Highlights & Basics
- Retinal detachment (RD) is an acute or progressive condition in which the neuroretina separates from the retinal pigment epithelium, subretinal fluid accumulates, and retinal function is lost.
- Presents as primary rhegmatogenous RD, secondary to traction, or exudative in nature.
- In rhegmatogenous RD, retinal discontinuity promotes detachment.
- Diagnosis usually relies on indirect ophthalmoscopy or slit-lamp exam, with B-scan ultrasonography reserved for cases with media opacity.
- Left untreated, rhegmatogenous RD typically results in blindness.
Quick Reference
History & Exam
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Definition
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Citations
American Academy of Ophthalmology. Posterior vitreous detachment, retinal breaks, and lattice degeneration preferred practice pattern®. Sep 2019 [internet publication].[Abstract][Full Text]
American Academy of Ophthalmology. Referral of persons with possible eye diseases or injury - 2014. Apr 2014 [internet publication].[Full Text]
Hikichi T, Trempe CL. Relationship between floaters, light flashes, or both, and complications of posterior vitreous detachment. Am J Ophthalmol. 1994;117:593-8.[Abstract]
Znaor L, Medic A, Binder S, et al. Pars plana vitrectomy versus scleral buckling for repairing simple rhegmatogenous retinal detachments. Cochrane Database Syst Rev. 2019 Mar 8;(3):CD009562.[Abstract][Full Text]
Sena DF, Kilian R, Liu SH, et al. Pneumatic retinopexy versus scleral buckle for repairing simple rhegmatogenous retinal detachments. Cochrane Database Syst Rev. 2021 Nov 11;(11):CD008350.[Abstract][Full Text]
1. Robertson DM, Norton EW. Long-term follow-up of treated retinal breaks. Am J Ophthalmol. 1973;75:395-404.[Abstract]
2. Amer R, Nalcı H, Yalçındağ N. Exudative retinal detachment. Surv Ophthalmol. 2017 Nov-Dec;62(6):723-69.[Abstract]
3. Matsuo T, Eguchi K, Matsuo N. Unusual exudative retinal detachment 9 months after scleral buckling surgery. Ophthalmologica. 1990;201(2):79-82.[Abstract]
4. Aaberg TM, Pawlowski GJ. Exudative retinal detachments following scleral buckling with cryotherapy. Am J Ophthalmol. 1972 Aug;74(2):245-51.[Abstract]
5. Rowe JA, Erie JC, Baratz KH, et al. Retinal detachment in Olmsted County, Minnesota, 1976 through 1995. Ophthalmology. 1999;106:154-9.[Abstract]
6. Wilkes SR, Beard CM, Kurland LT, et al. The incidence of retinal detachment in Rochester, Minnesota, 1970-1978. Am J Ophthalmol. 1982;94:670-3.[Abstract]
7. Li JQ, Welchowski T, Schmid M, et al. Incidence of rhegmatogenous retinal detachment in Europe - a systematic review and meta-analysis. Ophthalmologica. 2019;242(2):81-6.[Abstract]
8. Nielsen BR, Alberti M, Bjerrum SS, et al. The incidence of rhegmatogenous retinal detachment is increasing. Acta Ophthalmol. 2020 Sep;98(6):603-6.[Abstract][Full Text]
9. Achour H, Thomseth VM, Kvaløy JT, et al. Substantial increase in the incidence of rhegmatogenous retinal detachment in Western Norway over 20 years. Acta Ophthalmol. 2022 Nov;100(7):763-8.[Abstract]
10. Chou SC, Yang CH, Lee CH, et al. Characteristics of primary rhegmatogenous retinal detachment in Taiwan. Eye. 2007;21:1056-61.[Abstract]
11. Van de Put MAJ, Hooymans JMM, Los LI, et al. The incidence of rhegmatogenous retinal detachment in The Netherlands. Ophthalmology. 2013 Mar;120(3):616-22.[Abstract]
