Highlights & Basics
- Childhood constipation is typically characterized by infrequent bowel evacuations, large stools, and difficult or painful defecation.
- Symptoms often result from low fiber, poor nutrient, poor stooling technique, and/or insufficient water intake, which leads to excessive hardening of the stool. This often starts as an acute problem but can progress to fecal impaction and chronic constipation.
- Particularly in young children, any cause of painful defecation may provoke active withholding. Withholding may worsen the constipation and lead to a vicious cycle.
- Duration of constipation and amount of stool burden may depend on capacity of the child's rectum, the degree of rectal dilation (if excessive, often called megarectum), and other factors including rectal sensory function.
- After fecal disimpaction, maintenance stool softeners are essential and are often required for many months or years to reduce relapse risk.
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Citations
Rubin G, Dale A. Chronic constipation in children. BMJ. 2006 Nov 18;333(7577):1051-5.[Abstract][Full Text]
Mulhem E, Khondoker F, Kandiah S. Constipation in children and adolescents: evaluation and treatment. Am Fam Physician. 2022 May 1;105(5):469-78.[Abstract]
Benninga MA, Faure C, Hyman PE, et al. Childhood functional gastrointestinal disorders: neonate/toddler. Gastroenterology. 2016 Feb 15 [Epub ahead of print].[Abstract]
Hyams JS, Di Lorenzo C, Saps M, et al. Functional disorders: children and adolescents. Gastroenterology. 2016 Feb 15 [Epub ahead of print].[Abstract]
National Institute for Health and Care Excellence. Constipation in children and young people: diagnosis and management. Jul 2017 [internet publication].[Full Text]
1. Rubin G, Dale A. Chronic constipation in children. BMJ. 2006 Nov 18;333(7577):1051-5.[Abstract][Full Text]
2. Peeters B, Noens I, Philips EM, et al. Autism spectrum disorders in children with functional defecation disorders. J Pediatr. 2013 Sep;163(3):873-8.[Abstract]
3. McKeown C, Hisle-Gorman E, Eide M, et al. Association of constipation and fecal incontinence with attention-deficit/hyperactivity disorder. Pediatrics. 2013 Nov;132(5):e1210-5.[Abstract]
4. Waterham M, Kaufman J, Gibb S. Childhood constipation. Aust Fam Physician. 2017 Dec;46(12):908-12.[Abstract][Full Text]
5. van den Berg MM, Benninga MA, Di Lorenzo C. Epidemiology of childhood constipation: a systematic review. Am J Gastroenterol. 2006 Oct;101(10):2401-9.[Abstract]
6. Loening-Baucke V. Prevalence rates for constipation and faecal and urinary incontinence. Arch Dis Child. 2007 Jun;92(6):486-9.[Abstract][Full Text]
7. Lee WT, Ip KS, Chan JS, et al. Increased prevalence of constipation in pre-school children is attributable to under-consumption of plant foods: A community-based study. J Paediatr Child Health. 2008 Apr;44(4):170-5.[Abstract]
8. Froon-Torenstra D, Beket E, Khader AM, et al. Prevalence of functional constipation among Palestinian preschool children and the relation to stressful life events. PLoS One. 2018;13(12):e0208571.[Abstract][Full Text]
9. Corazziari E, Staiano A, Miele E, et al. Bowel frequency and defecatory patterns in children: a prospective nationwide survey. Clin Gastroenterol Hepatol. 2005 Nov;3(11):1101-6.[Abstract][Full Text]
10. Borowitz SM, Cox DJ, Kovatchev B, et al. Treatment of childhood constipation by primary care physicians: efficacy and predictors of outcome. Pediatrics. 2005 Apr;115(4):873-7.[Abstract]
11. Sommers T, Corban C, Sengupta N, et al. Emergency department burden of constipation in the United States from 2006 to 2011. Am J Gastroenterol. 2015 Apr;110(4):572-9.[Abstract]
