Summary
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Chest x-ray showing bilateral hilar adenopathy in a patient with sarcoidosis
Chest x-ray showing multiple miliary lung metastases (arrows). The primary tumor was a thyroid carcinoma
Chest x-ray showing left hilar carcinoma (arrow)
Chest x-ray showing a cavitating right hilar carcinoma (arrow)
Chest x-ray in a patient with bronchogenic carcinoma showing a left-sided pleural effusion
Chest x-ray showing pulmonary tuberculosis with cavitation
Chest x-ray showing multiple discrete nodules throughout both lungs (one of which is circled) in a patient with miliary tuberculosis
Chest x-ray with lack of normal tapering producing a tram line in a patient with bronchiectasis
Chest x-ray with dilated and thickened airways in a patient with bronchiectasis
Chest x-ray showing increased opacification of the right perihilar region and superior segment of the right lower and upper lobes consistent with worsening aspiration pneumonia
Chest x-ray showing early ill-defined opacities of the right upper lobe above the minor fissure consistent with early changes of aspiration pneumonia
Portable chest x-ray with bibasilar opacities, worse on the right than the left, in a patient with hospital-acquired pneumonia
A. Portable upright chest x-ray before aspiration; B. Chest x-ray 1 hour after aspiration, showing bilateral diffuse alveolar infiltrates, worse at the bases on the right side
Chest CT with presence of signet ring on left in a patient with bronchiectasis
Chest CT with dilated and thickened airways and peripheral tree-in-bud pattern in a patient with bronchiectasis
CT of the chest with intravenous contrast material showing complete left lower lobe collapse with a radiopaque object within the left lower main bronchus surrounded by a halo of air
Chest CT showing idiopathic pulmonary fibrosis
Chest CT of a patient with amiodarone pulmonary toxicity, showing asymmetric opacities with a peripheral distribution
Bronchoscopy image showing a loquat seed completely occluding the bronchus intermedius
Flow-volume loop (spirogram) in obstructive lung disease, such as asthma or COPD: peak expiratory flow may be normal, but a concave shape is seen following the point of maximal flow due to the low flow rate in relation to lung volume
Flow-volume loop (spirogram) in restrictive lung disease (e.g., interstitial pulmonary fibrosis): peak expiratory flow may be normal or low. The shape of the curve is generally normal, but the loop is narrowed and the forced vital capacity is low because of the reduced lung volume.
Citations
Morice AH, Millqvist E, Bieksiene K, et al. ERS guidelines on the diagnosis and treatment of chronic cough in adults and children. Eur Respir J. 2020 Jan;55(1):1901136.[Abstract][Full Text]
Irwin RS, Baumann MH, Bolser DC, et al. Diagnosis and management of cough executive summary: ACCP evidence-based clinical practice guidelines. Chest. 2006 Jan;129(1 suppl):1S-23S.[Abstract][Full Text]
Global Initiative for Asthma. Global strategy for asthma management and prevention. 2023 [internet publication].[Full Text]
American College of Radiology. ACR Appropriateness Criteria: chronic cough. Nov 2021 [internet publication].[Abstract][Full Text]
Kahrilas PJ, Altman KW, Chang AB, et al. Chronic cough due to gastroesophageal reflux in adults: CHEST guideline and expert panel report. Chest. 2016 Dec;150(6):1341-60.[Abstract][Full Text]
1. Hermer L, Kang K, Rui P, et al. National ambulatory medical care survey - community health centers: 2014 state and national summary tables. 2019 [internet publication].[Full Text]
2. Irwin RS, French CL, Chang AB, et al. Classification of cough as a symptom in adults and management algorithms: CHEST guideline and expert panel report. Chest. 2018 Jan;153(1):196-209.[Abstract][Full Text]
3. Morice AH, Millqvist E, Bieksiene K, et al. ERS guidelines on the diagnosis and treatment of chronic cough in adults and children. Eur Respir J. 2020 Jan;55(1):1901136.[Abstract][Full Text]
