epocrates logo
epocrates logo
epocrates logo
  • 0

Diseases

Tapeworm infection

OVERVIEW

  • Highlights & Basics
  • Images

DIAGNOSIS

  • Diagnostic Approach
  • Risk Factors
  • History & Exam
  • Tests
  • Differential Diagnosis
  • Criteria
  • Screening

TREATMENT

  • Tx Approach
  • Tx Options
  • Emerging Tx
  • Prevention

FOLLOW-UP

  • Overview
  • Complications

REFERENCES

  • Citations
  • Guidelines
  • Credits

PATIENT RESOURCES

  • Patient Instructions

Highlights & Basics

AAFont SizeShareMore Information
Key Highlights
  • Tapeworm infection mainly affects communities in developing countries of Latin America, Asia, and Africa.

  • Presentation is variable and is dependent on the number, size, location, stage, and condition of the cyst. Extraintestinal manifestations include cysticercosis (can affect any organ), hydatidosis (can affect any organ but typically the liver and lungs), and neurocysticercosis (affecting the central nervous system).

  • Diagnosis is made by stool examination and serology; imaging is necessary for extraintestinal manifestations.

  • Intestinal infection is treated with antiparasitic therapy only, while extraintestinal infection requires additional treatments including corticosteroids, anticonvulsants, and possibly surgical intervention. Patients with neurocysticercosis may present with increased intracranial pressure, which is a medical emergency.

Adult tapeworm identified as Taenia saginata
Adult tapeworm identified as Taenia saginata
From the personal collections of Dr Christina Coyle and Dr Maheen Saeed; used with permission

Quick Reference

  • History & Exam

    • Key Factors

      • Other Factors

        More information...
      • Diagnostics Tests

          More information...
        • Treatment Options

            More information...

          Definition

          Epidemiology

          Etiology

          Pathophysiology

          content by BMJ Group
          Last updated

          Images

          • Adult tapeworm identified as Taenia saginata

            Adult tapeworm identified as Taenia saginata

          • Echinococcus of liver with daughter cyst on ultrasound: multivesicular, multiseptated cysts, where d

            Echinococcus of liver with daughter cyst on ultrasound: multivesicular, multiseptated cysts, where daughter cyst completely fills the unilocular mother cyst; cyst produces a wheel-like structure

          • Colloidal stage - neurocysticercosis: CT scan showing ring enhancing cystic lesion in the temporal l

            Colloidal stage - neurocysticercosis: CT scan showing ring enhancing cystic lesion in the temporal lobe and perilesional edema

          • Cystic stage - neurocysticercosis: MRI scan showing cystic lesion in the frontal lobe; a scolex can

            Cystic stage - neurocysticercosis: MRI scan showing cystic lesion in the frontal lobe; a scolex can be seen within the cyst

          • Granular stage - neurocysticercosis: MRI scan showing enhancing lesion without perilesional edema

            Granular stage - neurocysticercosis: MRI scan showing enhancing lesion without perilesional edema

          • Calcified stage - neurocysticercosis: MRI scan of multiple calcified lesions in a patient with neuro

            Calcified stage - neurocysticercosis: MRI scan of multiple calcified lesions in a patient with neurocysticercosis

          Citations

            Key Articles

            • World Health Organization. WHO guidelines for the treatment of patients with cystic echinococcosis. Jun 2025 [internet publication].​[Full Text]

            • White AC Jr, Coyle CM, Rajshekhar V, et al. Diagnosis and treatment of neurocysticercosis: 2017 clinical practice guidelines by the Infectious Diseases Society of America (IDSA) and the American Society of Tropical Medicine and Hygiene (ASTMH). Clin Infect Dis. 2018 Apr 3;66(8):e49-75.[Abstract][Full Text]

            • World Health Organization. ​WHO guidelines on management of Taenia solium neurocysticercosis. Sep 2021 [internet publication].[Full Text]

            • Del Brutto OH, Nash TE, White AC Jr, et al. Revised diagnostic criteria for neurocysticercosis. J Neurol Sci. 2017 Jan 15;372:202-10.[Abstract][Full Text]

            Other Online Resources

            • ​WHO Taenia solium endemicity map - 2022 update
            • CDC: about human tapeworm
            • CDC: about cysticercosis
            • WHO: taeniasis/cysticercosis - fact sheet
            • WHO: echinococcosis - fact sheet​

            Referenced Articles

            • 1. Schantz PM, Kern P, Brunetti R. Echinococcus. In: Guerrant RL, Walker DH, Weller PF, eds. Tropical infectious diseases: principles, pathogens and practice. 1st ed. Oxford, UK: Churchill Livingstone; 2005:1304-26.

