Highlights & Basics
- Mitral valve prolapse is the most common cause of chronic mitral regurgitation in developed countries.
- One or both leaflets prolapse into the left atrium during systole.
- Diagnosis is established by clinical exam and echocardiography.
- Usually follows a benign course with a favorable prognosis.
- Uncommonly, serious complications occur such as infective endocarditis, severe mitral regurgitation, or sudden cardiac death. Patients at increased risk are identifiable by clinical and echocardiographic features.
Quick Reference
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Citations
Otto CM, Nishimura RA, Bonow RO, et al. 2020 ACC/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2021 Feb 2;143(5):e72-e227.[Abstract][Full Text]
Delgado V, Ajmone Marsan N, de Waha S, et al. 2023 ESC guidelines for the management of endocarditis. Eur Heart J. 2023 Oct 14;44(39):3948-4042.[Full Text]
Vahanian A, Beyersdorf F, Praz F, et al. 2021 ESC/EACTS guidelines for the management of valvular heart disease. Eur Heart J. 2021 Aug 28:ehab395.[Abstract][Full Text]
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