Summary
Acute vision loss
Chronic vision loss
Systemic considerations
Library
Corneal ulcer with epithelial defect and stromal infiltrate
Central retinal vein occlusion: extensive retinal hemorrhages and dilated vessels
Typical white matter lesions indicative of multiple sclerosis risk (MRI)
Segmental optic disk swelling and hemorrhage seen in nonarteritic ischemic optic neuropathy
Angle-closure glaucoma: the pupil is mid-dilated, and the cornea is edematous and cloudy, as indicated by the dulled and irregular light reflex
Pituitary apoplexy: large suprasellar mass with heterogeneous gadolinium enhancement (T1-weighted MRI)
Pituitary tumor: homogenous suprasellar mass elevating and compressing optic chiasm (MRI)
Subretinal hemorrhage and retinal elevation from subfoveal neovascularization
Fluorescein angiogram showing classic choroidal neovascularization with early hyperfluorescence
Right eye of patient with homonymous field defect
Left eye of patient with homonymous field defect
Right optic nerve with disk swelling
Citations
Rossi T, Boccassini B, Iossa M, et al. Triaging and coding ophthalmic emergency: the Rome Eye Scoring System for Urgency and Emergency (RESCUE): a pilot study of 1,000 eye-dedicated emergency room patients. Eur J Ophthalmol. 2007 May-Jun;17(3):413-7.[Abstract]
Bird AC, Bressler NM, Bressler SB, et al. An international classification and grading system for age-related maculopathy and age-related macular degeneration. Surv Ophthalmol. 1995 Mar-Apr;39(5):367-74.[Abstract]
Donahue SP, Baker CN; American Academy of Pediatrics; American Association of Certified Orthoptists; American Association for Pediatric Ophthalmology and Strabismus; American Academy of Ophthalmology. Procedures for the evaluation of the visual system by pediatricians. Pediatrics. 2016 Jan;137(1). (Reaffirmed Feb 2022).[Abstract][Full Text]
1. World Health Organization. Blindness and vision impairment. Oct 2022 [internet publication].[Full Text]
2. GBD 2019 Blindness and Vision Impairment Collaborators; Vision Loss Expert Group of the Global Burden of Disease Study. Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for the Global Burden of Disease Study. Lancet Glob Health. 2021 Feb;9(2):e144-60.[Abstract][Full Text]
3. Rossi T, Boccassini B, Iossa M, et al. Triaging and coding ophthalmic emergency: the Rome Eye Scoring System for Urgency and Emergency (RESCUE): a pilot study of 1,000 eye-dedicated emergency room patients. Eur J Ophthalmol. 2007 May-Jun;17(3):413-7.[Abstract]
4. Ramos M, Kruger EF, Lashkari K. Biostatistical analysis of pseudophakic and aphakic retinal detachments. Semin Ophthalmol. 2002 Sep-Dec;17(3-4):206-13.[Abstract]
5. Klig JE. Ophthalmologic complications of systemic disease. Emerg Med Clin North Am. 2008 Feb;26(1):217-31.[Abstract]
6. De Silva I, Thomas MG, Shirodkar AL, et al; BEECS Study Group, Buchan J, Verma S. Patterns of attendances to the hospital emergency eye care service: a multicentre study in England. Eye (Lond). 2021 Nov 30:1-8.[Abstract][Full Text]
7. Fea A, Bosone A, Rolle T, et al. Eye injuries in an Italian urban population: report of 10,620 cases admitted to an eye emergency department in Torino. Graefes Arch Clin Exp Ophthalmol. 2008 Feb;246(2):175-9.[Abstract]
8. Galindo-Ferreiro A, Sanchez-Tocino H, Varela-Conde Y, et al. Ocular emergencies presenting to an emergency department in Central Spain from 2013 to 2018. Eur J Ophthalmol. 2021 Mar;31(2):748-53.[Abstract]