            • 2. Wittner M, Tanowitz HB, White AC. Taenia and other tapeworms. In: Guerrant RL, Walker DH, Weller PF, eds. Tropical infectious diseases: principles, pathogens and practice. 1st ed. Oxford, UK: Churchill Livingstone; 2005:1327-40.

            • 3. Centers for Disease Control and Prevention. Human tapeworm (taeniasis): clinical overview of taeniasis​. May 2024 [internet publication].[Full Text]

            • 4. Hernández-Orts JS, Scholz T, Brabec J, et al. High morphological plasticity and global geographical distribution of the Pacific broad tapeworm Adenocephalus pacificus (syn. Diphyllobothrium pacificum): molecular and morphological survey. Acta Trop. 2015 Sep;149:168-78.[Abstract]

            • 5. Garcia HH, del Brutto OH. Taenia solium cysticercosis. Inf Dis Clin North Am. 2000 Mar;14(1):97-119.[Abstract]

            • 6. Verastegui M, Gilman RH, Garcia HH, et al. Prevalence of antibodies to unique Taenia solium onchosphere antigens in Taeniasis and human and porcine cysticercosis. Am J Trop Med Hyg. 2003 Oct;69(4):438-44.[Abstract][Full Text]

            • 7. Gonzalez AE, Garcia HH, Gilman RH, et al. Control of Taenia solium. Acta Trop. 2003 Jun;87(1):103-9.[Abstract]

            • 8. Zoli A, Shey-Njila O, Assana E, et al. Regional status, epidemiology and impact of Taenia solium cysticercosis in Western and Central Africa. Acta Trop. 2003 Jun;87(1):35-42.[Abstract]

            • 9. Centers for Disease Control and Prevention. Human tapeworm (taeniasis)​: about human tapeworm. Jun 2024 [internet publication].[Full Text]

            • 10. Braae UC, Thomas LF, Robertson LJ, et al. Epidemiology of Taenia saginata taeniosis/cysticercosis: a systematic review of the distribution in the Americas. Parasit Vectors. 2018 Sep 20;11(1):518.[Abstract][Full Text]

            • 11. O'Neal SE, Flecker RH. Hospitalization frequency and charges for neurocysticercosis, United States, 2003-2012. Emerg Infect Dis. 2015 Jun;21(6):969-76.[Abstract][Full Text]

            • 12. Balodhi A, Jain K, Gupta P, et al. A meta-analysis on the prevalence of Taenia solium and Taenia saginata infections in India. Trans R Soc Trop Med Hyg. 2023 Aug 3;117(8):539-45.[Abstract]

            • 13. World Health Organization. Taeniasis/cysticercosis: fact sheet. Jan 2022 [internet publication].[Full Text]

            • 14. Laranjo-González M, Devleesschauwer B, Trevisan C, et al. Epidemiology of taeniosis/cysticercosis in Europe, a systematic review: Western Europe. Parasit Vectors. 2017 Jul 21;10(1):349.[Abstract][Full Text]

            • 15. Scholz T, Garcia HH, Kuchta R, et al. Update on the human broad tapeworm (genus diphyllobothrium), including clinical relevance. Clin Microbiol Rev. 2009 Jan;22(1):146-60.[Abstract][Full Text]

            • 16. Khalil HM, el Shimi S, Sarwat MA, et al. Recent study of Hymenolepis nana infection in Egyptian children. J Egypt Soc Parasitol. 1991 Apr;21(1):293-300.[Abstract]

            • 17. Aria HP. Biology of the tapeworm Hymenolepis diminuta. New York, NY: Academic Press; 1980.

            • 18. Biswas H, Arora RR, Sehgal S. Epidemiology of Hymenolepis nana infections in a selected rural community. J Commun Dis. 1978;10(3):170-4.