12. Walter AW, Hovenkamp A, Devanarayana NM, et al. Functional constipation in infancy and early childhood: epidemiology, risk factors, and healthcare consultation. BMC Pediatr. 2019 Aug 15;19(1):285.[Abstract][Full Text]
13. Mulhem E, Khondoker F, Kandiah S. Constipation in children and adolescents: evaluation and treatment. Am Fam Physician. 2022 May 1;105(5):469-78.[Abstract]
14. Partin JC, Hamill SK, Fischel JE, et al. Painful defecation and fecal soiling in children. Pediatrics. 1992 Jun;89(6 Pt 1):1007-9.[Abstract]
15. Comas Vives A, Polanco Allue I. Case-control study of risk factors associated with constipation. The FREI Study [in Spanish]. An Pediatr (Barc). 2005 Apr;62(4):340-5.[Abstract]
16. Kokx MO, Comstock JA, Facklam RR. Streptococcal perianal disease in children. Pediatrics. 1987 Nov;80(5):659-63.[Abstract]
17. Iacono G, Carroccio A, Cavataio F, et al. Chronic constipation as a symptom of cow milk allergy. J Pediatr. 1995 Jan;126(1):34-9.[Abstract]
18. Iacono G, Bonventre S, Scalici C, et al. Food intolerance and chronic constipation: manometry and histology study. Eur J Gastroenterol Hepatol. 2006 Feb;18(2):143-50.[Abstract]
19. Carroccio A, Iacono G. Review article: Chronic constipation and food hypersensitivity - an intriguing relationship. Aliment Pharmacol Ther. 2006 Nov 1;24(9):1295-304.[Abstract]
20. Finkel MA. Anogenital trauma in sexually abused children. Pediatrics. 1989 Aug;84(2):317-22.[Abstract]
21. Baroud E, Zar-Kessler C, Bender S. A child psychiatry perspective on encopresis. J Am Acad Child Adolesc Psychiatry. 2022 Jul;61(7):851-3.[Abstract]
22. Arden NH, Patriarca PA, Fasano MB, et al. The roles of vaccination and amantadine prophylaxis in controlling an outbreak of influenza A (H3N2) in a nursing home. Arch Intern Med. 1988 Apr;148(4):865-8.[Abstract]
23. Roma E, Adamidis D, Nikolara R, et al. Diet and chronic constipation in children: the role of fiber. J Pediatr Gastroenterol Nutr. 1999 Feb;28(2):169-74.[Abstract]
24. Loening-Baucke V. Urinary incontinence and urinary tract infection and their resolution with treatment of chronic constipation of childhood. Pediatrics. 1997 Aug;100(2 Pt 1):228-32.[Abstract]
25. Philips EM, Peeters B, Teeuw AH, et al. Stressful life events in children with functional defecation disorders. J Pediatr Gastroenterol Nutr. 2015 Oct;61(4):384-92.[Abstract]
26. Fishman L, Lenders C, Fortunato C, et al. Increased prevalence of constipation and fecal soiling in a population of obese children. J Pediatr. 2004 Aug;145(2):253-4.[Abstract]
27. Cunningham C, Taylor HG, Minich NM, et al. Constipation in very-low-birth-weight children at 10 to 14 years of age. J Pediatr Gastroenterol Nutr. 2001 Jul;33(1):23-7.[Abstract]
28. Paul SP, Broad SR, Spray C. Idiopathic constipation in children clinical practice guidelines. Arch Dis Child Educ Pract Ed. 2016 Apr;101(2):65-9.[Abstract]
29. Heron J, Grzeda M, Tappin D, et al. Early childhood risk factors for constipation and soiling at school age: an observational cohort study. BMJ Paediatr Open. 2018;2(1):e000230.[Abstract][Full Text]
30. Borowitz SM, Cox DJ, Tam A, et al. Precipitants of constipation during early childhood. J Am Board Fam Pract. 2003 May-Jun;16(3):213-8.[Abstract][Full Text]
31. Young RJ, Beerman LE, Vanderhoof JA. Increasing oral fluids in chronic constipation in children. Gastroenterol Nurs. 1998 Jul-Aug;21(4):156-61.[Abstract]
32. Papadopoulou A. Clayden GS, Booth IW. The clinical value of solid marker transit studies in childhood constipation and soiling. Eur J Pediatr. 1994 Aug;153(8):560-4.[Abstract]
33. Di Pace MR, Catalano P, Caruso AM, et al. Is rectal disimpact always necessary in children with chronic constipation? Evaluation with pelvic ultrasound. Pediatr Surg Int. 2010 Jun;26(6):601-6.[Abstract]
