Zykadia

Adult Dosing .

Dosage forms:  CAP: 150 mg; TAB: 150 mg

Special Note

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments

non-small cell lung CA, metastatic

[ALK-positive dz]

Dose: 450 mg PO qd; Info: give w/ food

[ROS1-positive dz (off-label)]

Dose: 450 mg PO qd; Info: give w/ food

renal dosing

[see below]

CrCl >30: no adjustment; CrCl <30: not defined

HD/PD: not defined

hepatic dosing

[adjust dose amount]

Child-Pugh Class C: decr. usual dose by 33%

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.