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Diseases

Paradoxical vocal fold motion

OVERVIEW

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  • Images

DIAGNOSIS

  • Diagnostic Approach
  • Risk Factors
  • History & Exam
  • Tests
  • Differential Diagnosis
  • Criteria
  • Screening

TREATMENT

  • Tx Approach
  • Tx Options
  • Emerging Tx
  • Prevention

FOLLOW-UP

  • Overview
  • Complications

REFERENCES

  • Citations
  • Guidelines
  • Credits

PATIENT RESOURCES

  • Patient Instructions

Highlights & Basics

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Key Highlights
  • Paradoxical vocal fold motion (intermittent laryngeal obstruction) (PVFM/ILO) is a breathing disorder that is frequently mistaken for asthma.

  • Accurate diagnosis is made by a multidisciplinary team, which can include a speech language pathologist, a primary care physician, an asthma/allergy specialist, a pulmonologist, a psychologist, a psychiatrist, a sports medicine specialist, an athletic trainer, and a gastroenterologist.

  • Diagnosis is established through the case history, continuous laryngeal visualization during exercise, and pulmonary function studies.

  • Behavioral therapy by a speech language pathologist is the standard treatment.

Laryngopharyngeal reflux: bilateral edema and erythema of the vocal folds with epithelial layer thic
Laryngopharyngeal reflux: bilateral edema and erythema of the vocal folds with epithelial layer thickness, interarytenoid thickness
From the collection of the University of Wisconsin School of Medicine and Public Health

Quick Reference

  • History & Exam

    • Key Factors

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      • Diagnostics Tests

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        • Treatment Options

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          Definition

          Epidemiology

          Etiology

          Pathophysiology

          content by BMJ Group
          Last updated

          Images

          • Normal larynx: normal color of vocal folds and surrounding structures, smooth vocal fold edges

            Normal larynx: normal color of vocal folds and surrounding structures, smooth vocal fold edges

          • Irritable larynx: bilateral erythema of the arytenoid complex bilaterally with tissue changes sugges

            Irritable larynx: bilateral erythema of the arytenoid complex bilaterally with tissue changes suggestive of early granuloma

          • Laryngopharyngeal reflux: bilateral edema and erythema of the vocal folds with epithelial layer thic

            Laryngopharyngeal reflux: bilateral edema and erythema of the vocal folds with epithelial layer thickness, interarytenoid thickness

          • Reproduction of breathing attack: adduction of arytenoid complex during inhalation

            Reproduction of breathing attack: adduction of arytenoid complex during inhalation

          • Abduction breathing exercise: abduction of the arytenoid complex bilaterally with nasal inhalation

            Abduction breathing exercise: abduction of the arytenoid complex bilaterally with nasal inhalation

          Citations

            Key Articles

            • Morris MJ, Allan PF, Perkins PJ. Vocal cord dysfunction: etiologies and treatment. Clin Pulm Med. 2006;13:73-86.

            • Clemm HH, Olin JT, McIntosh C, et al. Exercise-induced laryngeal obstruction (EILO) in athletes: a narrative review by a subgroup of the IOC Consensus on 'acute respiratory illness in the athlete'. Br J Sports Med. 2022 Jun;56(11):622-9.[Abstract][Full Text]

            • Leong P, Vertigan AE, Hew M, et al. Diagnosis of vocal cord dysfunction/inducible laryngeal obstruction: an international delphi consensus study. J Allergy Clin Immunol. 2023 Oct;152(4):899-906.[Abstract][Full Text]

            Referenced Articles

            • 1. Andrianopoulos MV, Gallivan GJ, Gallivan KH. PVCM, PVCD, EPL, and irritable larynx syndrome: what are we talking about and how do we treat it? J Voice. 2000;14:607-618.[Abstract]

            • 2. Maschka DA, Bauman NM, McCray PB Jr, et al. A classification scheme for paradoxical vocal cord motion. Laryngoscope. 1997;107:1429-1435.[Abstract]

            • 3. Mathers-Schmidt BA. Paradoxical vocal fold motion: a tutorial on a complex disorder and the speech-language pathologist's role. Am J Speech Lang Pathol. 2001;10:111-25.

