Highlights & Basics
- Ichthyosis is a descriptive term for dry, scaly skin.
- Inherited congenital ichthyoses are a heterogeneous group of disorders. Clinically they are characterized by a wide range of severity, from isolated skin involvement to multiorgan disease. The two most common are ichthyosis vulgaris and X-linked ichthyosis.
- Acquired ichthyosis develops later in life and can be associated with systemic conditions (e.g., lymphoma, diabetes mellitus, systemic lupus erythematosus) or medications.
- Investigations and treatment vary based on the type of ichthyosis that is suspected.
- Newborns with autosomal recessive congenital ichthyosis may be covered with a taut membrane (collodion baby). Management is with aggressive hydration using a humidified chamber and topical lubrication.
Quick Reference
History & Exam
Key Factors
Other Factors
Diagnostics Tests
Treatment Options
Definition
Epidemiology
Etiology
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Citations
Oji V, Traupe H. Ichthyoses: differential diagnosis and molecular genetics. Eur J Dermatol. 2006;16:349-359.[Abstract]
Craiglow BG. Ichthyosis in the newborn. Semin Perinatol. 2013;37:26-31.[Abstract][Full Text]
Shwayder T. Disorders of keratinization: diagnosis and management. Am J Clin Dermatol. 2004;5:17-29.[Abstract]
Vahlquist A, Ganemo A, Virtanen M. Congenital ichthyosis: an overview of current and emerging therapies. Acta Derm Venereol. 2008;88:4-14.[Abstract]
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25. Shwayder T. Disorders of keratinization: diagnosis and management. Am J Clin Dermatol. 2004;5:17-29.[Abstract]
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