HyperHEP B

Adult Dosing .

Dosage forms:  INJ

hepatitis B infection prophylaxis, post-exposure

[blood exposure]

Dose: 0.06 mL/kg/dose IM x1; Start: within 24h of exposure if possible; Info: may give up to 7 days after exposure; give with HBV vaccine series if unvaccinated; may give with HBV vaccine booster dose if previously vaccinated; repeat dose in 1mo for patients who refuse HBV vaccine or are nonresponders to vaccine

[sexual exposure]

Dose: 0.06 mL/kg/dose IM x1; Start: within 14 days of exposure; Info: give with HBV vaccine series

[household exposure]

Dose: 0.06 mL/kg/dose IM x1; Start: within 14 days of exposure; Info: for patients with identifiable blood exposure to individuals with acute HBV infection; give with HBV vaccine series

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  INJ

hepatitis B infection prophylaxis, post-exposure

[blood exposure]

Dose: 0.06 mL/kg/dose IM x1; Start: within 24h of exposure if possible; Info: may give up to 7 days after exposure; give with HBV vaccine series if unvaccinated; may give with HBV vaccine booster dose if previously vaccinated; repeat dose in 1mo for patients who refuse HBV vaccine or are nonresponders to vaccine

[perinatal exposure]

Dose: 0.5 mL IM x1; Start: within 12h or birth; Info: for newborns with HbsAg-positive gestational parent, or HBsAg status unknown gestational parent if wt <2 kg; may give up to 7 days after birth if HBsAg-unknown gestational parent tests positive; give with HBV vaccine series

[household exposure, patients <12 mo]

Dose: 0.5 mL IM x1; Info: for patients whose primary caregiver has acute HBV infection; give with HBV vaccine series

[household exposure, patients 12 mo and older]

Dose: 0.06 mL/kg/dose IM x1; Start: within 14 days of exposure; Info: for patients with identifiable blood exposure to individuals with acute HBV infection; give with HBV vaccine series

[sexual exposure]

Dose: 0.06 mL/kg/dose IM x1; Start: within 14 days of exposure; Info: give with HBV vaccine series

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]