            • 4. Al-Alwan A, Kaminsky D. Vocal cord dysfunction in athletes: clinical presentation and review of the literature. Phys Sportsmed. 2012;40:22-27.[Abstract]

            • 5. Patel RR, Venediktov R, Schooling T, et al. Evidence-based systematic review: effects of speech-language pathology treatment for individuals with paradoxical vocal fold motion. Am J Speech Lang Pathol. 2015;24:566-584.[Abstract]

            • 6. Christensen PM, Heimdal JH, Christopher KL, et al. ERS/ELS/ACCP 2013 international consensus conference nomenclature on inducible laryngeal obstructions. Eur Respir Rev. 2015 Sep;24(137):445-50.[Abstract][Full Text]

            • 7. Sachdeva R, Hussain E, Moss MM, et al. Vocal cord dysfunction and feeding difficulties after pediatric cardiovascular surgery. J Pediatr. 2007;151:312-5.[Abstract]

            • 8. Silvers WS, Levine JS, Poole JA, et al. Inlet patch of gastric mucosa in upper esophagus causing chronic cough and vocal cord dysfunction. Ann Allergy Asthma Immunol. 2006;96:112-5.[Abstract]

            • 9. Neema PK, Sinha PK, Varma PK, et al. Vocal cord dysfunction in two patients after mitral valve replacement: consequences and mechanism. J Cardiothorac Vasc Anesth. 2005;19:83-5.[Abstract]

            • 10. Kinghorn K, Dhamee S. Paradoxical vocal cord motion: a postoperative dilemma - a case report. Middle East J Anesthesiol. 2006;18:1203-7.[Abstract]

            • 11. Arndt GA, Voth BR. Paradoxical vocal cord motion in the recovery room: a masquerader of pulmonary dysfunction. Can J Anaesth. 1996;43:1249-51.[Abstract]

            • 12. Hammer G, Schwinn D, Wollman H. Postoperative complications due to paradoxical vocal cord motion. Anesthesiology. 1987;66:686-7.[Abstract]

            • 13. Harbison J, Dodd J, McNicholas WT. Paradoxical vocal cord motion causing stridor after thyroidectomy. Thorax. 2000;55:533-4.[Abstract][Full Text]

            • 14. Michelsen LG, Vanderspek AF. An unexpected functional cause of upper airway obstruction. Anaesthesia. 1988;43:1028-30.[Abstract]

            • 15. Roberts KW, Crnkovic A, Steiniger JR. Post-anesthesia paradoxical vocal cord motion successfully treated with midazolam. Anesthesiology. 1998;89:517-9.[Abstract]

            • 16. Sukhani R, Barclay J, Chow J. Paradoxical vocal cord motion: an unusual cause of stridor in the recovery room. Anesthesiology. 1993;79:177-80.[Abstract]

            • 17. Bastian RW, Richardson BE. Postintubation phonatory insufficiency: an elusive diagnosis. Otolaryngol Head Neck Surg. 2001;124:625-33.[Abstract]

            • 18. Powell SA, Nguyen CT, Gaziano J, et al. Mass psychogenic illness presenting as acute stridor in an adolescent female cohort. Ann Otol Rhinol Laryngol. 2007;116:525-531.[Abstract]

            • 19. Kenn K, Willer G, Bizer C, et al. Prevalence of vocal cord dysfunction in patients with dyspnea: first prospective clinical study. Am J Respir Crit Care Med. 1997;155:A965.

            • 20. Morris MJ, Allan PF, Perkins PJ. Vocal cord dysfunction: etiologies and treatment. Clin Pulm Med. 2006;13:73-86.

            • 21. Brugman S. The many faces of vocal cord dysfunction: what 36 years of literature tells us. Am J Respir Crit Care Med. 2003;167:A588.

