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Interaction Check

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Selected Drugs Clear All

  • remove anastrozole
    generic
  • remove Coumadin
    warfarin
  • remove Stavzor
    valproic acid

multicheck MultiCheck Results - 1 Interaction

Smiley face Smiley face

Monitor/Modify Tx

Smiley face Smiley face Coumadin (warfarin) + Stavzor (valproic acid)

Monitor/Modify Tx


warfarin + valproic acid

monitor INR, bleeding s/sx: combo may decr. warfarin levels, efficacy; may incr. risk of bleeding, including life-threatening (hepatic metabolism induced; synergistic effects)

Additional Considerations

Smiley face Smiley face warfarin in Coumadin

monitor INR more frequently when starting, adjusting, or stopping other drugs, including short-term therapies, OTC drugs, herbal supplements; drug interaction mechanisms do not always predict anticoagulation effects due to high inter- and intra-patient variability

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