Highlights & Basics
- Bed bugs are nocturnal, obligate, blood-feeding parasites that take refuge in furniture and bedding.
- Bites are painless, but cause discomfort owing to the associated reactions.
- Characteristic lesions are pruritic papules in an irregular linear pattern, typically found on body surfaces exposed during sleeping such as face, neck, arms, legs, and shoulders.
- Treatment is symptomatic and includes antihistamines, topical antipruritics, and topical corticosteroids. In severe cases, systemic corticosteroids may be necessary.
- Elimination from the home is essential and may require professional extermination.
Quick Reference
History & Exam
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Definition
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Citations
Parola P, Izri A. Bedbugs. N Engl J Med. 2020 Jun 4;382(23):2230-7.
McNeill C, Jarrett A, Shreve DM, et al. Bed bugs: current treatment guidelines. J Nurse Pract. 2017 Jun;13(6): P381-8.[Full Text]
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7. McNeill C, Jarrett A, Shreve DM, et al. Bed bugs: current treatment guidelines. J Nurse Pract. 2017 Jun;13(6): P381-8.[Full Text]
8. Heymann WR. Bedbugs: a new morning for the nighttime pests. J Am Acad Dermatol. 2009 Mar;60(3):482-3.[Abstract]
9. Potter M; University of Kentucky College of Agriculture, Food and Environment. Bed bugs. 2020 [internet publication].[Full Text]
10. Delaunay P. Human travel and traveling bedbugs. J Travel Med. 2012 Dec;19(6):373-9.[Abstract][Full Text]
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13. Doggett SL, Lee CY. Historical and contemporary control options against bed bugs, Cimex spp. Annu Rev Entomol. 2023 Jan 23;68:169-90.[Abstract][Full Text]
14. NYC Environment & Health Data Portal. Adults reporting bed bugs in their home. 2014 [internet publication].[Full Text]
15. Anses. Bed bugs are a financial burden and reduce quality of life for many people in France. Jul 2023 [internet publication].[Full Text]
16. Doggett SL. A code of practice for the control of bed bug infestations in Australia. 4th edition. March 2013 [internet publication].[Full Text]
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20. Aoki V, Millikan RC, Diaz LA, et al. Environmental risk factors in pemphigus foliaceus (fogo selvagem). J Investig Dermatol Symp Proc. 2004 Jan;9(1):34-40.[Abstract][Full Text]
21. Centers for Disease Control and Prevention. CDC Yellow Book 2024: health information for international travel. Section 4: mosquitoes, ticks and other arthropods - bed bugs. May 2023 [internet publication].[Full Text]
22. Krause-Parello CA, Sciscione P. Bedbugs: an equal opportunist and cosmopolitan creature. J Sch Nurs. 2009 Apr;25(2):126-32.[Abstract]
23. United States Environmental Protection Agency. Bed bugs: get them out and keep them out. Jul 2024 [internet publication].[Full Text]
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25. British Pest Control Association. Pest advice for controlling bed bugs [internet publication].[Full Text]
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28. Sheele JM, Pritt BS, Libertin CR, et al. Bed bugs are associated with anemia. Am J Emerg Med. 2021 Aug;46:482-8.[Abstract]
29. Elder DE, Elenitsas R, Rosenbach M, et al. Lever's histopathology of the skin. 11th ed. Philadelphia, PA: Lippincott, Williams & Wilkins; 2014.
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32. US Environmental Protection Agency. Bed bug clearinghouse by audience [internet publication].[Full Text]
33. Scarupa MD, Economides A. Bedbug bites masquerading as urticaria. J Allergy Clin Immunol. 2006 Jun;117(6):1508-9.[Abstract][Full Text]
34. Moore DJ, Miller DM. Laboratory evaluations of insecticide product efficacy for control of Cimex lentularius. J Econ Entomol. 2006 Dec;99(6):2080-6.[Abstract]
35. Myamba J, Maxwell CA, Asidi A, et al. Pyrethroid resistance in tropical bedbugs, Cimex hemipterus, associated with use of treated bednets. Med Vet Entomol. 2002 Dec;16(4):448-51.[Abstract]
36. Sheele JM, Ridge G, Li X, et al. The benefit of a single oral dose of ivermectin in humans: the adverse effects on cimex lectularius L. populations and fecundity. Cureus. 2019 Nov 8;11(11):e6098.[Abstract][Full Text]
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38. Fletcher CL, Ardern-Jones MR, Hay RJ. Widespread bullous eruption due to multiple bed bug bites. Clin Exp Dermatol. 2002 Jan;27(1):74-5.[Abstract]
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40. Silverman AL, Qu LH, Walker ED, et al. Assessment of hepatitis B virus DNA and hepatitis C virus RNA in the common bedbug (Cimex Lectularius L.) and kissing bug (Rodnius prolixus). Am J Gastroenterol. 2001 Jul;96(7):2194-8.[Abstract]
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43. Herrera AL, Chaussee MS, Pietri JE. Experimental acquisition, maintenance, and transmission of methicillin-resistant Staphylococcus aureus by the common bed bug, Cimex lectularius. J Infect Dis. 2024 Jan 12;229(1):245-51.[Abstract]
44. Lai O, Ho D, Glick S, et al. Bed bugs and possible transmission of human pathogens: a systematic review. Arch Dermatol Res. 2016 Oct;308(8):531-8.[Abstract][Full Text]
45. Hildreth CJ, Burke AE, Glass RM. JAMA patient page: bed bugs. JAMA. 2009 Apr 1;301(13):1398.[Abstract][Full Text]
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