            • 19. Mason PR, Patterson BA. Epidemiology of Hymenolepis nana infections in primary school children in urban and rural communities in Zimbabwe. J Parasitol. 1994 Apr;80(2):245-50.[Abstract]

            • 20. World Health Organization. WHO guidelines for the treatment of patients with cystic echinococcosis. Jun 2025 [internet publication].​[Full Text]

            • 21. ​World Health Organization. Echinococcosis: fact sheet​. May 2021 [internet publication].​[Full Text]

            • 22. Karshima SN, Ahmed MI, Adamu NB, et al. Africa-wide meta-analysis on the prevalence and distribution of human cystic echinococcosis and canine Echinococcus granulosus infections. Parasit Vectors. 2022 Oct 5;15(1):357.[Abstract][Full Text]

            • 23. Kakamad FH, Anwar KA, Ahmed HK, et al. Risk factors associated with human echinococcosis: a systematic review and meta-analysis. Front Vet Sci. 2024;11:1480579.[Abstract][Full Text]

            • 24. ​Centers for Disease Control and Prevention. Cysticercosis: clinical overview of cysticercosis. Mar 2024 [internet publication].[Full Text]

            • 25. Del Brutto OH, Sotelo J, Roman GC. Neurocysticercosis: a clinical handbook. Lisse, The Netherlands: Swets and Zeitlinger; 1998.

            • 26. Bandres JC, White AC Jr, Samo T, et al. Extraparenchymal neurocysticercosis: report of five cases and review of management. Clin Infect Dis. 1992 Nov;15(5):799-811.[Abstract]

            • 27. Garcia HH, Wittner M, Coyle CM, et al. Cysticercosis. In: Guerrant RL, Walker DH, Weller PF, eds. Tropical infectious diseases: principles, pathogens and practice. 1st ed. Oxford, UK: Churchill Livingstone; 2005:1289-303.

            • 28. Elmonir W, Elaadli H, Amer A, et al. Prevalence of intestinal parasitic infections and their associated risk factors among preschool and school children in Egypt. PLoS One. 2021;16(9):e0258037.[Abstract][Full Text]

            • 29. Gelaw A, Anagaw B, Nigussie B, et al. Prevalence of intestinal parasitic infections and risk factors among schoolchildren at the University of Gondar Community School, Northwest Ethiopia: a cross-sectional study. BMC Public Health. 2013 Apr 5;13:304.[Abstract][Full Text]

            • 30. Openshaw JJ, Medina A, Felt SA, et al. Prevalence and risk factors for Taenia solium cysticercosis in school-aged children: a school based study in western Sichuan, People's Republic of China. PLoS Negl Trop Dis. 2018 May;12(5):e0006465.[Abstract][Full Text]

            • 31. Pan American Health Organization. Guideline for preventive chemotherapy for the control of Taenia solium taeniasis. S​ep 2021 [internet publication]. [Full Text]

            • 32. Garcia HH, Gonzalez AE, Tsang VC, et al. Elimination of Taenia solium transmission in northern Peru. N Engl J Med. 2016 Jun 16;374(24):2335-44.[Abstract][Full Text]

            • 33. World Health Organization. Early detection and management of neurological serious adverse events in relation to the administration of anthelminthic medicines to people with asymptomatic neurocysticercosis. Sep 2023 [internet publication].​[Full Text]

            • 34. Di Lernia V, Ricci C, Albertini G. Skin eruption associated with Hymenolepis nana infection. Int J Dermatol. 2004 May;43(5):357-9.[Abstract]

            • 35. Muehlenbachs A, Bhatnagar J, Agudelo CA, et al. Malignant transformation of Hymenolepis nana in a human host. N Engl J Med. 2015 Nov 5;373(19):1845-52.[Abstract][Full Text]

            • 36. Conn DB. Malignant transformation of Hymenolepis nana in a human host. N Engl J Med. 2016 Mar 31;374(13):1293-4.[Abstract]

            • 37. Saeedan MB, Aljohani IM, Alghofaily KA, et al. Thoracic hydatid disease: a radiologic review of unusual cases. World J Clin Cases. 2020 Apr 6;8(7):1203-12.[Abstract][Full Text]

            • 38. Bumann S, Kuenzli E, Lissandrin R, et al. Cardiac cystic echinococcosis-a systematic review and analysis of the literature. PLoS Negl Trop Dis. 2024 May;18(5):e0012183.[Abstract][Full Text]

            • 39. Aledavoud A, Mohammadi M, Ataei A, et al. Thyroid involvement in cystic echinococcosis: a systematic review. BMC Infect Dis. 2024 Aug 29;24(1):889.[Abstract][Full Text]

