Selected Drugs Clear All
MultiCheck Results
- 2
Interactions
Avoid/Use Alternative |
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amphetamine
(generic) + pentazocine/naloxone
(generic) |
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Avoid/Use Alternativeamphetamine + pentazocine use alternative or monitor serotonin syndrome sx, especially during initiation/titration; decr. amphetamine start dose: combo may incr. risk of serotonin syndrome (additive effects) |
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Monitor/Modify Tx |
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pentazocine/naloxone
(generic) + Urecholine
(bethanechol) |
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Monitor/Modify Txpentazocine + bethanechol monitor BP: combo may incr. risk of severe hypotension, including orthostasis, syncope (additive effects) |
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Additional Considerations |
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amphetamine
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add MAO inhibitor to Interaction Check if recent (14 days) use avoid combo with beverages or products containing ethanol and Adzenys XR-ODT, Dyanavel XR, Mydayis, generic extended-release orally disintegrating tablet (ER ODT) formulations; combo may incr. amphetamine release rate, levels, risk of adverse effects, decr. duration of efficacy |
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pentazocine
in pentazocine/naloxone
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consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use |
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naloxone (abuse deterrent)
in pentazocine/naloxone
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no pharmacologic activity when administered as directed |
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somatropin
in Zomacton
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caution advised with drugs metabolized by CYP450 liver enzymes; somatropin may increase CYP450 metabolic function, alter levels of concomitant drugs, incr. risk of adverse effects or decr. efficacy lonapegsomatropin is a prodrug of somatropin; similar interactions anticipated |
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