Highlights & Basics
- Sialadenitis is the inflammation and enlargement of one or several major salivary glands. It most commonly affects parotid and submandibular glands.
- Bacterial infection can occur if salivary flow is diminished by illness or medication, or is obstructed by a sialolith (salivary stone). Most commonly caused by Staphylococcus aureus.
- Intermittent painless unilateral or bilateral swellings without accompanying signs of infection may be idiopathic or due to an underlying condition, such as ductal stenosis or autoimmune disease.
- Chronic sclerosing sialadenitis presents as a painless unilateral swelling that can mimic tumors. Biopsy is required for diagnosis.
- Airway compromise is an important potential consequence of acute glandular swelling.
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Definition
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Citations
Fattahi TT, Lyu PE, Van Sickels JE. Management of acute suppurative parotitis. J Oral Maxillofac Surg. 2002;60:446-448.[Abstract]
Kraaij S, Karagozoglu KH, Forouzanfar T, et al. Salivary stones: symptoms, aetiology, biochemical composition and treatment. Br Dent J. 2014 Dec 5;217(11):E23.[Abstract][Full Text]
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18. Fattahi TT, Lyu PE, Van Sickels JE. Management of acute suppurative parotitis. J Oral Maxillofac Surg. 2002;60:446-448.[Abstract]
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28. Kraaij S, Karagozoglu KH, Forouzanfar T, et al. Salivary stones: symptoms, aetiology, biochemical composition and treatment. Br Dent J. 2014 Dec 5;217(11):E23.[Abstract][Full Text]
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42. European Medicines Agency. Quinolone and fluoroquinolone-containing medicinal products. November 2018 [internet publication].[Full Text]
43. Medicines and Healthcare products Regulatory Agency. Fluoroquinolone antibiotics: new restrictions and precautions for use due to very rare reports of disabling and potentially long-lasting or irreversible side effects. March 2019 [internet publication].[Full Text]
44. Food and Drug Administration. FDA Drug Safety Communication: FDA advises restricting fluoroquinolone antibiotic use for certain uncomplicated infections; warns about disabling side effects that can occur together. December 2016 [internet publication].[Full Text]
45. Food and Drug Administration. FDA warns about increased risk of ruptures or tears in the aorta blood vessel with fluoroquinolone antibiotics in certain patients. December 2018 [internet publication].[Full Text]
46. Food and Drug Administration. FDA reinforces safety information about serious low blood sugar levels and mental health side effects with fluoroquinolone antibiotics; requires label changes. October 2018 [internet publication].[Full Text]
47. Marchal F, Bradley PJ. Treatment of infections and inflammatory conditions. In: Management of infections of the salivary glands. Berlin, Germany: Springer Berlin Heidelberg. 2007:169-176.
48. National Institute for Health and Care Excellence. Therapeutic sialendoscopy - Interventional procedures guidance [IPG218]. May 2007 [internet publication].[Full Text]
49. Strychowsky JE, Sommer DD, Gupta MK, et al. Sialendoscopy for the management of obstructive salivary gland disease: A systematic review and meta-analysis. Arch Otolaryngol Head Neck Surg. 2012;138:541-547.[Abstract]
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