Type 1 diabetes mellitus - Symptoms, Causes, Images, and Treatment Options

Diseases

Highlights & Basics

Key Highlights

Type 1 diabetes mellitus is a metabolic disorder characterized by hyperglycemia due to absolute insulin deficiency.
Patients most often present with a few days or weeks of polyuria, polydipsia, weight loss, and weakness.
Some patients may present with diabetic ketoacidosis.
Insulin is required for the treatment of type 1 diabetes.
Intensive glycemic control has been shown to decrease the incidence of microvascular and macrovascular complications.

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Definition

Epidemiology

Etiology

Pathophysiology

Citations

Key Articles

American Diabetes Association. Standards of care in diabetes - 2024. Diabetes Care. 2024 Jan;47(1):S1-321.[Full Text]
Norris JM, Johnson RK, Stene LC. Type 1 diabetes-early life origins and changing epidemiology. Lancet Diabetes Endocrinol. 2020 Mar;8(3):226-38.[Abstract][Full Text]
Chiang JL, Maahs DM, Garvey KC, et al. Type 1 diabetes in children and adolescents: a position statement by the American Diabetes Association. Diabetes Care. 2018 Aug 9;41(9):2026-44.[Abstract][Full Text]

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Referenced Articles

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