9. Jones HL, Walker EA, Schechter CB, et al. Vision is precious: a successful behavioral intervention to increase the rate of screening for diabetic retinopathy for inner-city adults. Diabetes Educ. 2010 Jan-Feb;36(1):118-26.[Abstract][Full Text]
10. Solomon SD, Chew E, Duh EJ, et al. Diabetic retinopathy: a position statement by the American Diabetes Association. Diabetes Care. 2017 Mar;40(3):412-8.[Abstract][Full Text]
11. Mitra A, Chavan R, Gunda M. Occult giant cell arteritis and steroid therapy: how urgent is urgent? Ann Ophthalmol (Skokie). 2006 Winter;38(4):343-5.[Abstract]
12. Chidambaram JD. Recent advances in the diagnosis and management of bacterial keratitis. Int Ophthalmol Clin. 2007 Summer;47(3):1-6.[Abstract]
13. Beck RW, Trobe JD, Moke PS, et al. High- and low-risk profiles for the development of multiple sclerosis within 10 years after optic neuritis: experience of the optic neuritis treatment trial. Arch Ophthalmol. 2003 Jul;121(7):944-9.[Abstract]
14. National Institute for Health and Care Excellence. Glaucoma: diagnosis and management. Jan 2022 [internet publication].[Full Text]
15. National Health and Medical Research Council. Systematic literature review on the detection, diagnosis, management and prevention of glaucoma. Jun 2009 [internet publication].[Full Text]
16. Dayan M, Turner B, McGhee C. Acute angle closure glaucoma masquerading as systemic illness. BMJ. 1996 Aug 17;313(7054):413-5.[Abstract][Full Text]
17. Mitchell P, Liew G, Gopinath B, et al. Age-related macular degeneration. Lancet. 2018 Sep 29;392(10153):1147-59.[Abstract][Full Text]
18. Hollands H, Johnson D, Brox AC, et al. Acute-onset floaters and flashes: is this patient at risk for retinal detachment? JAMA. 2009 Nov 25;302(20):2243-9.[Abstract]
19. Prisco D, Marcucci R. Retinal vein thrombosis: risk factors, pathogenesis and therapeutic approach. Pathophysiol Haemost Thromb. 2002 Sep-Dec;32(5-6):308-11.[Abstract][Full Text]
20. Wong TY, Klein R. Retinal arteriolar emboli: epidemiology and risk of stroke. Curr Opin Ophthalmol. 2002 Jun;13(3):142-6.[Abstract]
21. Bora NS, Kaplan HJ. Intraocular diseases: anterior uveitis. Chem Immunol Allergy. 2007;92:213-20.[Abstract]
22. Desapriya E, Harjee R, Brubacher J, et al. Vision screening of older drivers for preventing road traffic injuries and fatalities. Cochrane Database Syst Rev. 2014 Feb 21;(2):CD006252.[Abstract][Full Text]
23. US Preventive Services Task Force. Screening for impaired visual acuity in older adults: US Preventive Services Task Force recommendation statement. JAMA. 2022 Jun 7;327(21):2123-8.[Abstract][Full Text]
24. Song P, Xu Y, Zha M, et al. Global epidemiology of retinal vein occlusion: a systematic review and meta-analysis of prevalence, incidence, and risk factors. J Glob Health. 2019 Jun;9(1):010427.[Abstract][Full Text]
25. The Royal College of Ophthalmologists. Retinal vein occlusion (RVO) guidelines. Feb 2022 [internet publication].[Full Text]
26. Flaxel CJ, Adelman RA, Bailey ST, et al. Retinal vein occlusions preferred practice pattern. Ophthalmology. 2020 Feb;127(2):288-320.[Abstract][Full Text]
27. Walker L, King M. This month's guideline: visual loss secondary to cosmetic filler injection. J Clin Aesthet Dermatol. 2018 May;11(5):E53-5.[Abstract][Full Text]
