Highlights & Basics
- Chronic kidney disease (CKD) is a common condition that is often unrecognized until the most advanced stages.
- Diagnosis is determined only by laboratory studies: proteinuria or hematuria, and/or a reduction in the glomerular filtration rate, for more than 3 months' duration.
- The most common causes are diabetes mellitus and hypertension.
- Glycemic control for diabetic kidney disease and optimization of blood pressures are key in slowing the progression of the disease. Use of agents that block the renin-angiotensin system and sodium-glucose cotransporter-2 (SGLT2) inhibitors have kidney function preserving benefits that are independent of blood pressure and glucose control.
- CKD is a risk factor for cardiovascular disease, independent of comorbidities such as diabetes, hypertension, and dyslipidemia.
Quick Reference
History & Exam
Key Factors
Other Factors
Diagnostics Tests
Treatment Options
Definition
Epidemiology
Etiology
Pathophysiology
Citations
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National Institute for Health and Care Excellence. Chronic kidney disease: assessment and management. 2021 [internet publication]. [Full Text]
Expert Panel on Urologic Imaging., Wong-You-Cheong JJ, Nikolaidis P, et al. ACR Appropriateness Criteria® Renal Failure. J Am Coll Radiol. 2021 May;18(5s):S174-S188.[Abstract][Full Text]
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