Highlights & Basics
- Animal bites that most commonly require medical attention include those inflicted by dogs, cats, or humans.
- Description of the circumstances surrounding the bite (i.e., type and behavior of animal) is essential.
- Surgical exploration is important, particularly in wounds that are deep or wide or that potentially involve deep anatomical structures.
- Cultures may be helpful if signs of infection are present.
- Antibiotics are recommended for infected animal bites and, in certain circumstances, noninfected animal bites.
Quick Reference
History & Exam
Key Factors
Other Factors
Diagnostics Tests
Treatment Options
Definition
Epidemiology
Etiology
Pathophysiology
Citations
Rao AK, Briggs D, Moore SM, et al. Use of a modified preexposure prophylaxis vaccination schedule to prevent human rabies: recommendations of the Advisory Committee on Immunization Practices - United States, 2022. MMWR Morb Mortal Wkly Rep. 2022 May 6;71(18):619-27.[Abstract][Full Text]
Stevens DL, Bisno AL, Chambers HF, et al. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clin Infect Dis. 2014 Jul 15;59(2):e10-52.[Abstract][Full Text]
National Institute for Health and Care Excellence. Human and animal bites: antimicrobial prescribing. November 2020 [internet publication].[Full Text]
Centers for Disease Control and Prevention. Advisory Committee on Immunization Practices recommended immunization schedule for children and adolescents ages 18 years or younger, United States, 2024. Nov 2023 [internet publication].[Full Text]
Centers for Disease Control and Prevention. Advisory Committee on Immunization Practices recommended immunization schedule for adults ages 19 years or older, United States, 2024. Nov 2023 [internet publication].[Full Text]
1. Jakeman M, Oxley JA, Owczarczak-Garstecka SC, et al. Pet dog bites in children: management and prevention. BMJ Paediatr Open. 2020;4(1):e000726.[Abstract][Full Text]
2. Tulloch JSP, Owczarczak-Garstecka SC, Fleming KM, et al. English hospital episode data analysis (1998-2018) reveal that the rise in dog bite hospital admissions is driven by adult cases. Sci Rep. 2021 Jan 19;11(1):1767.[Abstract][Full Text]
3. Westgarth C, Brooke M, Christley RM. How many people have been bitten by dogs? a cross-sectional survey of prevalence, incidence and factors associated with dog bites in a UK community. J Epidemiol Community Health. 2018 Apr;72(4):331-6.[Abstract][Full Text]
4. Tulloch JSP, Oxley JA, Christley RM, et al. Dog-related deaths registered in England and Wales from 2001 to 2021. Public Health. 2023 Feb;215:91-3.[Abstract][Full Text]
5. Waters A. Rising fatalities, injuries, and NHS costs: dog bites as a public health problem. BMJ. 2023 Apr 27;381:879.
6. World Health Organization. Animal bites. Feb 2018 [internet publication].[Full Text]
7. Loder RT. The demographics of dog bites in the United States. Heliyon. 2019 Mar;5(3):e01360.[Abstract][Full Text]
8. Centers for Disease Control and Prevention. QuickStats: number of deaths resulting from being bitten or struck by a dog,* by sex - National Vital Statistics System, United States, 2011-2021. Sep 2023 [internet publication].[Full Text]
9. Sarenbo S, Svensson PA. Bitten or struck by dog: a rising number of fatalities in Europe, 1995-2016. Forensic Sci Int. 2021 Jan;318:110592.[Abstract][Full Text]
10. Colmers-Gray IN, SP Tulloch JSP, Dostaler G, et al. Management of mammalian bites. BMJ. 2023 Feb 02;380:e071921.
11. Langley R, Haskell MG, Hareza D, et al. Rodent bite injuries presenting to emergency departments in the United States, 2001-2015. J Environ Health. 2021 Mar;83(7):18-24.
