Highlights & Basics
- An ovarian cyst is a fluid-filled sac in the ovarian tissue. The cyst may be unilocular or multilocular. The causes may be physiologic, infectious, benign neoplastic, malignant neoplastic, or metastatic.
- The most important step in management is assessing the risk of malignancy.
- Oral contraceptives do not hasten or influence regression of benign ovarian cysts.
- Asymptomatic postmenopausal women with simple unilocular ovarian cysts <10 cm in diameter and cancer antigen (CA)-125 <35 U/mL can be managed conservatively with serial ultrasonography.
- Ultrasonography can provide a morphology index score that is useful in determining likelihood of malignancy.
Quick Reference
History & Exam
Key Factors
Other Factors
Diagnostics Tests
Treatment Options
Definition
Epidemiology
Etiology
Pathophysiology
Citations
American College of Obstetricians and Gynecologists. American College of Obstetricians and Gynecologists' Committee on Practice Bulletins--Gynecology. Practice bulletin no. 174: evaluation and management of adnexal masses. Obstet Gynecol. 2016 Nov;128(5):e210-6.[Abstract]
DePriest PD, Shenson D, Fried A, et al. A morphology index based on sonographic findings in ovarian cancer. Gynecol Oncol. 1993 Oct;51(1):7-11.[Abstract]
Committee on Gynecologic Practice, Society of Gynecologic Oncology. Committee opinion no. 716: the role of the obstetrician-gynecologist in the early detection of epithelial ovarian cancer in women at average risk. Obstet Gynecol. 2017 Sep;130(3):e146-9.[Abstract]
US Preventive Services Task Force; Grossman DC, Curry SJ, Owens DK, et al. Screening for ovarian cancer: US Preventive Services Task Force recommendation statement. JAMA. 2018 Feb 13;319(6):588-94.[Abstract]
Levine D, Patel MD, Suh-Burgmann EJ, et al. Simple adnexal cysts: SRU consensus conference update on follow-up and reporting. Radiology. 2019 Nov;293(2):359-71.[Abstract][Full Text]
Grimes DA, Jones LB, Lopez LM, et al. Oral contraceptives for functional ovarian cysts. Cochrane Database Syst Rev. 2014 Apr 29;(4):CD006134.[Abstract][Full Text]
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28. Goff BA, Mandel LS, Drescher CW, et al. Development of an ovarian cancer symptom index: possibilities for earlier detection. Cancer. 2007 Jan 15;109(2):221-7.[Abstract][Full Text]
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33. Alcazar JL, Castillo G, Jurado M, et al. Is expectant management of sonographically benign adnexal cysts an option in selected asymptomatic premenopausal women? Hum Reprod. 2005 Nov;20(11):3231-4.[Abstract][Full Text]
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59. Wolfman W, Thurston J, Yeung G, et al. Guideline no. 404: initial investigation and management of benign ovarian masses. J Obstet Gynaecol Can. 2020 Aug;42(8):1040-1050.e1.[Abstract]
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64. Gocmen A, Karac M, Sari A. Conservative laparoscopic approach to adnexal torsion. Arch Gynecol Obstet. 2008 Jun;277(6):535-8.[Abstract]
65. Castillo G, Alcazar JL, Jurado M. Natural history of sonographically detected simple unilocular adnexal cysts in asymptomatic postmenopausal women. Gynecol Oncol. 2004 Mar;92(3):965-9.[Abstract]
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67. Parker WH, Broder MS, Liu Z, et al. Ovarian conservation at the time of hysterectomy for benign disease. Clin Obstet Gynecol. 2007 Jun;50(2):354-61.[Abstract]
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