28. Newman NJ, Scherer R, Langenberg P, et al. The fellow eye in NAION: report from the ischemic optic neuropathy decompression trial follow-up study. Am J Ophthalmol. 2002 Sep;134(3):317-28.[Abstract]
29. Bird AC, Bressler NM, Bressler SB, et al. An international classification and grading system for age-related maculopathy and age-related macular degeneration. Surv Ophthalmol. 1995 Mar-Apr;39(5):367-74.[Abstract]
30. Cavallini GM, Masini C, Volante V, et al. Visual recovery after scleral buckling for macula-off retinal detachments: an optical coherence tomography study. Eur J Ophthalmol. 2007 Sep-Oct;17(5):790-6.[Abstract]
31. Mac Grory B, Lavin P, Kirshner H, et al. Thrombolytic therapy for acute central retinal artery occlusion. Stroke. 2020 Feb;51(2):687-95.[Abstract][Full Text]
32. Schmidt-Erfurth U, Garcia-Arumi J, Gerendas BS, et al. Guidelines for the management of retinal vein occlusion by the European Society of Retina Specialists (EURETINA). Ophthalmologica. 2019;242(3):123-62.[Abstract][Full Text]
33. Muthukumar N, Rossette D, Soundaram M, et al. Blindness following pituitary apoplexy: Timing of surgery and neuro-ophthalmic outcome. J Clin Neurosci. 2008 Aug;15(8):873-9.[Abstract]
34. Semple PL, Jane JA, Lopes MB, et al. Pituitary apoplexy: correlation between magnetic resonance imaging and histopathological results. J Neurosurg. 2008 May;108(5):909-15.[Abstract]
35. Dasgupta B; Giant Cell Arteritis Guideline Development Group. Concise guidance: diagnosis and management of giant cell arteritis. Clin Med (Lond). 2010 Aug;10(4):381-6.[Abstract]
36. Powers WJ, Rabinstein AA, Ackerson T, et al. Guidelines for the early management of patients with acute ischemic stroke: 2019 update to the 2018 guidelines for the early management of acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2019 Dec;50(12):e344-418.[Abstract][Full Text]
37. Schmidt GW, Broman AT, Hindman HB, et al. Vision survival after open globe injury predicted by classification and regression tree analysis. Ophthalmology. 2008 Jan;115(1):202-9.[Abstract]
38. Kanoff JM, Turalba AV, Andreoli MT, et al. Characteristics and outcomes of work-related open globe injuries. Am J Ophthalmol. 2010 Aug;150(2):265-9.[Abstract]
39. Loong SC. The eye in neurology: evaluation of sudden visual loss and diplopia--diagnostic pointers and pitfalls. Ann Acad Med Singapore. 2001 Mar;30(2):143-7.[Abstract]
40. American Society of Anesthesiologists. Practice advisory for perioperative visual loss associated with spine surgery 2019: an updated report by the American Society of Anesthesiologists Task Force on Perioperative Visual Loss, the North American Neuro-Ophthalmology Society, and the Society for Neuroscience in Anesthesiology and Critical Care. Anesthesiology. 2019 Jan;130(1):12-30.[Abstract][Full Text]
41. Michaelides M, Stover NB, Francis PJ, et al. Retinal toxicity associated with hydroxychloroquine and chloroquine: risk factors, screening, and progression despite cessation of therapy. Arch Ophthalmol. 2011 Jan;129(1):30-9.[Abstract][Full Text]
42. Melles RB, Marmor MF. The risk of toxic retinopathy in patients on long-term hydroxychloroquine therapy. JAMA Ophthalmol. 2014 Dec;132(12):1453-60.[Abstract][Full Text]
43. Flahavan EM, Li H, Gupte-Singh K, et al. Prospective case-crossover study investigating the possible association between nonarteritic anterior ischemic optic neuropathy and phosphodiesterase type 5 inhibitor exposure. Urology. 2017 Jul;105:76-84.[Abstract]
