Highlights & Basics
- Retinal detachment (RD) is an acute or progressive condition in which the neuroretina separates from the retinal pigment epithelium, subretinal fluid accumulates, and retinal function is lost.
- Presents as primary rhegmatogenous RD, secondary to traction, or exudative in nature.
- In rhegmatogenous RD, retinal discontinuity promotes detachment.
- Diagnosis usually relies on indirect ophthalmoscopy or slit-lamp exam, with B-scan ultrasonography reserved for cases with media opacity.
- Left untreated, rhegmatogenous RD typically results in blindness.
Quick Reference
History & Exam
Key Factors
Other Factors
Diagnostics Tests
Treatment Options
Definition
Epidemiology
Etiology
Pathophysiology
Images
Citations
Kim SJ, Bailey ST, Kovach JL, et al. Posterior vitreous detachment, retinal breaks, and lattice degeneration preferred practice pattern®. Ophthalmology. 2025 Apr;132(4):P163-96.[Full Text]
American Academy of Ophthalmology. Referral of persons with possible eye diseases or injury - 2014. Apr 2014 [internet publication].[Full Text]
Hikichi T, Trempe CL. Relationship between floaters, light flashes, or both, and complications of posterior vitreous detachment. Am J Ophthalmol. 1994;117:593-8.[Abstract]
Znaor L, Medic A, Binder S, et al. Pars plana vitrectomy versus scleral buckling for repairing simple rhegmatogenous retinal detachments. Cochrane Database Syst Rev. 2019 Mar 8;(3):CD009562.[Abstract][Full Text]
Sena DF, Kilian R, Liu SH, et al. Pneumatic retinopexy versus scleral buckle for repairing simple rhegmatogenous retinal detachments. Cochrane Database Syst Rev. 2021 Nov 11;(11):CD008350.[Abstract][Full Text]
1. Robertson DM, Norton EW. Long-term follow-up of treated retinal breaks. Am J Ophthalmol. 1973;75:395-404.[Abstract]
2. Amer R, Nalcı H, Yalçındağ N. Exudative retinal detachment. Surv Ophthalmol. 2017 Nov-Dec;62(6):723-69.[Abstract]
3. Matsuo T, Eguchi K, Matsuo N. Unusual exudative retinal detachment 9 months after scleral buckling surgery. Ophthalmologica. 1990;201(2):79-82.[Abstract]
4. Aaberg TM, Pawlowski GJ. Exudative retinal detachments following scleral buckling with cryotherapy. Am J Ophthalmol. 1972 Aug;74(2):245-51.[Abstract]
5. Rowe JA, Erie JC, Baratz KH, et al. Retinal detachment in Olmsted County, Minnesota, 1976 through 1995. Ophthalmology. 1999;106:154-9.[Abstract]
6. Wilkes SR, Beard CM, Kurland LT, et al. The incidence of retinal detachment in Rochester, Minnesota, 1970-1978. Am J Ophthalmol. 1982;94:670-3.[Abstract]
7. Li JQ, Welchowski T, Schmid M, et al. Incidence of rhegmatogenous retinal detachment in Europe - a systematic review and meta-analysis. Ophthalmologica. 2019;242(2):81-6.[Abstract]
8. Nielsen BR, Alberti M, Bjerrum SS, et al. The incidence of rhegmatogenous retinal detachment is increasing. Acta Ophthalmol. 2020 Sep;98(6):603-6.[Abstract][Full Text]
9. Achour H, Thomseth VM, Kvaløy JT, et al. Substantial increase in the incidence of rhegmatogenous retinal detachment in Western Norway over 20 years. Acta Ophthalmol. 2022 Nov;100(7):763-8.[Abstract]
10. Chou SC, Yang CH, Lee CH, et al. Characteristics of primary rhegmatogenous retinal detachment in Taiwan. Eye. 2007;21:1056-61.[Abstract]
11. Van de Put MAJ, Hooymans JMM, Los LI, et al. The incidence of rhegmatogenous retinal detachment in The Netherlands. Ophthalmology. 2013 Mar;120(3):616-22.[Abstract]
