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Highlights & Basics
- Wrinkles are visible lines or creases on the surface of the skin associated with aging. They commonly occur on sun-exposed areas of the body (i.e., face, neck, decolletage, dorsum of hands).
- Their development is mainly determined by genetic predisposition, environmental factors, and skin type. Environmental factors that promote wrinkling over the course of many years include ultraviolet light exposure (photoaging) and smoking. Prevention with lifestyle modifications and sun avoidance is critical in mitigating wrinkle formation.
- Wrinkles can be divided into 2 categories, fine and deep lines, and classified as atrophic, elastotic, expressional, and gravitational. Each type develops in specific areas and is characterized by distinct cutaneous alterations.
- Treatments include topical treatments (antioxidants, tretinoin), cosmetic procedures (fillers, botulinum toxin injections, chemical peels), and surgical procedures (laser resurfacing, dermabrasion, rhytidectomy).
- Treatments are generally more effective for fine wrinkles, which can respond to topical or minimally invasive procedures. Deep wrinkles tend to require more aggressive techniques, such as ablative laser resurfacing or surgical procedures.
Quick Reference
History & Exam
Key Factors
Other Factors
Diagnostics Tests
Treatment Options
Definition
Epidemiology
Etiology
Pathophysiology
Images
50-year-old woman with photoaged skin showing advanced wrinkles, discoloration of the skin, actinic keratoses, and dynamic forces affecting the skin
30-year-old woman with mild wrinkles showing few wrinkles at rest
30-year-old woman with mild wrinkles showing moderate wrinkles on major facial activity
80-year-old woman with severe wrinkles, photoaging, and gravitational forces affecting the skin
Citations
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