Selected Drugs Clear All
MultiCheck Results
- 4
Interactions
Avoid/Use Alternative |
||
|
Desoxyn
(methamphetamine) + Zoloft
(sertraline) |
||
Avoid/Use Alternativemethamphetamine + sertraline use alternative or decr. methamphetamine start dose; monitor serotonin syndrome sx, especially during initiation/titration: combo may incr. risk of serotonin syndrome (additive effects) |
||
|
Xyrem
(sodium oxybate) + Zoloft
(sertraline) |
||
Avoid/Use Alternativeoxybate + sertraline use alternative or monitor respiratory rate; decr. dose of one or both drugs: combo may incr. risk of profound CNS and respiratory depression, psychomotor impairment, hypotension, syncope (additive effects) |
||
Monitor/Modify Tx |
||
|
Desoxyn
(methamphetamine) + Paxlovid
(nirmatrelvir and ritonavir) |
||
Monitor/Modify Txmethamphetamine + ritonavir monitor serotonin syndrome sx, especially during initiation/titration: combo may incr. methamphetamine levels, risk of serotonin syndrome, other adverse effects (hepatic metabolism possibly inhibited) |
||
|
Paxlovid
(nirmatrelvir and ritonavir) + Zoloft
(sertraline) |
||
Monitor/Modify Txritonavir + sertraline monitor ECG: combo may incr. sertraline levels, risk of QT prolongation, cardiac arrhythmias, other adverse effects (hepatic metabolism inhibited) |
||
Additional Considerations |
||
|
nirmatrelvir
in Paxlovid
|
||
|
patients on ritonavir- or cobicistat-containing HIV or HCV regimens may continue their tx as indicated |
||
|
sertraline
in Zoloft
|
||
|
add MAO inhibitor to Interaction Check if recent (14 days) use |
||
|
methamphetamine
in Desoxyn
|
||
|
add MAO inhibitor to Interaction Check if recent (14 days) use |
||