12. Kuhn F, Aylward B. Rhegmatogenous retinal detachment: a reappraisal of its pathophysiology and treatment. Ophthalmic Res. 2014;51(1):15-31.[Abstract]
13. Byer NE. Subclinical retinal detachment resulting from asymptomatic retinal breaks: prognosis for progression and regression. Ophthalmology. 2001;108:1499-1503.[Abstract]
14. Feder RS, Olsen TW, Prum BE Jr, et al. Comprehensive adult medical eye evaluation Preferred Practice Pattern® guidelines. Ophthalmology. 2016 Jan;123(1):P209-36.[Abstract][Full Text]
15. Kawaguchi T, Spencer DB, Mochizuki M. Therapy for acute retinal necrosis. Semin Ophthalmol. 2008;23:285-90.[Abstract]
16. Madi HA, Keller J. Increasing frequency of hospital admissions for retinal detachment and vitreo-retinal surgery in England 2000-2018. Eye (Lond). 2022 Aug;36(8):1610-4.[Abstract][Full Text]
17. American Academy of Ophthalmology. Posterior vitreous detachment, retinal breaks, and lattice degeneration preferred practice pattern®. Sep 2019 [internet publication].[Abstract][Full Text]
18. Morse PH, Scheie HG. Rhegmatogenous retinal detachment in patients aged 40 years or less. Trans Ophthalmol Soc U K. 1975;95:128-33.[Abstract]
19. America Academy of Ophthalmology. Pediatric retinal detachments. Sep 2021 [internet publication].[Full Text]
20. Kassem R, Greenwald Y, Achiron A, et al. Peak occurrence of retinal detachment following cataract surgery: a systematic review and pooled analysis with internal validation. J Ophthalmol. 2018;2018:9206418.[Abstract][Full Text]
21. Hyams SW, Bialik M, Neumann E. Myopia-aphakia. I: prevalence of retinal detachment. Br J Ophthalmol. 1975;59:480-2.[Abstract][Full Text]
22. Rickman-Barger L, Florine CW, Larson RS, et al. Retinal detachment after neodymium:YAG laser posterior capsulotomy. Am J Ophthalmol. 1989;107:531-6.[Abstract]
23. Ahmadieh H, Soheilian M, Sajjadi H, et al. Vitrectomy in ocular trauma: factors influencing final visual outcome. Retina. 1993;13:107-13.[Abstract]
24. Duquesne N, Bonnet M, Adeleine P. Preoperative vitreous hemorrhage associated with rhegmatogenous retinal detachment: a risk factor for postoperative proliferative vitreoretinopathy? Graefes Arch Clin Exp Ophthalmol. 1996;234:677-82.[Abstract]
25. Folk JC, Arrindell EL, Klugman MR. The fellow eye of patients with phakic lattice retinal detachment. Ophthalmology. 1989;96:72-9.[Abstract]
26. Mastropasqua L, Carpineto P, Ciancaglini M, et al. Treatment of retinal tears and lattice degenerations in fellow eyes in high risk patients suffering retinal detachment: a prospective study. Br J Ophthalmol. 1999 Sep;83(9):1046-9.[Abstract][Full Text]
27. Hutchinson AK, Morse CL, Hercinovic A, et al. Pediatric eye evaluations preferred practice pattern. Ophthalmology. 2023 Mar;130(3):P222-70.[Abstract][Full Text]
28. Lau CH, Missotten T, Salzmann J, et al. Acute retinal necrosis features, management, and outcomes. Ophthalmology. 2007;114:756-62.[Abstract]
29. Stewart JM, Cubillan LD, Cunningham ET Jr. Prevalence, clinical features, and causes of vision loss among patients with ocular toxocariasis. Retina. 2005;25:1005-13.[Abstract]
30. Spencer LM, Foos RY, Straatsma BR. Enclosed bays of the ora serrata: relationship to retina tears. Arch Ophthalmol. 1970;83:421-5.[Abstract]