            • 22. Johansson H, Norlander K, Berglund L, et al. Prevalence of exercise-induced bronchoconstriction and exercise-induced laryngeal obstruction in a general adolescent population. Thorax. 2015 Jan;70(1):57-63.[Abstract][Full Text]

            • 23. Ersson K, Mallmin E, Malinovschi A, et al. Prevalence of exercise-induced bronchoconstriction and laryngeal obstruction in adolescent athletes. Pediatr Pulmonol. 2020 Dec;55(12):3509-16.[Abstract][Full Text]

            • 24. Nielsen EW, Hull JH, Backer V. High prevalence of exercise-induced laryngeal obstruction in athletes. Med Sci Sports Exerc. 2013 Nov;45(11):2030-5.[Abstract][Full Text]

            • 25. Morris MJ, Deal LE, Bean DR, et al. Vocal cord dysfunction in patients with exertional dyspnea. Chest. 1999;116:1676-82.[Abstract][Full Text]

            • 26. Campisi ES, Schneiderman JE, Owen B, et al. Exercise-induced laryngeal obstruction: Quality initiative to improve assessment and management. Int J Pediatr Otorhinolaryngol. 2019 Dec;127:109677.[Abstract][Full Text]

            • 27. Newman KB, Dubester SN. Vocal cord dysfunction: masquerader of asthma. Semin Respir Crit Care Med. 1994;15:161.

            • 28. Gavin LA, Wamboldt M, Brugman S, et al. Psychological and family characteristics of adolescents with vocal cord dysfunction. J Asthma. 1998;35:409-417.[Abstract]

            • 29. Dunn NM, Katial RK, Hoyte FCL. Vocal cord dysfunction: a review. Asthma Res Pract. 2015;1:9.[Abstract][Full Text]

            • 30. Low K, Lau KK, Holmes P, et al. Abnormal vocal cord function in difficult-to-treat asthma. Am J Respir Crit Care Med. 2011 Jul 1;184(1):50-6.[Abstract][Full Text]

            • 31. Hicks M, Brugman SM, Katial R. Vocal cord dysfunction/paradoxical vocal fold motion. Prim Care. 2008;35:81-103.[Abstract]

            • 32. Kenn K. Vocal cord dysfunction: what do we really know? A review [in German]. Pneumologie. 2007;61:431-439.[Abstract]

            • 33. Parker JM, Guerrero ML. Airway function in women: bronchial hyperresponsiveness, cough, and vocal cord dysfunction. Clin Chest Med. 2004;25:321-330.[Abstract]

            • 34. Fujiki RB, Olson-Greb B, Thibeault SL. Clinical profiles of children and adolescents with induced laryngeal obstruction (ILO) and exercise induced laryngeal obstruction (EILO). Ann Otol Rhinol Laryngol. 2024 Feb;133(2):136-44.[Abstract]

            • 35. Morrison M, Rammage L, Emami AJ. The irritable larynx syndrome. J Voice. 1999;13:447-55.[Abstract]

            • 36. Olivier CE, Argentão DG, Lima RP, et al. The nasal provocation test combined with spirometry establishes paradoxical vocal fold motion in allergic subjects. Allergy Asthma Proc. 2013;34:453-458.[Abstract]

            • 37. Halvorsen T, Walsted ES, Bucca C, et al. Inducible laryngeal obstruction: an official joint European Respiratory Society and European Laryngological Society statement. Eur Respir J. 2017 Sep;50(3):.[Abstract][Full Text]

            • 38. Cukier-Blaj S, Bewley A, Aviv JE, et al. Paradoxical vocal fold motion: a sensory-motor laryngeal disorder. Laryngoscope. 2008;118:367-370.[Abstract]

            • 39. Perkner JJ, Fennelly KP, Balkissoon R, et al. Irritant-associated vocal cord dysfunction. J Occup Environ Med. 1998;40:136-143.[Abstract]