4. Chang AB, Oppenheimer JJ, Irwin RS, et al. Managing chronic cough as a symptom in children and management algorithms: CHEST guideline and expert panel report. Chest. 2020 Jul;158(1):303-29.[Abstract][Full Text]
5. Kwon NH, Oh MJ, Min TH, et al. Causes and clinical features of subacute cough. Chest. 2006 May;129(5):1142-7.[Abstract][Full Text]
6. Irwin RS, Baumann MH, Bolser DC, et al. Diagnosis and management of cough executive summary: ACCP evidence-based clinical practice guidelines. Chest. 2006 Jan;129(1 suppl):1S-23S.[Abstract][Full Text]
7. Gonlugur U, Gonlugur TE. Eosinophilic bronchitis without asthma. Int Arch Allergy Immunol. 2008;147(1):1-5.[Abstract][Full Text]
8. Ramanuja S, Kelkar P. Habit cough. Ann Allergy Asthma Immunol. 2009 Feb;102(2):91-5.[Abstract]
9. Ojoo JC, Everett CF, Mulrennan SA, et al. Management of patients with chronic cough using a clinical protocol: a prospective observational study. Cough. 2013 Jan 24;9(1):2.[Abstract][Full Text]
10. Global Initiative for Asthma. Global strategy for asthma management and prevention. 2023 [internet publication].[Full Text]
11. Bangalore S, Kumar S, Messerli FH. Angiotensin-converting enzyme inhibitor associated cough: deceptive information from the Physicians' Desk Reference. Am J Med. 2010 Nov;123(11):1016-30.[Abstract][Full Text]
12. Alharbi FF, Kholod AAV, Souverein PC, et al. The impact of age and sex on the reporting of cough and angioedema with renin-angiotensin system inhibitors: a case/noncase study in VigiBase. Fundam Clin Pharmacol. 2017 Dec;31(6):676-84.[Abstract][Full Text]
13. Brugts JJ, Arima H, Remme W, et al. The incidence and clinical predictors of ACE-inhibitor induced dry cough by perindopril in 27,492 patients with vascular disease. Int J Cardiol. 2014 Oct 20;176(3):718-23.[Abstract][Full Text]
14. Braman SS. Chronic cough due to chronic bronchitis: ACCP evidence-based clinical practice guidelines. Chest. 2006 Jan;129(1 suppl):104S-15S.[Abstract][Full Text]
15. Tarlo SM, Altman KW, Oppenheimer J, et al. Occupational and environmental contributions to chronic cough in adults: chest expert panel report. Chest. 2016 Oct;150(4):894-907.[Abstract]
16. Canning BJ, Chang AB, Bolser DC, et al. Anatomy and neurophysiology of cough: CHEST Guideline and Expert Panel report. Chest. 2014 Dec;146(6):1633-48.[Abstract][Full Text]
17. Siddiq MA, Sood S, Strachan D. Pharyngeal pouch (Zenker's diverticulum). Postgrad Med J. 2001 Aug;77(910):506-11.[Abstract][Full Text]
18. Miller CP, Firoozan S, Woo EK, et al. Chronic cough: a herald symptom of thoracic aortic aneurysm in a patient with a bicuspid aortic valve. BMJ Case Rep. BMJ Case Rep. 2014 Sep 1;2014.[Abstract][Full Text]
19. Vertigan AE, Murad MH, Pringsheim T, et al. Somatic cough syndrome (previously referred to as psychogenic cough) and tic cough (previously referred to as habit cough) in adults and children: CHEST guideline and expert panel report. Chest. 2015 Jul;148(1):24-31.[Abstract][Full Text]
20. Greenhalgh T, Knight M, A'Court C, et al. Management of post-acute covid-19 in primary care. BMJ. 2020 Aug 11;370:m3026.[Abstract][Full Text]
21. National Institute for Health and Care Excellence. COVID-19 rapid guideline: managing the long-term effects of COVID-19. Dec 2020 [internet publication].[Full Text]
22. National Institute for Health and Care Excellence. Suspected cancer: recognition and referral. Oct 2023 [internet publication].[Full Text]
23. National Institute for Health and Care Excellence. Lung cancer: diagnosis and management. Jul 2023 [internet publication].[Full Text]
24. Kavanagh J, Jackson DJ, Kent BD. Over- and under-diagnosis in asthma. Breathe (Sheff). 2019 Mar;15(1):e20-7.[Abstract][Full Text]
25. British Thoracic Society; Scottish Intercollegiate Guidelines Network. British guideline on the management of asthma: a national clinical guideline. Jul 2019 [internet publication].[Full Text]
26. Louis R, Satia I, Ojanguren I, et al. European Respiratory Society guidelines for the diagnosis of asthma in adults. Eur Respir J. 2022 Feb 15:2101585.[Abstract][Full Text]