12. Kuhn F, Aylward B. Rhegmatogenous retinal detachment: a reappraisal of its pathophysiology and treatment. Ophthalmic Res. 2014;51(1):15-31.[Abstract]
13. Byer NE. Subclinical retinal detachment resulting from asymptomatic retinal breaks: prognosis for progression and regression. Ophthalmology. 2001;108:1499-1503.[Abstract]
14. Feder RS, Olsen TW, Prum BE Jr, et al. Comprehensive adult medical eye evaluation Preferred Practice Pattern® guidelines. Ophthalmology. 2016 Jan;123(1):P209-36.[Abstract][Full Text]
15. Kawaguchi T, Spencer DB, Mochizuki M. Therapy for acute retinal necrosis. Semin Ophthalmol. 2008;23:285-90.[Abstract]
16. Madi HA, Keller J. Increasing frequency of hospital admissions for retinal detachment and vitreo-retinal surgery in England 2000-2018. Eye (Lond). 2022 Aug;36(8):1610-4.[Abstract][Full Text]
17. Kim SJ, Bailey ST, Kovach JL, et al. Posterior vitreous detachment, retinal breaks, and lattice degeneration preferred practice pattern®. Ophthalmology. 2025 Apr;132(4):P163-96.[Full Text]
18. Morse PH, Scheie HG. Rhegmatogenous retinal detachment in patients aged 40 years or less. Trans Ophthalmol Soc U K. 1975;95:128-33.[Abstract]
19. America Academy of Ophthalmology. Pediatric retinal detachments. Sep 2021 [internet publication].[Full Text]
20. Kassem R, Greenwald Y, Achiron A, et al. Peak occurrence of retinal detachment following cataract surgery: a systematic review and pooled analysis with internal validation. J Ophthalmol. 2018;2018:9206418.[Abstract][Full Text]
21. Hyams SW, Bialik M, Neumann E. Myopia-aphakia. I: prevalence of retinal detachment. Br J Ophthalmol. 1975;59:480-2.[Abstract][Full Text]
22. Rickman-Barger L, Florine CW, Larson RS, et al. Retinal detachment after neodymium:YAG laser posterior capsulotomy. Am J Ophthalmol. 1989;107:531-6.[Abstract]
23. Ahmadieh H, Soheilian M, Sajjadi H, et al. Vitrectomy in ocular trauma: factors influencing final visual outcome. Retina. 1993;13:107-13.[Abstract]
24. Duquesne N, Bonnet M, Adeleine P. Preoperative vitreous hemorrhage associated with rhegmatogenous retinal detachment: a risk factor for postoperative proliferative vitreoretinopathy? Graefes Arch Clin Exp Ophthalmol. 1996;234:677-82.[Abstract]
25. Folk JC, Arrindell EL, Klugman MR. The fellow eye of patients with phakic lattice retinal detachment. Ophthalmology. 1989;96:72-9.[Abstract]
26. Mastropasqua L, Carpineto P, Ciancaglini M, et al. Treatment of retinal tears and lattice degenerations in fellow eyes in high risk patients suffering retinal detachment: a prospective study. Br J Ophthalmol. 1999 Sep;83(9):1046-9.[Abstract][Full Text]
27. Hutchinson AK, Morse CL, Hercinovic A, et al. Pediatric eye evaluations preferred practice pattern. Ophthalmology. 2023 Mar;130(3):P222-70.[Abstract][Full Text]
28. Lau CH, Missotten T, Salzmann J, et al. Acute retinal necrosis features, management, and outcomes. Ophthalmology. 2007;114:756-62.[Abstract]
29. Stewart JM, Cubillan LD, Cunningham ET Jr. Prevalence, clinical features, and causes of vision loss among patients with ocular toxocariasis. Retina. 2005;25:1005-13.[Abstract]
30. Spencer LM, Foos RY, Straatsma BR. Enclosed bays of the ora serrata: relationship to retina tears. Arch Ophthalmol. 1970;83:421-5.[Abstract]
