Rytelo

Adult Dosing .

Dosage forms:  INJ

Special Note

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for uses, premeds, prophylactic antimicrobials, and dosing incl. toxicity-related dose adjustments

myelodysplastic syndrome, low or intermediate-1 risk

[7.1 mg/kg/dose IV q4wk]

Info: for pts w/ transfusion-dependent anemia relapsed or refractory to or ineligible for ESA tx requiring 4 or more RBC units over 8wk; D/C if no decr. in RBC transfusion burden after 24wk

renal dosing

[see below]

CrCl >30: no adjustment; CrCl <30: not defined

HD/PD: not defined

hepatic dosing

[see below]

bilirubin 1.1-3x ULN or AST >ULN: no adjustment; bilirubin >3x ULN: not defined

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.