27. Metlay JP, Waterer GW, Long AC, et al. Diagnosis and treatment of adults with community-acquired pneumonia. An official clinical practice guideline of the American Thoracic Society and Infectious Diseases Society of America. Am J Respir Crit Care Med. 2019 Oct 1;200(7):e45-67.[Abstract][Full Text]
28. World Health Organization. Global tuberculosis report 2022. Oct 2022 [internet publication].[Full Text]
29. Campbell JR, Winters N, Menzies D. Absolute risk of tuberculosis among untreated populations with a positive tuberculin skin test or interferon-gamma release assay result: systematic review and meta-analysis. BMJ. 2020 Mar 10;368:m549.[Abstract][Full Text]
30. Gibson P, Wang G, McGarvey L, et al. Treatment of unexplained chronic cough: CHEST guideline and expert panel report. Chest. 2016 Jan;149(1):27-44.[Abstract][Full Text]
31. American College of Radiology. ACR Appropriateness Criteria: chronic cough. Nov 2021 [internet publication].[Abstract][Full Text]
32. Leconte S, Ferrant D, Dory V, et al. Validated methods of cough assessment: a systematic review of the literature. Respiration. 2011;81(2):161-74.[Abstract][Full Text]
33. Lin L, Poh KL, Lim TK. Empirical treatment of chronic cough: a cost-effectiveness analysis. Proc AMIA Symp. 2001:383-7.[Abstract][Full Text]
34. Kuzniar TJ, Morgenthaler TI, Afessa B, et al. Chronic cough from the patient's perspective. Mayo Clin Proc. 2007 Jan;82(1):56-60.[Abstract]
35. McGarvey LP, Heaney LG, Lawson JT, et al. Evaluation and outcome of patients with chronic non-productive cough using a comprehensive diagnostic protocol. Thorax. 1998 Sep;53(9):738-43.[Abstract][Full Text]
36. Côté A, Russell RJ, Boulet LP, et al. Managing chronic cough due to asthma and NAEB in adults and adolescents: CHEST guideline and expert panel report. Chest. 2020 Jul;158(1):68-96.[Abstract][Full Text]
37. Pratter MR. Chronic upper airway cough syndrome secondary to rhinosinus diseases (previously referred to as postnasal drip syndrome): ACCP evidence-based clinical practice guidelines. Chest. 2006 Jan;129(1 suppl):63S-71.[Abstract][Full Text]
38. Irwin RS, French CL, Curley FJ, et al. Chronic cough due to gastroesophageal reflux. Clinical, diagnostic, and pathogenetic aspects. Chest. 1993 Nov;104(5):1511-7.[Abstract][Full Text]
39. Chen JW, Vela MF, Peterson KA, et al. AGA clinical practice update on the diagnosis and management of extraesophageal gastroesophageal reflux disease: expert review. Clin Gastroenterol Hepatol. 2023 Jun;21(6):1414-21.e3.[Abstract][Full Text]
40. Dicpinigaitis PV. Angiotensin-converting enzyme inhibitor-induced cough: ACCP evidence-based clinical practice guidelines. Chest. 2006 Jan;129(1 suppl):169S-73.[Abstract][Full Text]
41. Katz PO, Dunbar KB, Schnoll-Sussman FH, et al. ACG clinical guideline for the diagnosis and management of gastroesophageal reflux disease. Am J Gastroenterol. 2022 Jan 1;117(1):27-56.[Abstract]
42. Kahrilas PJ, Altman KW, Chang AB, et al. Chronic cough due to gastroesophageal reflux in adults: CHEST guideline and expert panel report. Chest. 2016 Dec;150(6):1341-60.[Abstract][Full Text]
43. Faruqi S, Molyneux ID, Fathi H, et al. Chronic cough and esomeprazole: a double-blind placebo-controlled parallel study. Respirology. 2011 Oct;16(7):1150-6.[Abstract]
44. British Thoracic Society and Scottish Intercollegiate Guidelines Network. British guideline on the management of asthma. July 2019 [internet publication].[Full Text]
45. Chang AB, Bell SC, Byrnes CA, et al. Chronic suppurative lung disease and bronchiectasis in children and adults in Australia and New Zealand: a position statement from the Thoracic Society of Australia and New Zealand and the Australian Lung Foundation. Med J Aust. 2010 Sep 20;193(6):356-65.[Abstract][Full Text]
46. Bucca C, Culla B, Brussino L, et al. Effect of iron supplementation in women with chronic cough and iron deficiency. Int J Clin Pract. 2012 Nov;66(11):1095-100.[Abstract]