            • 40. de la Hoz RE, Shohet MR, Bienenfeld LA, et al. Vocal cord dysfunction in former World Trade Center (WTC) rescue and recovery workers and volunteers. Am J Ind Med. 2008;51:161-165.[Abstract]

            • 41. Allan PF, Abouchahine S, Harvis L, et al. Progressive vocal cord dysfunction subsequent to a chlorine gas exposure. J Voice. 2006;20:291-296.[Abstract]

            • 42. Huggins JT, Kaplan A, Martin-Harris B, et al. Eucalyptus as a specific irritant causing vocal cord dysfunction. Ann Allergy Asthma Immunol. 2004;93:299-303.[Abstract]

            • 43. Munoz X, Roger A, De la Rosa D, et al. Occupational vocal cord dysfunction due to exposure to wood dust and xerographic toner. Scand J Work Environ Health. 2007;33:153-158.[Abstract]

            • 44. Smith B, Milstein C, Rolfes B, et al. Paradoxical vocal fold motion (PVFM) in pediatric otolaryngology. Am J Otolaryngol. 2017 Mar - Apr;38(2):230-232.[Abstract]

            • 45. Duflo S, Thibeault SL. Anatomy of the larynx and physiology of phonation. In: Merati AL, Bielamowicz S, eds. Textbook of laryngology. San Diego, CA: Plural Publishing; 2007:31.

            • 46. Sasaki CT, Weaver EM. Physiology of the larynx. Am J Med. 1997;103:9S-18S.[Abstract]

            • 47. Henriquez VM, Schulz GM, Bielamowicz S, et al. Laryngeal reflex responses are not modulated during human voice and respiratory tasks. J Physiol. 2007;585:779-789.[Abstract][Full Text]

            • 48. Ludlow C. Physiology of airway regulation. In: Merati AL, Bielamowicz S, eds. Textbook of laryngology. San Diego, CA: Plural Publishing; 2007:51.

            • 49. Reix P, St-Hilaire M, Praud JP. Laryngeal sensitivity in the neonatal period: from bench to bedside. Pediatr Pulmonol. 2007;42:674-682.[Abstract]

            • 50. Phua SY, McGarvey LP, Ngu MC, et al. Patients with gastro-oesophageal reflux disease and cough have impaired laryngopharyngeal mechanosensitivity. Thorax. 2005;60:488-491.[Abstract][Full Text]

            • 51. Olin JT, Clary MS, Deardorff EH, et al. Inducible laryngeal obstruction during exercise: moving beyond vocal cords with new insights. Phys Sportsmed. 2015 Feb;43(1):13-21.[Abstract]

            • 52. Hull JH, Godbout K, Boulet LP. Exercise-associated dyspnea and stridor: thinking beyond asthma. J Allergy Clin Immunol Pract. 2020 Jul-Aug;8(7):2202-8.[Abstract]

            • 53. Walsted ES, Faisal A, Jolley CJ, et al. Increased respiratory neural drive and work of breathing in exercise-induced laryngeal obstruction. J Appl Physiol (1985). 2018 Feb 1;124(2):356-63.[Abstract][Full Text]

            • 54. Clemm HH, Olin JT, McIntosh C, et al. Exercise-induced laryngeal obstruction (EILO) in athletes: a narrative review by a subgroup of the IOC Consensus on 'acute respiratory illness in the athlete'. Br J Sports Med. 2022 Jun;56(11):622-9.[Abstract][Full Text]

            • 55. Leong P, Gibson PG, Vertigan AE, et al. Vocal cord dysfunction/inducible laryngeal obstruction-2022 Melbourne Roundtable Report. Respirology. 2023 Jul;28(7):615-26.[Abstract][Full Text]

            • 56. Belafsky PC, Postma GN, Koufman JA. Validity and reliability of the reflux symptom index (RSI). J Voice. 2002;16:274-277.[Abstract]

