warnings .
Fetal Toxicity
fetal/neonatal morbidity/mortality may occur when drugs that act directly on the renin-angiotensin system are used in pregnancy; D/C drug ASAP once pregnancy detected
Adult Dosing .
Dosage forms: TAB: 16 mg/12.5 mg, 32 mg/12.5 mg, 32 mg/25 mg
HTN
- [1-2 tabs PO divided qd-bid]
- Max: 32 mg/25 mg/day
renal dosing
- [see below]
- CrCl >30: no adjustment; CrCl 10-30: not defined, caution advised; CrCl <10: avoid use; anuria: contraindicated
- HD/PD: avoid use
hepatic dosing
- [see below]
- moderate-severe impairment: avoid use, dose adjustment not possible w/ fixed-dose combo
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.