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Interaction Check

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Selected Drugs Clear All

  • remove Advil Dual Action with Acetaminophen Back Pain
    acetaminophen/ ibuprofen
  • remove amitriptyline
    generic
  • remove budesonide/ formoterol inhaled
    generic
  • remove Dr. Scholl's Ingrown Toenail Pain Reliever
    sodium sulfide topical
  • remove Lynparza
    olaparib
  • remove Prevymis
    letermovir
  • remove Rectiv
    nitroglycerin intra-anal

multicheck MultiCheck Results - 5 Interactions

Smiley face Smiley face

Avoid/Use Alternative

Smiley face Smiley face Lynparza (olaparib) + Prevymis (letermovir)

Avoid/Use Alternative


olaparib + letermovir

use alternative or monitor CBC; decr. olaparib dose to 150 mg bid: combo may incr. olaparib levels, risk of myelosuppression, other adverse effects (hepatic metabolism inhibited)

Monitor/Modify Tx

Smiley face Smiley face Advil Dual Action with Acetaminophen Back Pain (acetaminophen/ ibuprofen) + budesonide/formoterol inhaled (generic)

Monitor/Modify Tx


ibuprofen + formoterol inhaled

monitor BP: combo may incr. risk of HTN (additive effects)

Smiley face Smiley face Advil Dual Action with Acetaminophen Back Pain (acetaminophen/ ibuprofen) + Lynparza (olaparib)

Monitor/Modify Tx


ibuprofen + olaparib

monitor thrombosis s/sx; use lowest effective ibuprofen dose, shortest effective tx duration: combo may incr. risk of thromboembolism (additive effects)

Smiley face Smiley face amitriptyline (generic) + budesonide/formoterol inhaled (generic)

Monitor/Modify Tx


amitriptyline + formoterol inhaled

monitor BP, HR during and x2wk after amitriptyline D/C: combo may incr. risk of HTN, tachycardia, other cardiovascular adverse effects (additive effects)

Smiley face Smiley face amitriptyline (generic) + Rectiv (nitroglycerin intra-anal)

Monitor/Modify Tx


amitriptyline + nitroglycerin

monitor BP: combo may incr. risk of severe hypotension, including orthostasis, syncope (additive effects)

Additional Considerations

Smiley face Smiley face amitriptyline

add MAO inhibitor to Interaction Check if recent (14 days) use

Smiley face Smiley face nitroglycerin in Rectiv

if SL nitroglycerin tab use, caution advised with anticholinergic drugs, tricyclic antidepressants, other drugs that may cause xerostomia; combo may delay vasodilator onset, decr. nitroglycerin peak levels, efficacy; absorption decreased, xerostomia may alter dissolution of SL tab

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