12. Freeman AJ, Senn DR, Arendt DM. Seven hundred seventy eight bite marks: analysis by anatomic location, victim and biter demographics, type of crime, and legal disposition. J Forensic Sci. 2005 Nov;50(6):1436-43.[Abstract]
13. Kennedy SA, Stoll LE, Lauder AS. Human and other mammalian bite injuries of the hand: evaluation and management. J Am Acad Orthop Surg. 2015 Jan;23(1):47-57.[Abstract][Full Text]
14. Greene SE, Fritz SA. Infectious complications of bite injuries. Infect Dis Clin North Am. 2021 Mar;35(1):219-36.[Abstract]
15. Talan DA, Citron DM, Abrahamian FM, et al. Bacteriologic analysis of infected dog and cat bites. N Engl J Med. 1999 Jan 14;340(2):85-92.[Abstract][Full Text]
16. Abrahamian FM, Goldstein EJ. Microbiology of animal bite wound infections. Clin Microbiol Rev. 2011 Apr;24(2):231-46.[Abstract][Full Text]
17. Talan DA, Abrahamian FM, Moran GJ, et al. Clinical presentation and bacteriologic analysis of infected human bites in patients presenting to emergency departments. Clin Infect Dis. 2003 Dec 1;37(11):1481-9.[Abstract][Full Text]
18. Manning SE, Rupprecht CE, Fishbein D, et al. Advisory Committee on Immunization Practices Centers for Disease Control and Prevention (CDC). Human rabies prevention - United States, 2008: recommendations of the Advisory Committee on Immunization Practices. MMWR Recomm Rep. 2008 May 23;57(RR-3):1-28.[Abstract][Full Text]
19. Goldstein EJ. Bite wounds and infection. Clin Infect Dis. 1992 Mar;14(3):633-8.[Abstract]
20. Smith PF, Meadowcroft AM, May DB. Treating mammalian bite wounds. J Clin Pharm Ther. 2000 Apr;25(2):85-99.[Abstract]
21. Morgan M. Hospital management of animal and human bites. J Hosp Infect. 2008 May 23;57(RR-3):1-28.[Abstract]
22. Griego RD, Rosen T, Orengo IF, et al. Dog, cat, and human bites: a review. J Am Acad Dermatol. 1995 Dec;33(6):1019-29.[Abstract]
23. Abrahamian FM. Dog bites: bacteriology, management and prevention. Curr Infect Dis Rep. 2000 Oct;2(5):446-53.[Abstract]
24. American Academy of Pediatrics. Bite wounds. In: Kimberlin DW, Barnett ED, Lynfield R, et al (eds). Red Book: 2021 report of the Committee on Infectious Diseases. American Academy of Pediatrics; 2021; 169-75.
25. Plana NM, Kalmar CL, Cheung L, et al. Pediatric dog bite injuries: a 5-Year nationwide study and implications of the COVID-19 pandemic. J Craniofac Surg. 2022 Jul-Aug 01;33(5):1436-40.[Abstract]
26. Lee CJ, Tiourin E, Schuljak S, et al. Surgical treatment of pediatric dog-bite wounds: a 5-year retrospective review. West J Emerg Med. 2021 Oct 27;22(6):1301-10.[Abstract][Full Text]
27. Sacks JJ, Kresnow M, Houston B. Dog bites: how big a problem? Inj Prev. 1996 Mar;2(1):52-4.[Abstract]
28. Rao AK, Briggs D, Moore SM, et al. Use of a modified preexposure prophylaxis vaccination schedule to prevent human rabies: recommendations of the Advisory Committee on Immunization Practices - United States, 2022. MMWR Morb Mortal Wkly Rep. 2022 May 6;71(18):619-27.[Abstract][Full Text]
29. World Health Organization. Weekly epidemiological record. Rabies vaccines: WHO position paper. April 2018 [internet publication].[Full Text]
30. Leone G, Pizzigallo E. Bacterial infections following splenectomy for malignant and nonmalignant hematologic diseases. Mediterr J Hematol Infect Dis. 2015 Oct 13;7(1):e2015057.[Abstract][Full Text]
31. Morgan M, Palmer J. Dog bites. BMJ. 2007 Feb 24;334(7590):413-7.[Full Text]
32. Mensa M, Cubitt JJ, Javed M, et al. Dog bites and diabetic peripheral neuropathy: a dangerous combination. BMJ Case Rep. 2017 Sep 23;2017.[Abstract]
