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Relexxii
methylphenidate
Black Box Warnings .
Abuse, Misuse, and Addiction
CNS stimulants have high potential for abuse and misuse, can lead to substance use disorder, incl. addiction; misuse and abuse can result in overdose and death, risk incr. w/ higher doses or unapproved admin. methods; assess risk for abuse, misuse, and addiction before prescribing and throughout tx; educate pts and families about risks and proper drug storage and disposal; monitor frequently for s/sx of abuse, misuse, and addiction during tx
Adult Dosing .
Dosage forms: ER TAB: 18 mg, 27 mg, 36 mg, 45 mg, 54 mg, 63 mg, 72 mg
Special Note
- [strength clarification]
- Info: all strengths expressed as methylphenidate hydrochloride
- [formulation clarification]
- Info: methylphenidate ER products not interchangeable; do not substitute on a mg to mg basis
ADHD
- [18-65 yo]
- Dose: 18-72 mg PO qam; Start: 18-36 mg PO qam, may incr. by 18 mg/day q7 days; Max: 72 mg/day; Info: duration 12h; do not cut/crush/chew tab; see pkg insert for conversion from IR form
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
- Dosage forms: ER TAB: 18 mg, 27 mg, 36 mg, 45 mg, 54 mg, 63 mg, 72 mg
Special Note
- [strength clarification]
- Info: all strengths expressed as methylphenidate hydrochloride
- [formulation clarification]
- Info: methylphenidate ER products not interchangeable; do not substitute on a mg to mg basis
ADHD
- [6-12 yo]
- Dose: 18-54 mg PO qam; Start: 18 mg PO qam, may incr. by 18 mg/day q7 days; Max: 54 mg/day; Info: duration 12h; do not cut/crush/chew tab; see pkg insert for conversion from IR form
- [13-17 yo]
- Dose: 18-72 mg PO qam; Start: 18 mg PO qam, may incr. by 18 mg/day q7 days; Max: 2 mg/kg/day up to 72 mg/day; Info: duration 12h; do not cut/crush/chew tab; see pkg insert for conversion from IR form
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]