Select a medication above to begin.
Retin-A Micro
tretinoin topical
Peds Dosing .
- Dosage forms: GEL: 0.04%, 0.06%, 0.08%, 0.1%
acne vulgaris
- [12 yo and older]
- Dose: apply qhs
Contraindications / Cautions .
- hypersensitivity to drug or ingredient
- avoid: sun exposure
- avoid: UV light exposure, artificial
- caution: hypersensitivity to fish (0.05% gel or 0.05% lotion form)
- caution: sunburn
- caution: eczema
Drug Interactions .
Overview
tretinoin topical
retinoid topical
- photosensitivity
- skin irritant/drying agent
Avoid/Use Alternative
- aminolevulinic acid topical
- porfimer
- tazarotene topical
Caution Advised
- acitretin
- adapalene topical
- benzoyl peroxide topical
- isotretinoin
- methoxsalen
- salicylic acid topical
- sulfur topical
- trifarotene topical
- verteporfin
Adverse Reactions .
Serious Reactions
- skin rxn, severe
Common Reactions
- peeling
- xeroderma
- burning
- stinging
- erythema
- pruritus
- blistering
- photosensitivity
Safety/Monitoring .
Monitoring Parameters
no routine tests recommended
Look/Sound-Alike Drug Names
tretinoin confused with: ISOtretinoin; Tenormin; triamcinolone acetonide
Pregnancy/Lactation .
Pregnancy
Clinical Summary
weigh risk/benefit during pregnancy; risk of teratogenicity and holoprosencephaly low based on limited human data and minimal systemic absorption; risk of teratogenicity and fetal death based on human data w/ systemic retinoids
Lactation
Clinical Summary
may use while breastfeeding; no human data available, though low risk of infant harm based on minimal maternal systemic absorption; no human data available to assess effects on milk production
Pharmacology .
Metabolism: skin; CYP450: 2S1, 26 substrate; Info: minimal systemic absorption
Excretion: urine, feces; Half-life: unknown
Subclass: Acne, Topical Agents
Mechanism of Action
exact mechanism of action unknown; binds to retinoic acid receptors, stimulating epithelial cell turnover (retinoid)
Formulary .
No Formulary Selected
Join Now to View Patient Handouts!
Create a FREE epocrates Online account to access patient medication instructions. Your patients and caregivers will appreciate you printing these friendly handouts, available in English and Spanish. Each handout addresses common concerns such as how to take the medication, and possible side effects.
Current Members: Sign In.
Pill Pictures
Join Now to View Pill Pictures!
Create a FREE epocrates Online account to access full-color images of medications within the drug monograph.
Current Members: Sign In.