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Diseases

Lichen planus

OVERVIEW

  • Highlights & Basics
  • Images

DIAGNOSIS

  • Diagnostic Approach
  • Risk Factors
  • History & Exam
  • Tests
  • Differential Diagnosis
  • Criteria
  • Screening

TREATMENT

  • Tx Approach
  • Tx Options
  • Emerging Tx
  • Prevention

FOLLOW-UP

  • Overview
  • Complications

REFERENCES

  • Citations
  • Guidelines
  • Credits

PATIENT RESOURCES

  • Patient Instructions

Highlights & Basics

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Key Highlights
  • Lichen planus is an idiopathic inflammatory disease affecting the skin, hair, nails, and mucous membranes, usually self-limiting in nature.

  • Characteristic eruption consists of itchy, shiny, flat-topped violaceous papules and plaques favoring the extremities.

  • White net-like patches or ulceration of mucous membranes, nail deformity, scarring alopecia, and other types of skin lesions may also occur.

  • Most patients develop the disease between ages 30 and 60 years.

  • Hepatitis C infection may increase susceptibility, especially to oral disease.

Quick Reference

  • History & Exam

    • Key Factors

      • Other Factors

        More information...
      • Diagnostics Tests

          More information...
        • Treatment Options

            More information...

          Definition

          Epidemiology

          Etiology

          Pathophysiology

          content by BMJ Group
          Last updated

          Images

          • Cutaneous lichen planus

            Cutaneous lichen planus

          • Blaschkoid lichen planus

            Blaschkoid lichen planus

          • Blaschkoid lichen planus

            Blaschkoid lichen planus

          • Inverse lichen planus

            Inverse lichen planus

          • Hypertrophic lichen planus

            Hypertrophic lichen planus

          • Hypertrophic lichen planus

            Hypertrophic lichen planus

          • Oral lichen planus

            Oral lichen planus

          • Genital lichen planus

            Genital lichen planus

          • Lichen planopilaris

            Lichen planopilaris

          • Ungual lichen planus

            Ungual lichen planus

          • Ungual lichen planus

            Ungual lichen planus

          • Zosteriform lichen planus

            Zosteriform lichen planus

          Citations

            Key Articles

            • American College of Obstetricians and Gynecologists. Practice bulletin no. 224: diagnosis and management of vulvar skin disorders. Jul 2020 [internet publication].[Abstract][Full Text]

            • Edwards SK, Bates CM, Lewis F, et al. 2014 UK national guideline on the management of vulval conditions. Int J STD AIDS. 2015 Aug;26(9):611-24.[Abstract]

            • Ioannides D, Vakirlis E, Kemeny L, et al. European S1 guidelines on the management of lichen planus: a cooperation of the European Dermatology Forum with the European Academy of Dermatology and Venereology. J Eur Acad Dermatol Venereol. 2020 Jul;34(7):1403-14.[Abstract][Full Text]

            Other Online Resources

            • ​BAD: oral lichen planus
            • ​BAD: lichen planus

            Referenced Articles

            • 1. Pittelkow MR, Daoud MS. Lichen planus. In: Wolff K, Goldsmith LA, Katz SI, et al, eds. Fitzpatrick's dermatology in general medicine. Vol One. 7th ed. New York, NY: McGraw-Hill Companies, Inc.; 2008:244-255.

            • 2. Boyd AS, Neldner KN. Lichen planus. J Am Acad Dermatol. 1991 Oct;25(4):593-619.[Abstract]

            • 3. Dissemond J. Oral lichen planus: an overview. J Dermatolog Treat. 2004 Jun;15(3):136-40.[Abstract]

            • 4. Goldstein AT, Metz A. Vulvar lichen planus. Clin Obstet Gynecol. 2005 Dec;48(4):818-23.[Abstract]

            • 5. Mehregan DA, Van Hale HM, Muller SA. Lichen planopilaris: clinical and pathologic study of forty-five patients. J Am Acad Dermatol. 1992 Dec;27(6 Pt 1):935-42.[Abstract]

            • 6. Cevasco NC, Bergfeld WF, Remzi BK, et al. A case-series of 29 patients with lichen planopilaris: the Cleveland Clinic Foundation experience on evaluation, diagnosis, and treatment. J Am Acad Dermatol. 2007 Jul;57(1):47-53.[Abstract]