31. Schepens CL. Subclinical retinal detachments. AMA Arch Ophthalmol. 1952;47:593-606.[Abstract]
32. Curtin BJ. The myopias: basic science and clinical management. New York, NY: Harper & Row; 1985:339.
33. Lewis H. Peripheral retinal degenerations and the risk of retinal detachment. Am J Ophthalmol. 2003;136:155-60.[Abstract]
34. Shea M, Schepens CL, Von Pirquet SR. Retinoschisis. I: senile type: a clinical report of one hundred seven cases. Arch Ophthalmol. 1960;63:1-69.[Abstract]
35. Byer NE. Relationship of cystic retinal tufts to retinal detachment. Dev Ophthalmol. 1981;2:36-42.[Abstract]
36. Etminan M, Sodhi M, Mikelberg FS, et al. Risk of ocular adverse events associated with use of phosphodiesterase 5 inhibitors in men in the US. JAMA Ophthalmol. 2022 May 1;140(5):480-4.[Abstract][Full Text]
37. American Academy of Ophthalmology. Referral of persons with possible eye diseases or injury - 2014. Apr 2014 [internet publication].[Full Text]
38. National Institute for health and Care Excellence. Retinal detachment: scenario: management of suspected retinal detachment. Aug 2019 [internet publication].[Full Text]
39. Hikichi T, Trempe CL. Relationship between floaters, light flashes, or both, and complications of posterior vitreous detachment. Am J Ophthalmol. 1994;117:593-8.[Abstract]
40. Wallsh JO, Langevin ST, Kumar A, et al. Fellow-eye retinal detachment risk as stratified by hyaloid status on OCT. Ophthalmology. 2023 Jun;130(6):624-30.[Abstract]
41. Uchino E, Uemura A, Ohba N. Initial stages of posterior vitreous detachment in healthy eyes of older persons evaluated by optical coherence tomography. Arch Ophthalmol. 2001 Oct;119(10):1475-9.[Abstract][Full Text]
42. Wong D, Restori M. Ultrasonic Doppler studies of the vitreous. Eye. 1988;2:87-91.[Abstract]
43. Rabinowitz R, Yagev R, Shoham A, et al. Comparison between clinical and ultrasound findings in patients with vitreous hemorrhage. Eye. 2004;18:253-256.[Abstract][Full Text]
44. Verbraeken H, Van Egmond. Non-diabetic and non-oculotraumatic vitreous haemorrhage treated by pars plana vitrectomy. Bull Soc Belge Ophtalmol. 1999;272:83-9.[Abstract]
45. Bailey ST, Vemulakonda GA, Kim SJ, et al. Idiopathic epiretinal membrane and vitreomacular traction preferred practice pattern®. Ophthalmology. 2025 Apr;132(4):P197-233.[Full Text]
46. Regillo CD, Custis PH. Surgical management of retinoschisis. Curr Opin Ophthalmol. 1997;8:80-6.[Abstract]
47. Azad RV, Tewari HK, Khosla PK. Natural history of retinal detachment on the basis of the study of the fellow eye. Indian J Ophthalmol. 1983;31:170-3.[Abstract][Full Text]
48. American Academy of Ophthalmology. Retina summary benchmarks - 2024. Dec 2024 [internet publication].[Full Text]
49. American Academy of Ophthalmology. Frequency of ocular examinations - 2015. Mar 2015 [internet publication].[Full Text]
50. Rosengren B. Principles of detachment surgery. Acta Ophthalmol (Copenh). 1966;Suppl 84:111[Abstract]
51. Sothivannan A, Eshtiaghi A, Dhoot AS, et al. Impact of the time to surgery on visual outcomes for rhegmatogenous retinal detachment repair: a meta-analysis. Am J Ophthalmol. 2022 Dec;244:19-29.[Abstract]
52. Znaor L, Medic A, Binder S, et al. Pars plana vitrectomy versus scleral buckling for repairing simple rhegmatogenous retinal detachments. Cochrane Database Syst Rev. 2019 Mar 8;(3):CD009562.[Abstract][Full Text]
53. Hillier RJ, Felfeli T, Berger AR, et al. The pneumatic retinopexy versus vitrectomy for the management of primary rhegmatogenous retinal detachment outcomes randomized trial (PIVOT). Ophthalmology. 2019 Apr;126(4):531-9.[Abstract][Full Text]
54. Zaidi AA, Alvarado R, Irvine A. Pneumatic retinopexy: success rate and complications. Br J Ophthalmol. 2006 Apr;90(4):427-8.[Abstract][Full Text]
55. Davis MJ, Mudvari SS, Shott S, et al. Clinical characteristics affecting the outcome of pneumatic retinopexy. Arch Ophthalmol. 2011 Feb;129(2):163-6.[Abstract][Full Text]
56. Kulkarni KM, Roth DB, Prenner JL. Current visual and anatomic outcomes of pneumatic retinopexy. Retina. 2007 Oct;27(8):1065-70.[Abstract]
57. Chan CK, Lin SG, Nuthi AS, et al. Pneumatic retinopexy for the repair of retinal detachments: a comprehensive review (1986-2007). Surv Ophthalmol. 2008;53:443-78.[Abstract]
58. Sena DF, Kilian R, Liu SH, et al. Pneumatic retinopexy versus scleral buckle for repairing simple rhegmatogenous retinal detachments. Cochrane Database Syst Rev. 2021 Nov 11;(11):CD008350.[Abstract][Full Text]