47. Murry T, Sapienza C. The role of voice therapy in the management of paradoxical vocal fold motion, chronic cough, and laryngospasm. Otolaryngol Clin North Am. 2010 Feb;43(1):73-83.[Abstract]
48. Simundic AM, Bölenius K, Cadamuro J, et al. Joint EFLM-COLABIOCLI recommendation for venous blood sampling. Clin Chem Lab Med. 2018;56(12):2015-38.[Abstract]
49. National Asthma Education and Prevention Program. Expert panel report 3: guidelines for the diagnosis and management of asthma: full report 2007. Aug 2007 [internet publication].[Full Text]
50. Expert Panel Working Group of the National Heart, Lung, and Blood Institute (NHLBI) administered and coordinated National Asthma Education and Prevention Program Coordinating Committee (NAEPPCC)., Cloutier MM, Baptist AP, et al. 2020 Focused updates to the asthma management guidelines: a report from the National Asthma Education and Prevention Program Coordinating Committee Expert Panel Working Group. J Allergy Clin Immunol. 2020 Dec;146(6):1217-70.[Abstract][Full Text]
51. Chatkin JM, Ansarin K, Silkoff PE, et al. Exhaled nitric oxide as a noninvasive assessment of chronic cough. Am J Respir Crit Care Med. 1999 Jun;159(6):1810-3.[Full Text]
52. Cockcroft DW. Direct challenge tests: airway hyperresponsiveness in asthma: its measurement and clinical significance. Chest. 2010 Aug;138(2 suppl):18S-24.[Abstract]
53. Brightling CE. Chronic cough due to nonasthmatic eosinophilic bronchitis: ACCP evidence-based clinical practice guidelines. Chest. 2006 Jan;129(1 suppl):116S-21.[Abstract][Full Text]
54. Berlyne GS, Parameswaran K, Kamada D, et al. A comparison of exhaled nitric oxide and induced sputum as markers of airway inflammation. J Allergy Clin Immunol. 2000 Oct;106(4):638-44.[Abstract]
55. Global Initiative for Chronic Obstructive Lung Disease. Global strategy for prevention, diagnosis and management of COPD: 2024 report. 2023 [internet publication].[Full Text]
56. Chotas HG, Ravin CE. Chest radiography: estimated lung volume and projected area obscured by heart, mediastinum and diaphragm. Radiology. 1994 Nov;193(2):403-4.[Abstract]
57. British Thoracic Society. BTS guideline for bronchiectasis in adults. December 2018 [internet publication].[Full Text]
58. Ebell MH, Bentivegna M, Cai X, et al. Accuracy of biomarkers for the diagnosis of adult community-acquired pneumonia: a meta-analysis. Acad Emerg Med. 2020 Mar;27(3):195-206.[Abstract][Full Text]
59. Braman SS. Postinfectious cough: ACCP evidence-based clinical practice guidelines. Chest. 2006 Jan;129(1 suppl):138S-46.[Abstract][Full Text]
60. Lewinsohn DM, Leonard MK, LoBue PA, et al. Official American Thoracic Society/Infectious Diseases Society of America/Centers for Disease Control and Prevention clinical practice guidelines: diagnosis of tuberculosis in adults and children. Clin Infect Dis. 2017 Jan 15;64(2):e1-33.[Abstract][Full Text]
61. Geldmacher H, Taube C, Kroeger C, et al. Assessment of lymph node tuberculosis in northern Germany: a clinical review. Chest. 2002 Apr;121(4):1177-82.[Abstract]
62. Weir MR, Thornton GF. Extrapulmonary tuberculosis. Experience of a community hospital and review of the literature. Am J Med. 1985 Oct;79(4):467-78.[Abstract]
63. Baydur A. The spectrum of extrapulmonary tuberculosis. West J Med. 1977 Apr;126(4):253-62.[Abstract][Full Text]
64. Centers for Disease Control and Prevention. Updated guidelines for the use of nucleic acid amplification tests in the diagnosis of tuberculosis. Jan 2009 [internet publication].[Full Text]
65. World Health Organization. WHO consolidated guidelines on tuberculosis Module 3: Diagnosis - Rapid diagnostics for tuberculosis detection. Mar 2024 [internet publication].[Full Text]
66. Bjerrum S, Schiller I, Dendukuri N, et al. Lateral flow urine lipoarabinomannan assay for detecting active tuberculosis in people living with HIV. Cochrane Database Syst Rev. 2019 Oct 21;10(10):CD011420.[Abstract][Full Text]
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