            • 57. Kahrilas PJ, Altman KW, Chang AB, et al. Chronic Cough Due to Gastroesophageal Reflux in Adults: CHEST Guideline and Expert Panel Report. Chest. 2016 Dec;150(6):1341-1360.[Abstract][Full Text]

            • 58. Altman KW, Simpson CB, Amin MR, et al. Cough and paradoxical vocal fold motion. Otolaryngol Head Neck Surg. 2002;127:501-511.[Abstract]

            • 59. McFadden ER Jr, Zawadski DK. Vocal cord dysfunction masquerading as exercise-induced asthma. a physiologic cause for "choking" during athletic activities. Am J Respir Crit Care Med. 1996;153:942-947.[Abstract]

            • 60. Powell DM, Karanfilov BI, Beechler KB, et al. Paradoxical vocal cord dysfunction in juveniles. Arch Otolaryngol Head Neck Surg. 2000;126:29-34.[Abstract][Full Text]

            • 61. Husein OF, Husein TN, Gardner R, et al. Formal psychological testing in patients with paradoxical vocal fold dysfunction. Laryngoscope. 2008;118:740-747.[Abstract]

            • 62. Dromey C, Nissen SL, Roy N, et al. Articulatory changes following treatment of muscle tension dysphonia: preliminary acoustic evidence. J Speech Lang Hear Res. 2008;51:196-208.[Abstract]

            • 63. Grillone GA, Blitzer A, Brin MF, et al. Treatment of adductor laryngeal breathing dystonia with botulinum toxin type A. Laryngoscope. 1994;104:30-32.[Abstract]

            • 64. Larsen B, Caruso LJ, Villariet DB. Paradoxical vocal cord motion: an often misdiagnosed cause of postoperative stridor. J Clin Anesth. 2004;16:230-234.[Abstract]

            • 65. Franca MC. Differential diagnosis in paradoxical vocal fold movement (PVFM): an interdisciplinary task. Int J Pediatr Otorhinolaryngol. 2014;78:2169-2173.[Abstract]

            • 66. Gimenez LM, Zafra H. Vocal cord dysfunction: an update. Ann Allergy Asthma Immunol. 2011;106:267-274.[Abstract]

            • 67. Sandage MJ, Zelazny SK. Paradoxical vocal fold motion in children and adolescents. Lang Speech Hear Serv Sch. 2004;35:353-362.[Abstract]

            • 68. Hartley NA, Petty BE, Johnson B, et al. Comparative analysis of clinical profile: chronic cough vs paradoxical vocal fold motion. Respir Med. 2015;109:1516-1520.[Abstract]

            • 69. Vertigan AE, Gibson PG, Theodoros DG, et al. A review of voice and upper airway function in chronic cough and paradoxical vocal cord movement. Curr Opin Allergy Clin Immunol. 2007;7:37-42.[Abstract]

            • 70. Roy N, Ford CN, Bless DM. Muscle tension dysphonia and spasmodic dysphonia: the role of manual laryngeal tension reduction in diagnosis and management. Ann Otol Rhinol Laryngol. 1996;105:851-856.[Abstract]

            • 71. Mikita J, Parker J. High levels of medical utilization by ambulatory patients with vocal cord dysfunction as compared to age- and gender-matched asthmatics. Chest. 2006;129:905-908.[Abstract][Full Text]

            • 72. Gartner-Schmidt JL, Shembel AC, Zullo TG, et al. Development and validation of the Dyspnea Index (DI): a severity index for upper airway-related dyspnea. J Voice. 2014;28:775-782.[Abstract]

            • 73. De Guzman V, Ballif CL, Maurer R, et al. Validation of the dyspnea index in adolescents with exercise-induced paradoxical vocal fold motion. JAMA Otolaryngol Head Neck Surg. 2014;140:823-828.[Abstract]

            • 74. Ibrahim WH, Gheriani HA, Almohamed AA, et al. Paradoxical vocal cord motion disorder: past, present and future. Postgrad Med J. 2007;83:164-172.[Abstract]