33. Oya J, Hanai K, Miura J, et al. Diabetic gangrene in multiple fingers and toes after a dog bite in an elderly patient with type 2 diabetes. Intern Med. 2011;50(12):1303-7.[Abstract][Full Text]
34. Lee S, Roh KH, Kim CK, et al. A case of necrotizing fasciitis due to streptococcus agalactiae, arcanobacterium haemolyticum, and finegoldia magna in a dog-bitten patient with diabetes. Korean J Lab Med. 2008 Jun;28(3):191-5.[Abstract]
35. American Veterinary Medical Association Task Force on Canine Aggression and Human-Canine Interactions: a community approach to dog bite prevention. J Am Vet Med Assoc. 2001 Jun 1;218(11):1732-49.[Abstract]
36. Shen J, Rouse J, Godbole M, et al. Systematic review: interventions to educate children about dog safety and prevent pediatric dog-bite injuries: a meta-analytic review. J Pediatr Psychol. 2017 Aug 1;42(7):779-91. [Abstract][Full Text]
37. Presutti RJ. Prevention and treatment of dog bites. Am Fam Physician. 2001 Apr 15;63(8):1567-72.[Abstract][Full Text]
38. Centers for Disease Control and Prevention. CDC Yellow Book 2024: health information for international travel. Section 5: travel-associated infections & diseases - rabies. May 2023 [internet publication].[Full Text]
39. Ellis R, Ellis C. Dog and cat bites. Am Fam Physician. 2014 Aug 15;90(4):239-43. [Abstract][Full Text]
40. Evgeniou E, Markeson D, Iyer S, et al. The management of animal bites in the United kingdom. Eplasty. 2013 Jun 10;13:e27.[Abstract][Full Text]
41. Centres for Disease Control and Prevention. Rabies postexposure prophylaxis (PEP): what medical care will I receive if I may have been exposed to rabies? May 2022 [internet publication].[Full Text]
42. Stevens DL, Bisno AL, Chambers HF, et al. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clin Infect Dis. 2014 Jul 15;59(2):e10-52.[Abstract][Full Text]
43. Xiaowei Z, Wei L, Xiaowei H, et al. Comparison of primary and delayed wound closure of dog-bite wounds. Vet Comp Orthop Traumatol. 2013;26(3):204-7.[Abstract]
44. Rui-feng C, Li-song H, Ji-bo Z, et al. Emergency treatment on facial laceration of dog bite wounds with immediate primary closure: a prospective randomized trial study. BMC Emerg Med. 2013;13(suppl 1):S2.[Abstract][Full Text]
45. Paschos NK, Makris EA, Gantsos A, et al. Primary closure versus non-closure of dog bite wounds. A randomised controlled trial. Injury. 2014 Jan;45(1):237-40.[Abstract]
46. Chen E, Hornig S, Shepherd SM, et al. Primary closure of mammalian bites. Acad Emerg Med. 2000 Feb;7(2):157-61.[Abstract]
47. Bhaumik S, Kirubakaran R, Chaudhuri S. Primary closure versus delayed or no closure for traumatic wounds due to mammalian bite. Cochrane Database Syst Rev. 2019 Dec 6;12(12):CD011822.[Abstract][Full Text]
48. Callaham M. Prophylactic antibiotics in dog bite wounds: nipping at the heels of progress. Ann Emerg Med. 1994 Mar;23(3):577-9.[Abstract]
49. Cummings P. Antibiotics to prevent infection in patients with dog bite wounds: a meta-analysis of randomized trials. Ann Emerg Med. 1994 Mar;23(3):535-40.[Abstract]
50. Jones N, Khoosal M. Infected dog and cat bites. N Engl J Med. 1999 Jun 10;340(23):1841.[Abstract]
51. Mederios I, Saconato H. Antibiotic prophylaxis for mammalian bites. Cochrane Database Syst Rev. 2001;(2):CD001738.[Abstract]
52. Henton J, Jain A. Cochrane corner: antibiotic prophylaxis for mammalian bites (intervention review). J Hand Surg Eur Vol. 2012 Oct;37(8):804-6.[Abstract]
53. National Institute for Health and Care Excellence. Human and animal bites: antimicrobial prescribing. November 2020 [internet publication].[Full Text]