            • 7. Scott MJ Jr, Scott MJ Sr. Ungual lichen planus: lichen planus of the nail. Arch Dermatol. 1979 Oct;115(10):1197-9.[Abstract]

            • 8. Harewood GC, Murray JA, Cameron AJ. Esophageal lichen planus: the Mayo Clinic experience. Dis Esophagus. 1999;12(4):309-11.[Abstract]

            • 9. Ber Rahman S, Ul Bari A, Mumtaz N. Unilateral Blaschkoid lichen planus involving the entire half of the body, a unique presentation. Dermatol Online J. 2007 Jul 13;13(3):36.[Abstract][Full Text]

            • 10. Rajeev S, Veena M, Mithilesh C. Unilateral multiple linear lichen planus along the lines of Blaschko: a report of two cases. Indian J Dermatol Venereol Leprol. 1999;65:225-226.

            • 11. Kabbash C, Laude TA, Weinberg JM, et al. Lichen planus in the lines of Blaschko. Pediatr Dermatol. 2002 Nov-Dec;19(6):541-5.[Abstract]

            • 12. Mohrenschlager M, Engst R, Hein R, et al. Primary manifestations of a zosteriform lichen planus: isotopic response following herpes zoster sine herpete? Br J Dermatol. 2008 May;158(5):1145-6.[Abstract]

            • 13. Kashima A, Tajiri A, Yamashita A, et al. Two Japanese cases of lichen planus pigmentosus-inversus. Int J Dermatol. 2007 Jul;46(7):740-2.[Abstract]

            • 14. Peretz E, Grunwald MH, Halevy S. Annular plaque on the face. Actinic lichen planus (ALP). Arch Dermatol. 1999 Dec;135(12):1543, 1546.[Abstract]

            • 15. Morales-Callaghan A Jr, Martinez G, Aragoneses H, et al. Annular atrophic lichen planus. J Am Acad Dermatol. 2005 May;52(5):906-8.[Abstract]

            • 16. Akay BN, Arslan A, Cekirge S, et al. The first reported case of lichen planus following inactivated influenza vaccination. J Drugs Dermatol. 2007 May;6(5):536-8.[Abstract]

            • 17. Agrawal A, Shenoi SD. Lichen planus secondary to hepatitis B vaccination. Indian J Dermatol Venereol Leprol. 2004 Jul-Aug;70(4):234-5.[Abstract][Full Text]

            • 18. Narasimhan M, Ramakrishnan R, Varri DS, et al. Lichen planus triggered by COVID-19 vaccination: a case series. J Family Med Prim Care. 2024 Jan;13(1):384-7.[Abstract][Full Text]

            • 19. Copeman PW, Schroeter AL, Kierland RR. An unusual variant of lupus erythematosus or lichen planus. Br J Dermatol. 1970 Aug;83(2):269-72.[Abstract]

            • 20. Nagao K, Chen KR. A case of lupus erythematosus/lichen planus overlap syndrome. J Dermatol. 2006 Mar;33(3):187-90.[Abstract]

            • 21. Wagner G, Rose C, Sachse MM. Clinical variants of lichen planus. J Dtsch Dermatol Ges. 2013 Apr;11(4):309-19.[Abstract][Full Text]

            • 22. Schwager Z, Stern M, Cohen J, et al. Clinical epidemiology and treatment of lichen planus: a retrospective review of 2 tertiary care centers. J Am Acad Dermatol. 2019 Dec;81(6):1397-9.[Full Text]

            • 23. Pandhi D, Singal A, Bhattacharya SN. Lichen planus in childhood: a series of 316 patients. Pediatr Dermatol. 2014 Jan-Feb;31(1):59-67.[Abstract]

            • 24. Balasubramaniam P, Ogboli M, Moss C. Lichen planus in children: review of 26 cases. Clin Exp Dermatol. 2008 Jul;33(4):457-9.[Abstract]

            • 25. Schruf E, Biermann MH, Jacob J, et al. Lichen planus in Germany - epidemiology, treatment, and comorbidity. A retrospective claims data analysis. J Dtsch Dermatol Ges. 2022 Aug;20(8):1101-10.[Abstract][Full Text]

            • 26. Bhattacharya A, Kaur I, Kumar B. Lichen planus: a clinical and epidemiological study. J Dermatol. 2000 Sep;27(9):576-82.[Abstract]

            • 27. Li C, Tang X, Zheng X, et al. Global prevalence and incidence estimates of oral lichen planus: a systematic review and meta-analysis. JAMA Dermatol. 2020 Feb 1;156(2):172-81.[Full Text]

