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Sunlenca
lenacapavir
Adult Dosing .
Dosage forms: TAB: 300 mg; INJ: various
HIV infection
- [2-day initiation regimen]
- Dose: 927 mg SC q6mo; Start: 927 mg SC x1 and 600 mg PO x1 on Day 1, then 600 mg PO x1 on Day 2; Info: for heavily tx-experienced patients with multi-drug resistant virus; may give injection up to 2wk before or after scheduled dose; see pkg insert for missed dose recommendations
- [15-day initiation regimen]
- Dose: 927 mg SC q6mo; Start: 600 mg PO qd on Day 1 and Day 2, then 300 mg PO x1 on Day 8, then 927 mg SC x1 on Day 15; Info: for heavily tx-experienced patients with multi-drug resistant virus; may give injection up to 2wk before or after scheduled dose; see pkg insert for missed dose recommendations
renal dosing
- [see below]
- CrCl >15: no adjustment; CrCl <15: not defined
- HD/PD: not defined
hepatic dosing
- [see below]
- Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.