            • 40. Rascio L, Donati T, Pascucci D, et al. Rare presentation of echinococcal disease: a systematic review on arterial hydatid cyst. Ann Vasc Surg. 2025 Mar;112:22-31.[Abstract]

            • 41. Cuetter AC, Garcia-Bobadilla J, Guerra LG, et al. Neurocysticercosis: focus on intraventricular disease. Clin Infect Dis. 1997 Feb;24(2):157-64.[Abstract]

            • 42. ​Department of Health, Victoria State Government, Australia. Taeniasis (tapeworm)​. Oct 2015 [internet publication]. [Full Text]

            • 43. White AC Jr, Coyle CM, Rajshekhar V, et al. Diagnosis and treatment of neurocysticercosis: 2017 clinical practice guidelines by the Infectious Diseases Society of America (IDSA) and the American Society of Tropical Medicine and Hygiene (ASTMH). Clin Infect Dis. 2018 Apr 3;66(8):e49-75.[Abstract][Full Text]

            • 44. Centers for Disease Control and Prevention. Cysticercosis: Clinical testing guidance for cysticercosis. Jun 2024 [internet publication].​[Full Text]

            • 45. Proaño-Navarez JV, Meza-Lucas A, Mata-Ruiz O, et al. Laboratory diagnosis of human neurocysticercosis: double-blind comparison of enzyme-linked immunosorbent assay and electroimmunotransfer blot assay. J Clin Microbiol Rev. 2002 Jun;40(6):2115-8.[Abstract][Full Text]

            • 46. World Health Organization. ​WHO guidelines on management of Taenia solium neurocysticercosis. Sep 2021 [internet publication].[Full Text]

            • 47. Webb CM, White AC Jr. Update on the diagnosis and management of neurocysticercosis. Curr Infect Dis Rep. 2016 Dec;18(12):44.[Abstract]

            • 48. Mejia R, Nutman TB. Evaluation and differential diagnosis of marked, persistent eosinophilia. Semin Hematol. 2012 Apr;49(2):149-59.[Abstract][Full Text]

            • 49. Groove D. A history of human helminthology. Wallingford, UK: CAB International; 1990.

            • 50. Garcia HH, Gilman R, Martinez M, et al. Cysticercosis as a major cause of epilepsy in Peru. Lancet. 1993 Jan 23;341(8839):197-200.[Abstract]

            • 51. Del Brutto OH, Nash TE, White AC Jr, et al. Revised diagnostic criteria for neurocysticercosis. J Neurol Sci. 2017 Jan 15;372:202-10.[Abstract][Full Text]

            • 52. Carpio A, Fleury A, Romo ML, et al. New diagnostic criteria for neurocysticercosis: reliability and validity. Ann Neurol. 2016 Sep;80(3):434-42.[Abstract][Full Text]

            • 53. World Health Organization. Expert consensus for the diagnosis and treatment of cystic and alveolar echinococcosis in humans​. Nov 2009 [internet publication].[Full Text]

            • 54. ​Centers for Disease Control and Prevention. CDC Yellow Book 2026: health information for international travel. Section 10: travel-associated infections & diseases - post-travel parasitic disease including evaluation of eosinophilia. Apr 2025 [internet publication].[Full Text]

            • 55. White AC Jr, Garcia HH. Updates on the management of neurocysticercosis. Curr Opin Infect Dis. 2018 Oct;31(5):377-82.[Abstract]

            • 56. ​Centers for Disease Control and Prevention. Human tapeworm (taeniasis): clinical treatment of taeniasis​. May 2024 [internet publication].[Full Text]

            • 57. ​​Centers for Disease Control and Prevention. Cysticercosis: clinical care of cysticercosis. Mar 2024 [internet publication].[Full Text]

            • 58. Proaňo JV, Madrazo I, Avelar F, et al. Medical treatment for neurocysticercosis characterized by giant subarachnoid cysts. N Engl J Med. 2001 Sep 20;345(12):879-85.[Abstract][Full Text]

            • 59. Mitre E, Talaat KR, Sperling MR, et al. Methotrexate as a corticosteroid-sparing agent in complicated neurocysticercosis. Clin Infect Dis. 2007 Feb 15;44(4):549-53.[Abstract]