            • 75. Leong P, Vertigan AE, Hew M, et al. Diagnosis of vocal cord dysfunction/inducible laryngeal obstruction: an international delphi consensus study. J Allergy Clin Immunol. 2023 Oct;152(4):899-906.[Abstract][Full Text]

            • 76. Wilson JJ, Wilson EM. Practical management: vocal cord dysfunction in athletes. Clin J Sport Med. 2006;16:357-360.[Abstract]

            • 77. Olin JT, Clary MS, Connors D, et al. Glottic configuration in patients with exercise-induced stridor: a new paradigm. Laryngoscope. 2014;124:2568-2573.[Abstract]

            • 78. Murry T, Cukier-Blaj S, Kelleher A, et al. Laryngeal and respiratory patterns in patients with paradoxical vocal fold motion. Respir Med. 2011;105:1891-1895.[Abstract][Full Text]

            • 79. Peters EJ, Hatley TK, Crater SE, et al. Sinus computed tomography scan and markers of inflammation in vocal cord dysfunction and asthma. Ann Allergy Asthma Immunol. 2003;90:316-322.[Abstract][Full Text]

            • 80. Aviv JE. Clinical assessment of pharyngolaryngeal sensitivity. Am J Med. 2000;108(suppl 4a):68S-72S.[Abstract]

            • 81. Nolan PK, Chrysler M, Phillips G, et al. Pulse oximetry coupled with spirometry in the emergency department helps differentiate an asthma exacerbation from possible vocal cord dysfunction. Pediatr Pulmonol. 2007;42:605-609.[Abstract]

            • 82. Richter GT, Rutter MJ, deAlarcon A, et al. Late-onset laryngomalacia: a variant of disease. Arch Otolaryngol Head Neck Surg. 2008;134:75-80.[Abstract][Full Text]

            • 83. National Institute on Deafness and Other Communication Disorders. Vocal fold paralysis. October 2011. http://www.nidcd.nih.gov/ (last accessed 28 October 2016).[Full Text]

            • 84. The Voice Foundation. Overview of diagnosis, treatment and prevention. http://www.voicefoundation.org/ (last accessed 28 October 2016).[Full Text]

            • 85. Landwehr LP, Wood RP 2nd, Blager FB, et al. Vocal cord dysfunction mimicking exercise-induced bronchospasm in adolescents. Pediatrics. 1996;98:971-974.[Abstract]

            • 86. Jain S, Bandi V, Officer T, et al. Role of vocal cord function and dysfunction in patients presenting with symptoms of acute asthma exacerbation. J Asthma. 2006;43:207-12.[Abstract]

            • 87. Wolfe JM, Meth BM. Vocal cord dysfunction mimicking a severe asthma attack. J Emerg Med. 1999;17:39-41.[Abstract]

            • 88. Baldwin MK, Benumof JL. Paradoxical vocal cord movement: a unique case of occurrence and treatment. Anesthesiology. 2007;107:359.[Abstract]

            • 89. Weir M. Vocal cord dysfunction mimics asthma and may respond to heliox. Clin Pediatr (Phila). 2002;41:37-41.[Abstract]

            • 90. Gose JE. Acute workup of vocal cord dysfunction. Ann Allergy Asthma Immunol. 2003;91:318.[Abstract]

            • 91. Murry T, Sapienza C. The role of voice therapy in the management of paradoxical vocal fold motion, chronic cough, and laryngospasm. Otolaryngol Clin North Am. 2010;43:73-83, viii-ix.[Abstract]

            • 92. Reitz JR, Gorman S, Kegyes J. Behavioral management of paradoxical vocal fold motion. Perspect Voice Voice Disord; 2014;24:64-70.[Full Text]

            • 93. Johnston KL, Bradford H, Hodges H, et al. The Olin EILOBI breathing techniques: description and initial case series of novel respiratory retraining strategies for athletes with exercise-induced laryngeal obstruction. J Voice. 2018 Nov;32(6):698-704.[Abstract]

