Highlights & Basics
- Sjogren syndrome is a chronic inflammatory and autoimmune disorder characterized by diminished lacrimal and salivary gland secretion (sicca complex).
- May present with fatigue and dry eyes (keratoconjunctivitis sicca) and dry mouth (xerostomia).
- Diagnosed by positive antinuclear antibodies, anti-60 kD (SS-A) Ro and anti-La autoantibodies, decreased saliva and tear production, lymphocytic infiltration in labial salivary gland biopsy.
- Treatment is mainly symptomatic.
Quick Reference
History & Exam
Key Factors
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Diagnostics Tests
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Definition
Epidemiology
Etiology
Pathophysiology
Citations
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