44. Campbell UB, Walker AM, Gaffney M, et al. Acute nonarteritic anterior ischemic optic neuropathy and exposure to phosphodiesterase type 5 inhibitors. J Sex Med. 2015 Jan;12(1):139-51.[Abstract]
45. Liu B, Zhu L, Zhong J, et al. The association between phosphodiesterase type 5 inhibitor use and risk of non-arteritic anterior ischemic optic neuropathy: a systematic review and meta-analysis. Sex Med. 2018 Sep;6(3):185-92.[Abstract][Full Text]
46. Purvin V, Kawasaki A, Borruat FX. Optic neuropathy in patients using amiodarone. Arch Ophthalmol. 2006 May;124(5):696-701.[Abstract][Full Text]
47. Pandit RJ, Gales K, Griffiths PG. Effectiveness of testing visual fields by confrontation. Lancet. 2001 Oct 20;358(9290):1339-40.[Abstract]
48. Donahue SP, Baker CN; American Academy of Pediatrics; American Association of Certified Orthoptists; American Association for Pediatric Ophthalmology and Strabismus; American Academy of Ophthalmology. Procedures for the evaluation of the visual system by pediatricians. Pediatrics. 2016 Jan;137(1). (Reaffirmed Feb 2022).[Abstract][Full Text]
49. Xie JS, Donaldson L, Margolin E. Papilledema: a review of etiology, pathophysiology, diagnosis, and management. Surv Ophthalmol. 2022 Jul-Aug;67(4):1135-59.[Abstract]
50. Bargiela D, Chinnery PF. Mitochondria in neuroinflammation - multiple sclerosis (MS), leber hereditary optic neuropathy (LHON) and LHON-MS. Neurosci Lett. 2019 Sep 25;710:132932.[Abstract][Full Text]
51. Gedde SJ, Chen PP, Muir KW, et al. Primary angle-closure disease preferred practice pattern®. Ophthalmology. 2021 Jan;128(1):P30-70.[Abstract][Full Text]
52. Flaxel CJ, Adelman RA, Bailey ST, et al. Posterior vitreous detachment, retinal breaks, and lattice degeneration Preferred Practice Pattern®. Ophthalmology. 2020 Jan;127(1):P146-81.[Abstract][Full Text]
53. Flaxel CJ, Adelman RA, Bailey ST, et al. Retinal and ophthalmic artery occlusions Preferred Practice Pattern®. Ophthalmology. 2020 Feb;127(2):P259-87.[Abstract][Full Text]
54. Hellmich B, Agueda A, Monti S, et al. 2018 Update of the EULAR recommendations for the management of large vessel vasculitis. Ann Rheum Dis. 2020 Jan;79(1):19-30.[Abstract][Full Text]
55. Mackie SL, Dejaco C, Appenzeller S, et al. British Society for Rheumatology guideline on diagnosis and treatment of giant cell arteritis. Rheumatology (Oxford). 2020 Mar 1;59(3):e1-23.[Abstract][Full Text]
56. Mollan SP, Paemeleire K, Versijpt J, et al. European Headache Federation recommendations for neurologists managing giant cell arteritis. J Headache Pain. 2020 Mar 17;21(1):28.[Abstract][Full Text]
57. Dejaco C, Ramiro S, Bond M, et al. EULAR recommendations for the use of imaging in large vessel vasculitis in clinical practice: 2023 update. Ann Rheum Dis. 2023 Aug 7.[Abstract][Full Text]
58. Maz M, Chung SA, Abril A, et al. 2021 American College of Rheumatology/Vasculitis Foundation guideline for the management of giant cell arteritis and takayasu arteritis. Arthritis Rheumatol. 2021 Aug;73(8):1349-65.[Abstract][Full Text]
59. Ponte C, Grayson PC, Robson JC, et al. 2022 American College of Rheumatology/EULAR classification criteria for giant cell arteritis. Ann Rheum Dis. 2022 Dec;81(12):1647-53.[Abstract][Full Text]
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