            • 94. Matrka L. Paradoxic vocal fold movement disorder. Otolaryngol Clin North Am. 2014;47:135-146.[Abstract]

            • 95. Sullivan MD, Heywood BM, Beukelman DR. A treatment for vocal cord dysfunction in female athletes: an outcome study. Laryngoscope. 2001;111:1751-1755.[Abstract]

            • 96. Gillespie A, Gartner-Schmidt J. Odor induced laryngeal hypersensitivity. Perspect Voice Voice Disord. 2006;16:10-15.

            • 97. Muralitharan P, Carlsen P, Hilland M, et al. Use of inhaled ipratropium bromide to improve exercise-induced laryngeal obstruction cannot be recommended. ERJ Open Res. 2023 Jan;9(1):00308-2022.[Abstract][Full Text]

            • 98. Koufman JA, Block C. Differential diagnosis of paradoxical vocal fold movement. Am J Speech Lang Pathol. 2008;17:327-334.[Abstract]

            • 99. Guglani L, Atkinson S, Hosanagar A, et al. A systematic review of psychological interventions for adult and pediatric patients with vocal cord dysfunction. Front Pediatr. 2014;2:82.[Abstract][Full Text]

            • 100. Ruddy BH, Davenport P, Baylor J, et al. Inspiratory muscle strength training with behavioral therapy in a case of a rower with presumed exercise-induced paradoxical vocal-fold dysfunction. Int J Pediatr Otorhinolaryngol. 2004;68:1327-1332.[Abstract]

            • 101. Mathers-Schmidt BA, Brilla LR. Inspiratory muscle training in exercise-induced paradoxical vocal fold motion. J Voice. 2005;19:635-44.[Abstract]

            • 102. Hatzelis V, Murry T. Paradoxical vocal fold motion: respiratory retraining to manage long-term symptoms. J Soc Bras Fonoaudiol. 2012;24:80-85.[Abstract]

            • 103. Sandnes A, Andersen T, Clemm HH, et al. Exercise-induced laryngeal obstruction in athletes treated with inspiratory muscle training. BMJ Open Sport Exerc Med. 2019;5(1):e000436.[Abstract][Full Text]

            • 104. Anbar RD, Hehir DA. Hypnosis as a diagnostic modality for vocal cord dysfunction. Pediatrics. 2000;106:E81.[Abstract][Full Text]

            • 105. Warnes E, Allen KD. Biofeedback treatment of paradoxical vocal fold motion and respiratory distress in an adolescent girl. J Appl Behav Anal. 2005;38:529-532.[Abstract][Full Text]

            • 106. Gallena SK, Johnson AT, Vossoughi J. Short-Term Intensive Therapy and Outcomes for Athletes With Paradoxical Vocal Fold Motion Disorder. Am J Speech Lang Pathol. 2019 Feb 21;28(1):83-95.[Abstract][Full Text]

            • 107. Katz DH, Sella O, Golan H, et al. Buteyko Breathing Technique for Exertion-Induced Paradoxical Vocal Fold Motion (EI-PVFM). J Voice. 2019 Aug 12;:.[Abstract][Full Text]

            • 108. Maillard I, Schweizer V, Broccard A, et al. Use of botulinum toxin type A to avoid tracheal intubation or tracheostomy in severe paradoxical vocal cord movement. Chest. 2000;118:874-877.[Abstract][Full Text]

            • 109. Mahoney J, Hew M, Vertigan A, et al. Treatment effectiveness for vocal cord dysfunction in adults and adolescents: a systematic review. Clin Exp Allergy. 2022 Mar;52(3):387-404.[Abstract]

            • 110. Park DP, Ayres JG, McLeod DT, et al. Vocal cord dysfunction treated with long-term tracheostomy: 2 case studies. Ann Allergy Asthma Immunol. 2007;98:591-594.[Abstract]

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