31. Schepens CL. Subclinical retinal detachments. AMA Arch Ophthalmol. 1952;47:593-606.[Abstract]
32. Curtin BJ. The myopias: basic science and clinical management. New York, NY: Harper & Row; 1985:339.
33. Lewis H. Peripheral retinal degenerations and the risk of retinal detachment. Am J Ophthalmol. 2003;136:155-60.[Abstract]
34. Shea M, Schepens CL, Von Pirquet SR. Retinoschisis. I: senile type: a clinical report of one hundred seven cases. Arch Ophthalmol. 1960;63:1-69.[Abstract]
35. Byer NE. Relationship of cystic retinal tufts to retinal detachment. Dev Ophthalmol. 1981;2:36-42.[Abstract]
36. Etminan M, Sodhi M, Mikelberg FS, et al. Risk of ocular adverse events associated with use of phosphodiesterase 5 inhibitors in men in the US. JAMA Ophthalmol. 2022 May 1;140(5):480-4.[Abstract][Full Text]
37. American Academy of Ophthalmology. Referral of persons with possible eye diseases or injury - 2014. Apr 2014 [internet publication].[Full Text]
38. National Institute for health and Care Excellence. Retinal detachment: scenario: management of suspected retinal detachment. Aug 2019 [internet publication].[Full Text]
39. Hikichi T, Trempe CL. Relationship between floaters, light flashes, or both, and complications of posterior vitreous detachment. Am J Ophthalmol. 1994;117:593-8.[Abstract]
40. Uchino E, Uemura A, Ohba N. Initial stages of posterior vitreous detachment in healthy eyes of older persons evaluated by optical coherence tomography. Arch Ophthalmol. 2001 Oct;119(10):1475-9.[Abstract][Full Text]
41. Wong D, Restori M. Ultrasonic Doppler studies of the vitreous. Eye. 1988;2:87-91.[Abstract]
42. Rabinowitz R, Yagev R, Shoham A, et al. Comparison between clinical and ultrasound findings in patients with vitreous hemorrhage. Eye. 2004;18:253-256.[Abstract][Full Text]
43. Verbraeken H, Van Egmond. Non-diabetic and non-oculotraumatic vitreous haemorrhage treated by pars plana vitrectomy. Bull Soc Belge Ophtalmol. 1999;272:83-9.[Abstract]
44. Regillo CD, Custis PH. Surgical management of retinoschisis. Curr Opin Ophthalmol. 1997;8:80-6.[Abstract]
45. Azad RV, Tewari HK, Khosla PK. Natural history of retinal detachment on the basis of the study of the fellow eye. Indian J Ophthalmol. 1983;31:170-3.[Abstract][Full Text]
46. American Academy of Ophthalmology. Retina summary benchmarks - 2023. Dec 2023 [internet publication].[Full Text]
47. American Academy of Ophthalmology. Frequency of ocular examinations - 2015. Mar 2015 [internet publication].[Full Text]
48. Rosengren B. Principles of detachment surgery. Acta Ophthalmol (Copenh). 1966;Suppl 84:111[Abstract]
49. Sothivannan A, Eshtiaghi A, Dhoot AS, et al. Impact of the time to surgery on visual outcomes for rhegmatogenous retinal detachment repair: a meta-analysis. Am J Ophthalmol. 2022 Dec;244:19-29.[Abstract]
50. Znaor L, Medic A, Binder S, et al. Pars plana vitrectomy versus scleral buckling for repairing simple rhegmatogenous retinal detachments. Cochrane Database Syst Rev. 2019 Mar 8;(3):CD009562.[Abstract][Full Text]
51. Hillier RJ, Felfeli T, Berger AR, et al. The pneumatic retinopexy versus vitrectomy for the management of primary rhegmatogenous retinal detachment outcomes randomized trial (PIVOT). Ophthalmology. 2019 Apr;126(4):531-9.[Abstract][Full Text]
52. Zaidi AA, Alvarado R, Irvine A. Pneumatic retinopexy: success rate and complications. Br J Ophthalmol. 2006 Apr;90(4):427-8.[Abstract][Full Text]
53. Davis MJ, Mudvari SS, Shott S, et al. Clinical characteristics affecting the outcome of pneumatic retinopexy. Arch Ophthalmol. 2011 Feb;129(2):163-6.[Abstract][Full Text]
54. Kulkarni KM, Roth DB, Prenner JL. Current visual and anatomic outcomes of pneumatic retinopexy. Retina. 2007 Oct;27(8):1065-70.[Abstract]
55. Chan CK, Lin SG, Nuthi AS, et al. Pneumatic retinopexy for the repair of retinal detachments: a comprehensive review (1986-2007). Surv Ophthalmol. 2008;53:443-78.[Abstract]
56. Sena DF, Kilian R, Liu SH, et al. Pneumatic retinopexy versus scleral buckle for repairing simple rhegmatogenous retinal detachments. Cochrane Database Syst Rev. 2021 Nov 11;(11):CD008350.[Abstract][Full Text]
