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Dulcolax Laxative
bisacodyl
Dosing .
6-11 yo
- [ oral DR tablet ]
- Dose: 1 tab PO qd prn; Info: do not cut/crush/chew tab
12 yo and older
- [ oral DR tablet ]
- Dose: 1-3 tabs PO qd prn; Info: do not cut/crush/chew tab
renal dosing
- [ peds ]
- renal impairment: not defined, consider adult renal dosing for guidance
- HD/PD: not defined
- [ adults ]
- renal impairment: no adjustment
- HD/PD: not defined
hepatic dosing
- [ not defined ]
Contraindications / Cautions .
- hypersensitivity to drug or ingredient
- acute abdomen
- abdominal pain, undiagnosed
- nausea, undiagnosed
- vomiting, undiagnosed
- GI obstruction
- ileus
- GI perforation
- toxic megacolon
- gastroenteritis
- rectal bleeding
- appendicitis
- caution: inflammatory bowel dz
Drug Interactions .
Overview
bisacodyl
stimulant laxative
- colonic mucosal ulceration
- gastric pH sensitive
Avoid/Use Alternative
- polyethylene glycol
- polyethylene glycol/electrolytes
- sodium picosulfate
- sulfate bowel prep
Monitor/Modify Tx
- aluminum hydroxide
- calcium carbonate
- magnesium carbonate
- magnesium hydroxide
- magnesium oxide
- sodium bicarbonate
- sodium citrate
- sodium zirconium cyclosilicate
- trofinetide
Caution Advised
- cimetidine
- dexlansoprazole
- esomeprazole
- famotidine
- lansoprazole
- magnesium citrate
- nizatidine
- omeprazole
- pantoprazole
- rabeprazole
- sodium phosphate rectal
- vonoprazan
Adverse Reactions .
Serious Reactions
- electrolyte imbalance (long-term use)
- cathartic colon (long-term use)
- ischemic colitis (high-dose use)
Common Reactions
- nausea
- abdominal cramps
- vomiting
- rectal sensation burning
- diarrhea
Pregnancy/Lactation .
Pregnancy
Clinical Summary
may use during pregnancy; no human data available, though risk of fetal harm not expected based on minimal systemic absorption
Lactation
Clinical Summary
may use while breastfeeding; no human data available, though risk of infant harm and adverse effects on milk production not expected based on minimal systemic absorption in breastfeeding patients
Pharmacology .
Metabolism: liver; CYP450: unknown; Info: 15% systemic absorption
Excretion: feces primarily, urine; Half-life: unknown
Subclass: Constipation: Stimulant Laxatives
Mechanism of Action: increases peristalsis
Alternatives .
Search for Alternative Products by:
- Other OTCs w/ Same Active Ingredient(s)
- Dulcolax Pink Laxative: oral DR tablet
- Fleet Stimulant Oral Laxative: oral DR tablet
- Same Subclass
- Constipation: Stimulant Laxatives
- Related Subclasses
- Bowel Preps
- Constipation: Bulk Laxatives
- Constipation: Guanylate Cyclase-C (GC-C) Agonists
- Constipation: Lubricant Laxatives
- Constipation: Osmotic Laxatives
- Constipation: Prostaglandins
- Constipation: Serotonin (5-HT4) Receptor Agonists
- Constipation: Stool Softeners
- Irritable Bowel Syndrome (IBS)
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