            • 28. American College of Obstetricians and Gynecologists. Practice bulletin no. 224: diagnosis and management of vulvar skin disorders. Jul 2020 [internet publication].[Abstract][Full Text]

            • 29. Gupta MK, Lipner SR. Review of nail lichen planus: epidemiology, pathogenesis, diagnosis, and treatment. Dermatol Clin. 2021 Apr;39(2):221-30.[Abstract]

            • 30. Lodi G, Giuliani M, Majorana A, et al. Lichen planus and hepatitis C virus: a multicentre study of patients with oral lesions and a systematic review. Br J Dermatol. 2004 Dec;151(6):1172-81.[Abstract]

            • 31. Yiannias JA, el-Azhary RA, Hand JH, et al. Relevant contact sensitivities in patients with the diagnosis of oral lichen planus. J Am Acad Dermatol. 2000 Feb;42(2 Pt 1):177-82.[Abstract]

            • 32. Li D, Li J, Li C, et al. The association of thyroid disease and oral lichen planus: a literature review and meta-analysis. Front Endocrinol (Lausanne). 2017 Nov 9:8:310.[Abstract][Full Text]

            • 33. Kazandjieva J, Tsankov N. Tattoos: dermatological complications. Clin Dermatol. 2007 Jul-Aug;25(4):375-82.[Abstract]

            • 34. Maul JT, Guillet C, Oschmann A, et al. Cutaneous lichenoid drug eruptions: a narrative review evaluating demographics, clinical features and culprit medications. J Eur Acad Dermatol Venereol. 2023 May;37(5):965-75.[Abstract][Full Text]

            • 35. Sklavounou-Andrikopoulou A, Chrysomali E, Iakovou M, et al. Elevated serum levels of the apoptosis related molecules TNF-alpha, Fas/Apo-1 and Bcl-2 in oral lichen planus. J Oral Pathol Med. 2004 Aug;33(7):386-90.[Abstract]

            • 36. Rhodus NL, Cheng B, Ondrey F. Th1/Th2 cytokine ratio in tissue transudates from patients with oral lichen planus. Mediators Inflamm. 2007;2007:19854.[Abstract][Full Text]

            • 37. Wenzel J , Tuting T. An IFN-associated cytotoxic cellular immune response against viral, self-, or tumor antigens is a common pathogenetic feature in "interface dermatitis". J Invest Dermatol. 2008 Oct;128(10):2392-402.[Abstract]

            • 38. Norris DA. Cytokine modulation of adhesion molecules in the regulation of immunologic cytotoxicity of epidermal targets. J Invest Dermatol. 1990 Dec;95(6 Suppl):111S-120S.[Abstract]

            • 39. Chen X, Liu Z, Yue Q. The expression of TNF-alpha and ICAM-1 in lesions of lichen planus and its implication. J Huazhong Univ Sci Technolog Med Sci. 2007 Dec;27(6):739-41.[Abstract]

            • 40. Bennion SD, Middleton MH, David-Bajar KM, et al. In three types of interface dermatitis, different patterns of expression of intercellular adhesion molecule-1 (ICAM-1) indicate different triggers of disease. J Invest Dermatol. 1995 Jul;105(1 Suppl):71S-79S.[Abstract]

            • 41. Hussein MR. Evaluation of angiogenesis in normal and lichen planus skin by CD34 protein immunohistochemistry: preliminary findings. Cell Biol Int. 2007 Oct;31(10):1292-5.[Abstract]

            • 42. García-Pola M, Rodríguez-Fonseca L, Suárez-Fernández C, et al. Bidirectional association between lichen planus and hepatitis C-an update systematic review and meta-analysis. J Clin Med. 2023 Sep 5;12(18):5777.[Abstract][Full Text]

            • 43. Jin X, Wang J, Zhu L, et al. Association between -308 G/A polymorphism in TNF-alpha gene and lichen planus: a meta-analysis. J Dermatol Sci. 2012 Dec;68(3):127-34.[Abstract]

            • 44. Manolache L, Seceleanu-Petrescu D, Benea V. Lichen planus patients and stressful events. J Eur Acad Dermatol Venereol. 2008 Apr;22(4):437-41.[Abstract]

            • 45. Halevy S, Shai A. Lichenoid drug eruptions. J Am Acad Dermatol. 1993 Aug;29(2 Pt 1):249-55.[Abstract]

