The clinical information you need, at your fingertips.

The anesthesia produces a profile that overlaps with both sleep and coma but also carries distinct signatures, which could potentially be tuned closer to sleep to reduce cognitive side effects. . .

Combining imaging and a biomarker of heart strain with clinical history caught a broader range of adverse outcomes than current tools, which predict sudden cardiac death alone. . .

First-trimester use of nonsteroidal anti-inflammatory drugs was not associated with major congenital malformations in a large pregnancy registry. . .

Cancer incidence rose sharply with weight gained between late adolescence and midlife, with effects often larger than those tied to BMI at a single point. . .

New analyses suggest semaglutide produces substantial weight loss in women before, during, and after menopause, with possible cardiovascular and migraine benefits. . .

In adults not actively seeking smoking treatment, brief varenicline sampling increased smoking abstinence and outperformed nicotine replacement therapy on some measures. . .

Exercise improved smoking abstinence and reduced cigarette use in a large meta-analysis, while even brief activity sessions sharply lowered cravings during high-risk relapse periods. . .

In a large real-world cohort study, women with breast cancer and obesity or type 2 diabetes who used GLP-1 receptor agonists had substantially lower ten-year all-cause mortality and cancer recurrence than matched patients on other treatments. . .

A pragmatic trial of genotype-guided SSRI prescribing found no benefit at three months but higher remission rates at six months, suggesting the value of pharmacogenetic testing emerges over time rather than immediately. . .