Highlights & Basics
- Acute otitis externa (AOE) is a diffuse inflammation of the external ear canal that is most commonly caused by Pseudomonas aeruginosa and Staphylococcus aureus.
- Presents with rapid onset of ear pain, tenderness, itching, aural fullness, and hearing loss.
- More common in children and young adults.
- Fungal otitis externa is a fungal infection of the external ear caused by molds and yeasts, which presents in a similar way to acute bacterial otitis externa.
- Necrotizing otitis externa infection (also called malignant otitis externa) involves skin and soft tissue of the external auditory canal and bone tissue of the temporal bone.
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Citations
Rosenfeld RM, Schwartz SR, Cannon CR, et al. American Academy of Otolaryngology-Head and Neck Surgery Foundation. Clinical practice guideline: acute otitis externa. Otolaryngol Head Neck Surg. 2014 Feb;150(1 suppl):S1-24. [Erratum in: Otolaryngol Head Neck Surg. 2014 Mar;150(3):504].[Abstract][Full Text]
Hirsch BE. Infections of the external ear. Am J Otolaryngol. 1992 May-Jun;13(3):145-55.[Abstract]
Jackson EA, Geer K. Acute otitis externa: rapid evidence review. Am Fam Physician. 2023 Feb;107(2):145-51.[Abstract]
Selesnick SH. Otitis externa: management of the recalcitrant case. Am J Otology. 1994 May;15(3):408-12.[Abstract]
1. Rosenfeld RM, Schwartz SR, Cannon CR, et al. American Academy of Otolaryngology-Head and Neck Surgery Foundation. Clinical practice guideline: acute otitis externa. Otolaryngol Head Neck Surg. 2014 Feb;150(1 suppl):S1-24. [Erratum in: Otolaryngol Head Neck Surg. 2014 Mar;150(3):504].[Abstract][Full Text]
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3. Hirsch BE. Infections of the external ear. Am J Otolaryngol. 1992 May-Jun;13(3):145-55.[Abstract]
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13. Selesnick SH. Otitis externa: management of the recalcitrant case. Am J Otology. 1994 May;15(3):408-12.[Abstract]
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35. Mösges R, Schröder T, Baues CM, et al. Dexamethasone phosphate in antibiotic ear drops for the treatment of acute bacterial otitis externa. Curr Med Res Opin. 2008 Aug;24(8):2339-47.[Abstract]
36. Pistorius B, Westberry K, Drehobl M, et al. Prospective, randomized, comparative trial of ciprofloxacin otic drops, with or without hydrocortisone, vs. polymyxin B-neomycin-hydrocortisone otic suspension in the treatment of acute diffuse otitis externa. Infect Dis Clin Pract. 1999;8:387-95.
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44. European Medicines Agency. Quinolone- and fluoroquinolone-containing medicinal products. March 2019 [internet publication].[Full Text]
45. Medicines and Healthcare products Regulatory Agency. Fluoroquinolone antibiotics: new restrictions and precautions for use due to very rare reports of disabling and potentially long-lasting or irreversible side effects. March 2019 [internet publication].[Full Text]
46. US Food and Drug Administration. FDA drug safety communication: FDA updates warnings for oral and injectable fluoroquinolone antibiotics due to disabling side effects. July 2016 [internet publication].[Full Text]
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48. US Food and Drug Administration. FDA drug safety communication: FDA reinforces safety information about serious low blood sugar levels and mental health side effects with fluoroquinolone antibiotics; requires label changes. July 2018 [internet publication].[Full Text]
49. Hopkins ME, Bennett A, Henderson N, et al. A retrospective review and multi-specialty, evidence-based guideline for the management of necrotising otitis externa. J Laryngol Otol. 2020 Jun;134(6):487-92.[Abstract]
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51. Bernstein JM, Holland NJ, Porter GC, et al. Resistance of Pseudomonas to ciprofloxacin: implications for the treatment of malignant otitis externa. J Laryngol Otol. 2007 Feb;121(2):118-23.[Abstract]
52. Sreepada GS, Kwartler JA. Skull base osteomyelitis secondary to malignant otitis externa. Curr Opin Otolaryngol Head Neck Surg. 2003 Oct;11(5):316-23.[Abstract]
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55. Phillips JS, Jones SE. Hyperbaric oxygen as an adjuvant treatment for malignant otitis externa. Cochrane Database Syst Rev. 2013 May 31;(5):CD004617.[Abstract][Full Text]
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