            • 46. van der Meijden WI, Boffa MJ, Ter Harmsel B, et al. 2021 European guideline for the management of vulval conditions. J Eur Acad Dermatol Venereol. 2022 Jul;36(7):952-72.[Abstract][Full Text]

            • 47. Tziotzios C, Lee JYW, Brier T, et al. Lichen planus and lichenoid dermatoses: clinical overview and molecular basis. J Am Acad Dermatol. 2018 Nov;79(5):789-804.[Abstract]

            • 48. Asarch A, Gottlieb AB, Lee J, et al. Lichen planus-like eruptions: an emerging side effect of tumor necrosis factor-alpha antagonists. J Am Acad Dermatol. 2009 Jul;61(1):104-11.[Abstract]

            • 49. Vazquez-Lopez F, Gomez-Diez S, Sanchez J, et al. Dermoscopy of active lichen planus. Arch Dermatol. 2007 Aug;143(8):1092.[Abstract]

            • 50. Day T, Wilkinson E, Rowan D, et al. Clinicopathologic diagnostic criteria for vulvar lichen planus. J Low Genit Tract Dis. 2020 Jul;24(3):317-29.[Abstract][Full Text]

            • 51. Edwards SK, Bates CM, Lewis F, et al. 2014 UK national guideline on the management of vulval conditions. Int J STD AIDS. 2015 Aug;26(9):611-24.[Abstract]

            • 52. Kulthanan K, Jiamton S, Varothai S, et al. Direct immunofluorescence study in patients with lichen planus. Int J Dermatol. 2007 Dec;46(12):1237-41.[Abstract]

            • 53. Fellner MJ. Lichen planus. Int J Dermatol. 1980 Mar;19(2):71-5.[Abstract]

            • 54. Weedon D. Skin pathology. 2nd ed. St. Louis, MO: Elsevier Limited; 2002.

            • 55. Ioannides D, Vakirlis E, Kemeny L, et al. European S1 guidelines on the management of lichen planus: a cooperation of the European Dermatology Forum with the European Academy of Dermatology and Venereology. J Eur Acad Dermatol Venereol. 2020 Jul;34(7):1403-14.[Abstract][Full Text]

            • 56. Errichetti E, Figini M, Croatto M, et al. Therapeutic management of classic lichen planopilaris: a systematic review. Clin Cosmet Investig Dermatol. 2018 Feb 27:11:91-102.[Abstract][Full Text]

            • 57. Kellet JK, Ead RD. Treatment of lichen planus with short course of oral prednisolone. Br J Dermatol. 1990 Oct;123(4):550-1.[Abstract]

            • 58. Laurberg G, Geiger JM, Hjorth N, et al. Treatment of lichen planus with acitretin: a double-blind, placebo-controlled study in 65 patients. J Am Acad Dermatol. 1991 Mar;24(3):434-7.[Abstract]

            • 59. Pavlotsky F, Nathansohn N, Kriger G, et al. Ultraviolet-B treatment for cutaneous lichen planus: our experience with 50 patients. Photodermatol Photoimmunol Photomed. 2008 Apr;24(2):83-6.[Abstract]

            • 60. Saricaoglu H, Karadogan SK, Baskan EB, et al. Narrowband UVB therapy in the treatment of lichen planus. Photodermatol Photoimmunol Photomed. 2003 Oct;19(5):265-7.[Abstract]

            • 61. Taneja A, Taylor CR. Narrow-band UVB for lichen planus treatment. Int J Dermatol. 2002 May;41(5):282-3.[Abstract]

            • 62. Gonzalez E, Momtaz-T K, Freedman S. Bilateral comparison of generalized lichen planus treated with psoralens and ultraviolet A. J Am Acad Dermatol. 1984 Jun;10(6):958-61.[Abstract]

            • 63. Husein-ElAhmed H, Gieler U, Steinhoff M. Lichen planus: a comprehensive evidence-based analysis of medical treatment. J Eur Acad Dermatol Venereol. 2019 Oct;33(10):1847-62.[Abstract]

            • 64. Pigatto PD, Chiappino G, Bigardi A, et al. Cyclosporin A for treatment of severe lichen planus. Br J Dermatol. 1990 Jan;122(1):121-3.[Abstract]

            • 65. Ho VC, Gupta AK, Ellis CN, et al. Treatment of severe lichen planus with cyclosporine. J Am Acad Dermatol. 1990 Jan;22(1):64-8.[Abstract]