57. Wang A, Snead MP. Scleral buckling-a brief historical overview and current indications. Graefes Arch Clin Exp Ophthalmol. 2020 Mar;258(3):467-78.[Abstract][Full Text]
58. Stewart S, Chan W. Pneumatic retinopexy: patient selection and specific factors. Clin Ophthalmol. 2018;12:493-502.[Abstract][Full Text]
59. Yamakiri K, Sakamoto T, Noda Y, et al. Reduced incidence of intraoperative complications in a multicenter controlled clinical trial of triamcinolone in vitrectomy. Ophthalmology. 2007;114:289-96.[Abstract]
60. Sundaram V, Barsam A, Virgili G. Intravitreal low molecular weight heparin and 5-Fluorouracil for the prevention of proliferative vitreoretinopathy following retinal reattachment surgery. Cochrane Database Syst Rev. 2013 Jan 31;(1):CD006421.[Abstract][Full Text]
61. Schaub F, Hoerster R, Schiller P, et al. Prophylactic intravitreal 5-fluorouracil and heparin to prevent proliferative vitreoretinopathy in high-risk patients with retinal detachment: study protocol for a randomized controlled trial. Trials. 2018 Jul 16;19(1):384.[Abstract][Full Text]
62. US National Library of Medicine. Prophylactic intravitreal 5-fluorouracil and heparin to prevent PVR in high-risk patients with retinal detachment. Apr 2022 [internet publication].[Full Text]
63. Richardson EC, Verma S, Green WT, et al. Primary vitrectomy for rhegmatogenous retinal detachment: an analysis of failure. Eur J Ophthalmol. 2000;10:160-6.[Abstract]
64. Malbran E, Dodds RA, Hulsbus R, et al. Retinal break type and proliferative vitreoretinopathy in nontraumatic retinal detachment. Graefes Arch Clin Exp Ophthalmol. 1990;228:423-5.[Abstract]
65. Ryan SJ. The pathophysiology of proliferative vitreoretinopathy in its management. Am J Ophthalmol. 1985;100:188-93.[Abstract]
66. Laqua H. Current concepts in the management of complex retinal detachments. Trans Ophthalmol Soc U K. 1983;103:133-8.[Abstract]
67. Yeo JH, Glaser BM, Michels RG. Silicone oil in the treatment of complicated retinal detachments. Ophthalmology. 1987;94:1109-13.[Abstract]
68. Michels RG. Surgery of retinal detachment with proliferative vitreoretinopathy. Retina. 1984;4:63-83.[Abstract]
69. Kwok AKh, Lai TY, Yuen KS. Epiretinal membrane surgery with or without internal limiting membrane peeling. Clin Experiment Ophthalmol. 2005;33:379-85.[Abstract]
70. Emami S, Kitayama K, Coleman AL. Adjunctive steroid therapy versus antibiotics alone for acute endophthalmitis after intraocular procedure. Cochrane Database Syst Rev. 2022 Jun 6;(6):CD012131.[Abstract][Full Text]
71. Xu ZY, Azuara-Blanco A, Kadonosono K, et al. New classification for the reporting of complications in retinal detachment surgical trials. JAMA Ophthalmol. 2021 Aug 1;139(8):857-64.[Abstract][Full Text]
72. Perez RN, Phelps CD, Burton TC. Angel-closure glaucoma following scleral buckling operations. Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol. 1976;81:247-52.[Abstract]
73. Michels RG. Vitrectomy methods in penetrating ocular trauma. Ophthalmology. 1980;87:629-45.[Abstract]
74. Hilton GF, Tornambe PE. Pneumatic retinopexy: an analysis of intraoperative and postoperative complications. The Retinal Detachment Study Group. Retina. 1991;11:285-94.[Abstract]
75. Yeung L, Yang KJ, Chen TL, et al. Association between severity of vitreous haemorrhage and visual outcome in primary rhegmatogenous retinal detachment. Ophthalmology. 2008;86:165-9.[Abstract]
76. Morris R, Kuhn F, Witherspoon CD, et al. Prophylactic scleral buckle for prevention of retinal detachment following vitrectomy for macular hole. Br J Ophthalmol. 2000;84:673.[Abstract][Full Text]
77. Avitabile T, Longo A, Lentini G, et al. Retinal detachment after silicone oil removal is prevented by 360 degrees laser treatment. Br J Ophthalmol. 2008;92:1479-82.[Abstract]
78. Schwartz SG, Flynn HW Jr, Wang X, et al. Tamponade in surgery for retinal detachment associated with proliferative vitreoretinopathy. Cochrane Database Syst Rev. 2020 May 13;5:CD006126.[Abstract][Full Text]
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