59. Wang A, Snead MP. Scleral buckling-a brief historical overview and current indications. Graefes Arch Clin Exp Ophthalmol. 2020 Mar;258(3):467-78.[Abstract][Full Text]
60. Stewart S, Chan W. Pneumatic retinopexy: patient selection and specific factors. Clin Ophthalmol. 2018;12:493-502.[Abstract][Full Text]
61. Yamakiri K, Sakamoto T, Noda Y, et al. Reduced incidence of intraoperative complications in a multicenter controlled clinical trial of triamcinolone in vitrectomy. Ophthalmology. 2007;114:289-96.[Abstract]
62. Sundaram V, Barsam A, Virgili G. Intravitreal low molecular weight heparin and 5-Fluorouracil for the prevention of proliferative vitreoretinopathy following retinal reattachment surgery. Cochrane Database Syst Rev. 2013 Jan 31;(1):CD006421.[Abstract][Full Text]
63. Schaub F, Hoerster R, Schiller P, et al. Prophylactic intravitreal 5-fluorouracil and heparin to prevent proliferative vitreoretinopathy in high-risk patients with retinal detachment: study protocol for a randomized controlled trial. Trials. 2018 Jul 16;19(1):384.[Abstract][Full Text]
64. US National Library of Medicine. Prophylactic intravitreal 5-fluorouracil and heparin to prevent PVR in high-risk patients with retinal detachment. Apr 2022 [internet publication].[Full Text]
65. Richardson EC, Verma S, Green WT, et al. Primary vitrectomy for rhegmatogenous retinal detachment: an analysis of failure. Eur J Ophthalmol. 2000;10:160-6.[Abstract]
66. Malbran E, Dodds RA, Hulsbus R, et al. Retinal break type and proliferative vitreoretinopathy in nontraumatic retinal detachment. Graefes Arch Clin Exp Ophthalmol. 1990;228:423-5.[Abstract]
67. Ryan SJ. The pathophysiology of proliferative vitreoretinopathy in its management. Am J Ophthalmol. 1985;100:188-93.[Abstract]
68. Laqua H. Current concepts in the management of complex retinal detachments. Trans Ophthalmol Soc U K. 1983;103:133-8.[Abstract]
69. Yeo JH, Glaser BM, Michels RG. Silicone oil in the treatment of complicated retinal detachments. Ophthalmology. 1987;94:1109-13.[Abstract]
70. Michels RG. Surgery of retinal detachment with proliferative vitreoretinopathy. Retina. 1984;4:63-83.[Abstract]
71. Kwok AKh, Lai TY, Yuen KS. Epiretinal membrane surgery with or without internal limiting membrane peeling. Clin Experiment Ophthalmol. 2005;33:379-85.[Abstract]
72. Emami S, Kitayama K, Coleman AL. Adjunctive steroid therapy versus antibiotics alone for acute endophthalmitis after intraocular procedure. Cochrane Database Syst Rev. 2022 Jun 6;(6):CD012131.[Abstract][Full Text]
73. Xu ZY, Azuara-Blanco A, Kadonosono K, et al. New classification for the reporting of complications in retinal detachment surgical trials. JAMA Ophthalmol. 2021 Aug 1;139(8):857-64.[Abstract][Full Text]
74. Perez RN, Phelps CD, Burton TC. Angel-closure glaucoma following scleral buckling operations. Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol. 1976;81:247-52.[Abstract]
75. Michels RG. Vitrectomy methods in penetrating ocular trauma. Ophthalmology. 1980;87:629-45.[Abstract]
76. Hilton GF, Tornambe PE. Pneumatic retinopexy: an analysis of intraoperative and postoperative complications. The Retinal Detachment Study Group. Retina. 1991;11:285-94.[Abstract]
77. Yeung L, Yang KJ, Chen TL, et al. Association between severity of vitreous haemorrhage and visual outcome in primary rhegmatogenous retinal detachment. Ophthalmology. 2008;86:165-9.[Abstract]
78. Jackson ML, Virgili G, Shepherd JD, et al. Vision rehabilitation preferred practice pattern®. Ophthalmology. 2023 Mar;130(3):P271-335.[Full Text]
79. American Academy of Ophthalmology. Recommendations on assistive technology for patients with low vision - 2025. Mar 2025 [internet publication].[Full Text]
80. Morris R, Kuhn F, Witherspoon CD, et al. Prophylactic scleral buckle for prevention of retinal detachment following vitrectomy for macular hole. Br J Ophthalmol. 2000;84:673.[Abstract][Full Text]
81. Avitabile T, Longo A, Lentini G, et al. Retinal detachment after silicone oil removal is prevented by 360 degrees laser treatment. Br J Ophthalmol. 2008;92:1479-82.[Abstract]
82. Schwartz SG, Flynn HW Jr, Wang X, et al. Tamponade in surgery for retinal detachment associated with proliferative vitreoretinopathy. Cochrane Database Syst Rev. 2020 May 13;5:CD006126.[Abstract][Full Text]