Diabetes Res Clin Pract

COVID-19 booster may cause small increases in glucose in T1DM patients

September 22, 2023

Researchers say patients with type 1 diabetes should closely monitor glucose levels after vaccination, as they may have elevated glucose levels a few days after receiving a COVID-19 booster.

• In this single-center, prospective cohort study of adults with type 1 diabetes, participants wore blinded Dexcom G6 Pro continuous glucose monitors for 10 days. 
• Among the 21 enrolled participants (mean age 47.4; 62% women), 38% received a Moderna booster and 62% a Pfizer-BioNTech booster. 
• Compared to baseline (162.9 ± 44.1 mg/dL), mean glucose was significantly increased at Day 2 (172.8 ± 47.0 mg/dL; p = 0.04) and Day 3 (173.1 ± 45.0 mg/dL; p = 0.02) post-vaccination. 
•  Insulin resistance was also increased on Day 2 (p = 0.03). 
• There were no differences in outcome metrics between booster vaccine manufacturers.

Source:

Zilbermint M, et al. (2023, September 9). Diabetes Res Clin Pract. Effects of the COVID-19 booster vaccine on glycemia and insulin resistance in people with type 1 diabetes: A prospective pilot study. https://pubmed.ncbi.nlm.nih.gov/37678726/