            • 66. Atzmony L, Reiter O, Hodak E, et al. Treatments for cutaneous lichen planus: a systematic review and meta-analysis. Am J Clin Dermatol. 2016 Feb;17(1):11-22.[Abstract]

            • 67. Assouly P, Reygagne P. Lichen planopilaris: update on diagnosis and treatment. Semin Cutan Med Surg. 2009 Mar;28(1):3-10.[Abstract]

            • 68. Kang H, Alzolibani AA, Otberg N, et al. Lichen planopilaris. Dermatol Ther. 2008 Jul-Aug;21(4):249-56.[Abstract]

            • 69. Chieregato C, Zini A, Barba A, et al. Lichen planopilaris: report of 30 cases and review of the literature. Int J Dermatol. 2003 May;42(5):342-5.[Abstract]

            • 70. Mirmirani P, Willey A, Price VH. Short course of oral cyclosporine in lichen planopilaris. J Am Acad Dermatol. 2003 Oct;49(4):667-71.[Abstract]

            • 71. Tursen U, Api H, Kaya T, et al. Treatment of lichen planopilaris with mycophenolate mofetil. Dermatol Online J. 2004 Jul 15;10(1):24.[Abstract]

            • 72. Scully C, Carrozzo M. Oral mucosal disease: Lichen planus. Br J Oral Maxillofac Surg. 2008 Jan;46(1):15-21.[Abstract]

            • 73. Reddy RL, Reddy RS, Ramesh T, et al. Randomized trial of aloe vera gel vs triamcinolone acetonide ointment in the treatment of oral lichen planus. Quintessence Int. 2012 Oct;43(9):793-800.[Abstract]

            • 74. Davari P, Hsiao HH, Fazel N. Mucosal lichen planus: an evidence-based treatment update. Am J Clin Dermatol. 2014 Jul;15(3):181-95.[Abstract]

            • 75. Sandhu S, Klein BA, Al-Hadlaq M, et al. Oral lichen planus: comparative efficacy and treatment costs-a systematic review. BMC Oral Health. 2022 May 6;22(1):161.[Abstract][Full Text]

            • 76. Lodi G, Manfredi M, Mercadante V, et al. Interventions for treating oral lichen planus: corticosteroid therapies. Cochrane Database Syst Rev. 2020 Feb 28;2(2):CD001168.[Abstract][Full Text]

            • 77. Petruzzi M, Lucchese A, Lajolo C, et al. Topical retinoids in oral lichen planus treatment: an overview. Dermatology. 2013;226(1):61-7.[Abstract]

            • 78. Sun SL, Liu JJ, Zhong B, et al. Topical calcineurin inhibitors in the treatment of oral lichen planus: a systematic review and meta-analysis. Br J Dermatol. 2019 Dec;181(6):1166-76.[Abstract]

            • 79. Mattsson U, Magnusson B, Jontell M. Squamous cell carcinoma in a patient with oral lichen planus treated with topical application of tacrolimus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Jul;110(1):e19-25.[Abstract]

            • 80. Jin X, Lu S, Xing X, et al. Thalidomide: features and potential significance in oral precancerous conditions and oral cancer. J Oral Pathol Med. 2013 May;42(5):355-62.[Abstract]

            • 81. Goldstein AT, Thaci D, Luger T. Topical calcineurin inhibitors for the treatment of vulvar dermatoses. Eur J Obstet Gynecol Reprod Biol. 2009 Sep;146(1):22-9. [Abstract]

            • 82. Iorizzo M, Tosti A, Starace M, et al. Isolated nail lichen planus: an expert consensus on treatment of the classical form. J Am Acad Dermatol. 2020 Dec;83(6):1717-23.[Abstract]

            • 83. Tosti A, Peluso AM, Fanti PA, et al. Nail lichen planus: clinical and pathological study of twenty-four patients. J Am Acad Derm. 1993 May;28(5 Pt 1):724-30.[Abstract]

            • 84. Goulden V, Ling TC, Babakinejad P, et al. British Association of Dermatologists and British Photodermatology Group guidelines for narrowband ultraviolet B phototherapy 2022. Br J Dermatol. 2022 Sep;187(3):295-308.[Full Text]

            • 85. Carbone M, Conrotto D, Carrozzo M, et al. Topical corticosteroids in association with miconazole and chlorhexidine in the long-term management of atrophic-erosive oral lichen planus: a placebo-controlled and comparative study between clobetasol and fluocinonide. Oral Dis. 1999 Jan;5(1):44-9.[Abstract]

