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Highlights & Basics
- An intrinsic acute kidney injury caused by ischemic or nephrotoxic injury to renal tubular epithelial cells, which results in tubular dysfunction or detachment from the basement membrane.
- A history of hypotension, fluid depletion, or exposure to nephrotoxic agents is usually present.
- In otherwise healthy individuals, when the underlying insult is corrected, the patient frequently has a good outcome with complete renal recovery.
- There is no specific therapy for acute tubular necrosis apart from supportive care.
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Citations
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