Selected Drugs Clear All
MultiCheck Results
- 7
Interactions
Avoid/Use Alternative |
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Soliqua 100/33
(insulin glargine/ lixisenatide) + Vestura
(drospirenone/ ethinyl estradiol) |
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Avoid/Use Alternativelixisenatide + drospirenone (contraceptive) consider alternative or monitor glucose; give drospirenone at least 1h before or at least 11h after lixisenatide: combo may decr. peak drospirenone levels, contraceptive efficacy; may decr. antidiabetic agent efficacy (absorption delayed, possibly decreased; antagonistic effects) lixisenatide + ethinyl estradiol (contraceptive) consider alternative or monitor glucose; give oral ethinyl estradiol at least 1h before or at least 11h after lixisenatide: combo may decr. peak ethinyl estradiol levels, contraceptive efficacy; may decr. antidiabetic agent efficacy (absorption delayed, possibly decreased; antagonistic effects) Monitor/Modify Txinsulin + drospirenone (contraceptive) monitor glucose: combo may decr. antidiabetic agent efficacy (antagonistic effects) insulin + ethinyl estradiol (contraceptive) monitor glucose: combo may decr. antidiabetic agent efficacy (antagonistic effects) |
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Monitor/Modify Tx |
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NovoLog
(insulin aspart) + Soliqua 100/33
(insulin glargine/ lixisenatide) |
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Monitor/Modify Txinsulin + lixisenatide monitor glucose; consider dose adjustment of one or both drugs: combo may incr. risk of hypoglycemia (additive effects) |
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NovoLog
(insulin aspart) + Vestura
(drospirenone/ ethinyl estradiol) |
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Monitor/Modify Txinsulin + drospirenone (contraceptive) monitor glucose: combo may decr. antidiabetic agent efficacy (antagonistic effects) insulin + ethinyl estradiol (contraceptive) monitor glucose: combo may decr. antidiabetic agent efficacy (antagonistic effects) |
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Additional Considerations |
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lixisenatide
in Soliqua 100/33
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caution advised with oral drugs, especially narrow therapeutic index; lixisenatide delays gastric emptying, may alter absorption of concomitant oral drugs |
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