54. Dendle C, Looke D. Management of mammalian bites. Aust Fam Physician. 2009 Nov;38(11):868-74.[Abstract][Full Text]
55. The British Association for Forensic Odontology. Management of injuries caused by teeth. May 2021 [internet publication].[Full Text]
56. Centers for Disease Control and Prevention. CDC Yellow Book 2024: health information for international travel. Section 5: travel-associated infections & diseases - tetanus. May 2023 [internet publication].[Full Text]
57. Centres for Disease Control and Prevention. Rabies: medical care. June 2018 [internet publication].[Full Text]
58. European Medicines Agency. Quinolone- and fluoroquinolone-containing medicinal products. Mar 2019 [internet publication].[Full Text]
59. Food and Drug Administration. FDA Drug Safety Communication. FDA warns about increased risk of ruptures or tears in the aorta blood vessel with fluoroquinolone antibiotics in certain patients. December 2018 [internet publication].[Full Text]
60. Food and Drug Administration. FDA Drug Safety Communication. FDA reinforces safety information about serious low blood sugar levels and mental health side effects with fluoroquinolone antibiotics; requires label changes. July 2018 [internet publication].[Full Text]
61. Rui-Feng C, Li-Song H, Ji-Bo Z, et al. Negative pressure wound therapy for serious dog bites of extremities: a prospective randomized trial. Am J Emerg Med. 2016 Jun;34(6):1006-10.[Abstract]
62. Iheozor-Ejiofor Z, Newton K, Dumville JC, et al. Negative pressure wound therapy for open traumatic wounds. Cochrane Database Syst Rev. 2018 Jul 3;(7):CD012522.[Abstract][Full Text]
63. Singletary EM, Zideman DA, Bendall JC, et al. 2020 International consensus on first aid science with treatment recommendations. Circulation. 2020 Oct 20;142(16_suppl_1):S284-S334.[Abstract][Full Text]
64. Liang JL, Tiwari T, Moro P, et al. Prevention of pertussis, tetanus, and diphtheria with vaccines in the United States: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2018 Apr 27;67(2):1-44. [Abstract][Full Text]
65. Rupprecht CE, Briggs D, Brown CM, et al; Centers for Disease Control and Prevention. Use of a reduced (4-dose) vaccine schedule for postexposure prophylaxis to prevent human rabies: recommendations of the Advisory Committee on Immunization Practices. MMWR Recomm Rep. 2010 Mar 19;59(RR-2):1-9.[Abstract][Full Text]
66. Centers for Disease Control and Prevention. Advisory Committee on Immunization Practices recommended immunization schedule for children and adolescents ages 18 years or younger, United States, 2024. Nov 2023 [internet publication].[Full Text]
67. Centers for Disease Control and Prevention. Advisory Committee on Immunization Practices recommended immunization schedule for adults ages 19 years or older, United States, 2024. Nov 2023 [internet publication].[Full Text]
68. Ji L, Xiaowei Z, Chuanlin W, et al. Investigation of posttraumatic stress disorder in children after animal-induced injury in China. Pediatrics. 2010 Aug;126(2):e320-4.[Abstract]
69. National Institute for Health and Care Excellence. Post-traumatic stress disorder. Dec 2018 [internet publication].[Full Text]
70. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders (DSM-5-TR). 2023 [internet publication].[Full Text]
71. Duperrex O, Blackhall K, Burri M, et al. Education of children and adolescents for the prevention of dog bite injuries. Cochrane Database Syst Rev. 2009;(2):CD004726.[Abstract]
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