34. Reid JR, Buonomo C, Moreira C, et al. The barium enema in constipation: comparison with rectal manometry and biopsy to exclude Hirschsprung's disease after the neonatal period. Pediatr Radiol. 2000 Oct;30(10):681-4.[Abstract]
35. Berger MY, Tabbers MM, Kurver MJ, et al. Value of abdominal radiography, colonic transit time, and rectal ultrasound scanning in the diagnosis of idiopathic constipation in children: a systematic review. J Pediatr. 2012 Jul;161(1):44-50.e1-2.[Abstract][Full Text]
36. Benninga MA, Faure C, Hyman PE, et al. Childhood functional gastrointestinal disorders: neonate/toddler. Gastroenterology. 2016 Feb 15 [Epub ahead of print].[Abstract]
37. Hyams JS, Di Lorenzo C, Saps M, et al. Functional disorders: children and adolescents. Gastroenterology. 2016 Feb 15 [Epub ahead of print].[Abstract]
38. National Institute for Health and Care Excellence. Constipation in children and young people: diagnosis and management. Jul 2017 [internet publication].[Full Text]
39. Tabbers MM, DiLorenzo C, Berger MY, et al. Evaluation and treatment of functional constipation in infants and children: evidence-based recommendations from ESPGHAN and NASPGHAN. J Pediatr Gastroenterol Nutr. 2014 Feb;58(2):258-74.[Abstract]
40. Benninga M, Candy DC, Catto-Smith AG, et al. The Paris Consensus on Childhood Constipation Terminology (PACCT) Group. J Pediatr Gastroenterol Nutr. 2005 Mar;40(3):273-5.[Abstract][Full Text]
41. World Gastroenterology Organisation Global guidelines. Constipation: a global perspective. Nov 2010 [internet publication].[Full Text]
42. Clayden GS, Keshtgar AS, Carcani-Rathwell I, et al. The management of chronic constipation and related faecal incontinence in childhood. Arch Dis Child Ed Pract. 2005;90:ep58-67.[Full Text]
43. Tabbers MM, Boluyt N, Berger MY, et al. Nonpharmacologic treatments for childhood constipation: systematic review. Pediatrics. 2011 Oct;128(4):753-61.[Abstract]
44. Gordon M, MacDonald JK, Parker CE, et al. Osmotic and stimulant laxatives for the management of childhood constipation. Cochrane Database Syst Rev. 2016;(8):CD009118.[Abstract][Full Text]
45. Lee-Robichaud H, Thomas K, Morgan J, et al. Lactulose versus polyethylene glycol for chronic constipation. Cochrane Database Syst Rev. 2010 Jul 7;(7):CD007570.[Abstract][Full Text]
46. Zurad EG, Johanson JF. Over-the-counter laxative polyethylene glycol 3350: an evidence-based appraisal. Curr Med Res Opin. 2011 Jul;27(7):1439-52.[Abstract]
47. Wang Y, Wang B, Jiang X, et al. Polyethylene glycol 4000 treatment for children with constipation: a randomized comparative multicenter study. Exp Ther Med. 2012 May;3(5):853-6.[Abstract][Full Text]
48. Gomes PB, Duarte MA, Melo Mdo C. Comparison of the effectiveness of polyethylene glycol 4000 without electrolytes and magnesium hydroxide in the treatment of chronic functional constipation in children. J Pediatr (Rio J). 2011 Jan-Feb;87(1):24-8.[Abstract]
49. Mendoza J, Legido J, Rubio S, et al. Systematic review: the adverse effects of sodium phosphate enema. Aliment Pharmacol Ther. 2007 Jul 1;26(1):9-20.[Abstract][Full Text]
50. Candy DC, Edwards D, Geraint M. Treatment of faecal impaction with polyethylene glycol plus electrolytes (PEG + E) followed by a double-blind comparison of PEG + E versus lactulose as maintenance therapy. J Pediatr Gastroenterol Nutr. 2006 Jul;43(1):65-70.[Abstract]
51. Zar-Kessler C, Kuo B, Cole E, et al. Benefit of pelvic floor physical therapy in pediatric patients with dyssynergic defecation constipation. Dig Dis. 2019;37(6):478-85.[Abstract][Full Text]
52. Church JT, Simha S, Wild LC, et al. Antegrade continence enemas improve quality of life in patients with medically-refractory encopresis. J Pediatr Surg. 2017 May;52(5):778-82.[Abstract]