            • 60. Garg RK, Rizvi I, Nigam H, et al. Treatment outcome in patients with spinal neurocysticercosis: a systematic review of published cases and case series. Future Microbiol. 2025 Jan;20(1):45-56.[Abstract][Full Text]

            • 61. Garcia HH, Lescano AG, Gonzales I, et al. Cysticidal efficacy of combined treatment with praziquantel and albendazole for parenchymal brain cysticercosis. Clin Infect Dis. 2016 Jun 1;62(11):1375-9.[Abstract]

            • 62. Garcia HH, Gonzales I, Lescano AG, et al. Efficacy of combined antiparasitic therapy with praziquantel and albendazole for neurocysticercosis: a double-blind, randomised controlled trial. Lancet Infect Dis. 2014 Aug;14(8):687-95.[Abstract]

            • 63. Dewi DAR, Irawati Tjahjo Widuri L, Allatib A, et al. Effectiveness of the antiparasitic combination of albendazole and praziquantel as compared with albendazole monotherapy in the treatment of neurocysticercosis in children: a systematic review and meta-analysis. Cureus. 2024 Jul;16(7):e64617.[Abstract][Full Text]

            • 64. Monk E, Abba K, Ranganathan L. Anthelmintics for people with neurocysticercosis. Cochrane Database Syst Rev. 2021 Jun 1;6(6):CD000215.[Abstract][Full Text]

            • 65. Walton D, Castell H, Collie C, et al. Antiepileptic drugs for seizure control in people with neurocysticercosis. Cochrane Database Syst Rev. 2021 Nov 1;11(11):CD009027.[Abstract][Full Text]

            • 66. Garcia HH, Gonzales I, Lescano AG, et al. Enhanced steroid dosing reduces seizures during antiparasitic treatment for cysticercosis and early after. Epilepsia. 2014 Sep;55(9):1452-9.[Abstract][Full Text]

            • 67. Khuroo MS, Wani NA, Javid G, et al. Percutaneous drainage compared with surgery for hepatic hydatid cysts. N Engl J Med. 1997 Sep 25;337(13):881-7.[Abstract][Full Text]

            • 68. Smego RA Jr, Bhatti S, Khaliq AA, et al. Percutaneous aspiration-injection-reaspiration drainage plus albendazole or mebendazole for hepatic cystic echinococcosis: a meta-analysis. Clin Infect Dis. 2003 Oct 15;37(8):1073-83.[Abstract]

            • 69. Kuehn R, Uchiumi LJ, Tamarozzi F. Treatment of uncomplicated hepatic cystic echinococcosis (hydatid disease). Cochrane Database Syst Rev. 2024 Jul 12;7(7):CD015573.[Abstract][Full Text]

            • 70. An G, Murry DJ, Gajurel K, et al. Pharmacokinetics, safety, and tolerability of oxfendazole in healthy volunteers: a randomized, placebo-controlled first-in-human single-dose escalation study. Antimicrob Agents Chemother. 2019 Apr;63(4):e02255-18.[Abstract][Full Text]

            • 71. Bach T, Galbiati S, Kennedy JK, et al. Pharmacokinetics, safety, and tolerability of oxfendazole in healthy adults in an open-label phase 1 multiple ascending dose and food effect study. Antimicrob Agents Chemother. 2020 Oct 20;64(11):e01018-20.[Abstract][Full Text]

            • 72. ClinicalTrials.gov. Oxfendazole in mild parenchymal brain cysticercosis. ClinicalTrials.gov Identifier: NCT06565507. Nov 2024 [internet publication].​[Full Text]

            • 73. Alzoubi M, Daradkeh S, Daradka K, et al. The recurrence rate after primary resection cystic echinococcosis: a meta-analysis and systematic literature review. Asian J Surg. 2024 Sep 28:S1015-9584(24)02081-5.[Abstract][Full Text]

            • 74. The Medical Letter. Drugs for parasitic infections. New Rochelle, NY: The Medical Letter; 2007.

          Have feedback?
          Tell us about your experience
          Scroll to Top
          epocrates logo

          Sign in to access our clinical decision support tools

          Sign inCreate Account
          Download Epocrates from the App StoreDownload Epocrates from the Play Store
          About UsFeaturesBusiness SolutionsHelp & Feedback
          © 2026 epocrates, Inc.   Terms of UsePrivacy PolicyEditorial PolicyDo Not Sell or Share My Information