Zevtera

Adult Dosing .

Dosage forms:  INJ

bacteremia, staphylococcal

[667 mg IV q8h for up to 42 days total]

Start: 667 mg IV q6h x8 days

pneumonia, community-acquired

[667 mg IV q8h x5-14 days]

skin/skin structure infections, acute bacterial

[667 mg IV q8h x5-14 days]

renal dosing

[bacteremia, staphylococcal]

CrCl >150: 667 mg q6h; CrCl 50-150: 667 mg q8h, start 667 mg q6h x8 days; CrCl 30-49: 667 mg q12h, start 667 mg q8h x8 days; CrCl 15-29: 333 mg q12h, start 333 mg q8h x8 days; CrCl <15: 333 mg q24h

HD: 333 mg q24h, on dialysis days admin. after dialysis; consider supplement if next maint. dose not due right after dialysis; PD: not defined

[all other indications]

CrCl >150: 667 mg q6h; CrCl 50-150: 667 mg q8h; CrCl 30-49: 667 mg q12h; CrCl 15-29: 333 mg q12h; CrCl <15: 333 mg q24h

HD: 333 mg q24h, on dialysis days admin. after dialysis; consider supplement if next maint. dose not due right after dialysis; PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  INJ

pneumonia, community-acquired

[3 mo-11 yo]

Dose: 20 mg/kg/dose IV q8h x7-14 days; Max: 667 mg/dose

[12 yo and older]

Dose: 13.3 mg/kg/dose IV q8h x7-14 days; Max: 667 mg/dose

renal dosing

[3 mo-1 yo]

renal impairment: not defined

HD/PD: not defined

[2-5 yo]

eGFR: 30-49: 13.3 mg/kg/dose q12h, max 667 mg/dose; eGFR 15-29: 13.3 mg/kg/dose q24h, max 333 mg/dose; eGFR <15: not defined

HD/PD: not defined

[6-11 yo]

eGFR: 30-49: 10 mg/kg/dose q12h, max 667 mg/dose; eGFR 15-29: 10 mg/kg/dose q24h, max 333 mg/dose; eGFR <15: not defined

HD/PD: not defined

[12 yo and older]

eGFR: 30-49: 10 mg/kg/dose q12h, max 667 mg/dose; eGFR 15-29: 10 mg/kg/dose q12h, max 333 mg/dose; eGFR <15: not defined

HD/PD: not defined

hepatic dosing

[not defined]