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Diseases

Pleural effusion

OVERVIEW

  • Highlights & Basics
  • Images

DIAGNOSIS

  • Diagnostic Approach
  • Risk Factors
  • History & Exam
  • Tests
  • Differential Diagnosis
  • Criteria
  • Screening

TREATMENT

  • Tx Approach
  • Tx Options
  • Emerging Tx
  • Prevention

FOLLOW-UP

  • Overview
  • Complications

REFERENCES

  • Citations
  • Guidelines
  • Credits

PATIENT RESOURCES

  • Patient Instructions

Highlights & Basics

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Key Highlights
  • Pleural effusion predominantly presents with breathlessness, but cough and pleuritic chest pain can be a feature. The etiology of the pleural effusion determines other signs and symptoms.

  • Diagnosis of pleural effusion involves clinical evaluation, imaging studies (chest x-ray, ultrasound, computed tomography) pleural fluid analysis (biochemistry, cytology, culture), and establishing the nature of the effusion and the underlying cause.

  • The patient's history and physical exam should guide workup. Early diagnosis is important to minimize invasive interventions and to identify serious underlying conditions, such as malignancy.

  • Treatment is based on the nature of the effusion and underlying condition.

  • Therapeutic thoracentesis with nearly complete removal of the fluid collection alleviates dyspnea and cough in most circumstances.

Left-sided pleural effusion
Left-sided pleural effusion
From the collection of R Light

Quick Reference

  • History & Exam

    • Key Factors

      • Other Factors

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      • Diagnostics Tests

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        • Treatment Options

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          Definition

          Epidemiology

          Etiology

          Pathophysiology

          content by BMJ Group
          Last updated

          Images

          • Left-sided pleural effusion

            Left-sided pleural effusion

          Citations

            Key Articles

            • Feller-Kopman D, Light R. Pleural Disease. N Engl J Med. 2018 Feb 22;378(8):740-751.

            • Roberts ME, Rahman NM, Maskell NA, et al. British Thoracic Society Guideline for pleural disease. Thorax. 2023 Jul;78(suppl 3):s1-42.[Full Text]

            • Sundaralingam A, Grabczak EM, Burra P, et al. ERS statement on benign pleural effusions in adults. Eur Respir J. 2024 Dec;64(6):2302307.[Abstract][Full Text]

            • Expert Panel on Thoracic Imaging, Morris MF, Henry TS, et al. ACR Appropriateness Criteria® workup of pleural effusion or pleural Disease. J Am Coll Radiol. 2024 Jun;21(6):S343-52.[Abstract]

            • Bibby AC, Dorn P, Psallidas I, et al. ERS/EACTS statement on the management of malignant pleural effusions. Eur Respir J. 2018 Jul;52(1):1800349.[Abstract][Full Text]

            • Feller-Kopman DJ, Reddy CB, DeCamp MM, et al. Management of malignant pleural effusions. An official ATS/STS/STR clinical practice guideline. Am J Respir Crit Care Med. 2018 Oct 1;198(7):839-49.[Abstract][Full Text]

            Referenced Articles

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