            • 86. Lozada-Nur F, Miranda C, Maliksi R. Double-blind clinical trial of 0.05% clobetasol propionate (corrected from proprionate) ointment in orabase and 0.05% fluocinonide ointment in orabase in the treatment of patients with oral vesiculoerosive diseases. Oral Surg Oral Med Oral Pathol. 1994 Jun;77(6):598-604.[Abstract]

            • 87. Thongprasom K, Luengvisut P, Wongwatanakij A, et al. Clinical evaluation in treatment of oral lichen planus with topical fluocinolone acetonide: a 2-year follow-up. J Oral Pathol Med. 2003 Jul;32(6):315-22.[Abstract]

            • 88. Tyldesley WR, Harding SM. Betamethasone valerate aerosol in the treatment of oral lichen planus. Br J Dermatol. 1977 Jun;96(6):659-62.[Abstract]

            • 89. Voute AB, Schulten EA, Langendijk PN, et al. Fluocinonide in an adhesive base for treatment of oral lichen planus: a double-blind, placebo-controlled clinical study. Oral Surg Oral Med Oral Pathol. 1993 Feb;75(2):181-5.[Abstract]

            • 90. Ekelem C, Juhasz M, Khera P, et al. Utility of Naltrexone Treatment for Chronic Inflammatory Dermatologic Conditions: A Systematic Review. JAMA Dermatol. 2019 Feb 1;155(2):229-36.[Abstract][Full Text]

            • 91. Xiong C, Li Q, Lin M, et al. The efficacy of topical intralesional BCG-PSN injection in the treatment of erosive oral lichen planus: a randomized controlled trial. J Oral Pathol Med. 2009 Aug;38(7):551-8.[Abstract]

            • 92. Hanna R, Dalvi S, Tomov G, et al. Emerging potential of phototherapy in management of symptomatic oral lichen planus: a systematic review of randomised controlled clinical trials. J Biophotonics. 2023 Jul;16(7):e202300046.[Abstract]

            • 93. Hoseinpour Jajarm H, Asadi R, Bardideh E, et al. The effects of photodynamic and low-level laser therapy for treatment of oral lichen planus-a systematic review and meta-analysis. Photodiagnosis Photodyn Ther. 2018 Sep;23:254-60.[Abstract]

            • 94. Mostafa WZ. Lichen planus of the nail: treatment with antimalarials. J Am Acad Dermatol. 1989 Feb;20(2 pt 1):289-90.[Abstract]

            • 95. Irla N, Schneiter T, Haneke E, et al. Nail lichen planus: successful treatment with etanercept. Case Rep Dermatol. 2010 Oct 21;2(3):173-6.[Abstract][Full Text]

            • 96. Sigurgeirsson B, Lindelof B. Lichen planus and malignancy: an epidemiologic study of 2071 patients and a review of the literature. Arch Dermatol. 1991 Nov;127(11):1684-8.[Abstract]

            • 97. Cooper SM, Wojnarowska F. Influence of treatment of erosive lichen planus of the vulva on its prognosis. Arch Dermatol. 2006 Mar;142(3):289-94.[Abstract][Full Text]

            • 98. Gonzalez-Moles MA, Scully C, Gil-Montoya JA. Oral lichen planus: controversies surrounding malignant transformation. Oral Dis. 2008 Apr;14(3):229-43.[Abstract]

            • 99. Leis M, Singh A, Li C, et al. Risk of vulvar squamous cell carcinoma in lichen sclerosus and lichen planus: a systematic review. J Obstet Gynaecol Can. 2022 Feb;44(2):182-92.[Abstract]

            • 100. Offen E, Allison JR. What is the malignant transformation potential of oral lichen planus? Evid Based Dent. 2022 Mar;23(1):36-7.[Abstract]

            • 101. Iocca O, Sollecito TP, Alawi F, et al. Potentially malignant disorders of the oral cavity and oral dysplasia: a systematic review and meta-analysis of malignant transformation rate by subtype. Head Neck. 2020 Mar;42(3):539-55.[Abstract]

            • 102. Cheng H, Oakley A, Conaglen JV, et al. Quality of life and sexual distress in women with erosive vulvovaginal lichen planus. J Low Genit Tract Dis. 2017 Apr;21(2):145-9.[Abstract]

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