53. Caruso AM, Milazzo MPM, Bommarito D, et al. Advanced management protocol of transanal irrigation in order to improve the outcome of pediatric patients with fecal incontinence. Children (Basel). 2021 Dec 11;8(12):1174.[Abstract][Full Text]
54. US Food and Drug Administration. FDA warns of possible harm from exceeding recommended dose of over-the-counter sodium phosphate products to treat constipation. January 2014 [internet publication].[Full Text]
55. van Mill MJ, Koppen IJN, Benninga MA. Controversies in the management of functional constipation in children. Curr Gastroenterol Rep. 2019 Apr 25;21(6):23.[Abstract][Full Text]
56. Hoffman JM, Tyler K, MacEachern SJ, et al. Activation of colonic mucosal 5-HT(4) receptors accelerates propulsive motility and inhibits visceral hypersensitivity. Gastroenterology. 2012 Apr;142(4):844-54.e4.[Abstract][Full Text]
57. Mugie SM, Korczowski B, Bodi P, et al. Prucalopride is no more effective than placebo for children with functional constipation. Gastroenterology. 2014 Dec;147(6):1285-95.e1.[Abstract][Full Text]
58. Hussain SZ, Labrum B, Mareya S, et al. Safety of lubiprostone in pediatric patients with functional constipation: a nonrandomized, open-label Trial. J Pediatr Gastroenterol Nutr. 2021 Nov 1;73(5):572-8.[Abstract][Full Text]
59. Hyman PE, Di Lorenzo C, Prestridge LL, et al. Lubiprostone for the treatment of functional constipation in children. J Pediatr Gastroenterol Nutr. 2014 Mar;58(3):283-91.[Abstract][Full Text]
60. Benninga MA, Hussain SZ, Sood MR, et al. Lubiprostone for pediatric functional constipation: randomized, controlled, double-blind study with long-term extension. Clin Gastroenterol Hepatol. 2022 Mar;20(3):602-10.e5.[Abstract][Full Text]
61. Halleran DR, Lu PL, Ahmad H, et al. Anal sphincter botulinum toxin injection in children with functional anorectal and colonic disorders: a large institutional study and review of the literature focusing on complications. J Pediatr Surg. 2019 Nov;54(11):2305-10.[Abstract]
62. Zar-Kessler C, Kuo B, Belkind-Gerson J. Botulinum toxin injection for childhood constipation is safe and can be effective regardless of anal sphincter dynamics. J Pediatr Surg. 2018 Apr;53(4):693-7.[Abstract]
63. Wallace C, Sinopoulou V, Gordon M, et al. Probiotics for treatment of chronic constipation in children. Cochrane Database Syst Rev. 2022 Mar 29;3(3):CD014257.[Abstract][Full Text]
64. Lu ML, He J, Lu S. Electrical stimulation therapy for slow transit constipation in children: a systematic review. Int J Colorectal Dis. 2015 May;30(5):697-702.[Abstract]
65. Sulkowski JP, Nacion KM, Deans KJ, et al. Sacral nerve stimulation: a promising therapy for fecal and urinary incontinence and constipation in children. J Pediatr Surg. 2015 Oct;50(10):1644-7.[Abstract]
66. Besendörfer M, Kohl M, Schellerer V, et al. A pilot study of non-invasive sacral nerve stimulation in treatment of constipation in childhood and adolescence. Front Pediatr. 2020;8:169.[Abstract][Full Text]
67. van Ginkel R, Reitsma JB, Büller HA, et al. Childhood constipation: longitudinal follow-up beyond puberty. Gastroenterology. 2003 Aug;125(2):357-63.[Abstract]
68. Staiano A, Andreotti MR, Greco L, et al. Long-term follow-up of children with chronic idiopathic constipation. Dig Dis Sci. 1994 Mar;39(3):561-4.[Abstract]
69. Zanetti G, Marchiori E, Gasparetto TD, et al. Lipoid pneumonia in children following aspiration of mineral oil used in the treatment of constipation: high-resolution CT findings in 17 patients. Pediatric Radiol. 2007 Nov;37(11):1135-9.[Abstract]
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