Selected Drugs Clear All

  • remove Infumorph
    morphine sulfate
  • remove Lasix
    furosemide

multicheck MultiCheck Results - 1 Interaction

Smiley face Smiley face

Monitor/Modify Tx
Smiley face Smiley face Infumorph (morphine sulfate) + Lasix (furosemide)

Monitor/Modify Tx

morphine + furosemide

monitor BP: combo may incr. risk of severe hypotension, including orthostasis, syncope; may decr. furosemide efficacy (additive effects; antagonistic effects, opioids may induce antidiuretic hormone release)

Additional Considerations
Smiley face Smiley face morphine in Infumorph

consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use

add MAO inhibitor to Interaction Check if recent (14 days) use

avoid combo with beverages or products containing ethanol and some morphine extended-release (ER) capsules; combo may incr. morphine release rate, levels, risk of adverse effects, including life-threatening overdose, decr. duration of efficacy
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