Crenessity

Adult Dosing .

Dosage forms:  CAP: 25 mg, 50 mg, 100 mg; SOLUTION: 50 mg per mL

classic congenital adrenal hyperplasia, adjunct tx

[100 mg PO bid]

Info: give with glucocorticoid; may adjust glucocorticoid dose beginning 4wk after tx start based on androstenedione levels; give with meals

renal dosing

[see below]

eGFR >44: no adjustment; eGFR <44: not defined

HD/PD: not defined

hepatic dosing

[no adjustment]

Peds Dosing .

Dosage forms:  CAP: 25 mg, 50 mg, 100 mg; SOLUTION: 50 mg per mL

classic congenital adrenal hyperplasia, adjunct tx

[4 yo and older, 10-19 kg]

Dose: 25 mg PO bid; Info: give with glucocorticoid; may adjust glucocorticoid dose beginning 4wk after tx start based on androstenedione levels; give with meals

[4 yo and older, 20-54 kg]

Dose: 50 mg PO bid; Info: give with glucocorticoid; may adjust glucocorticoid dose beginning 4wk after tx start based on androstenedione levels; give with meals

[4 yo and older, >55 kg]

Dose: 100 mg PO bid; Info: give with glucocorticoid; may adjust glucocorticoid dose beginning 4wk after tx start based on androstenedione levels; give with meals

renal dosing

[see below]

eGFR >44: no adjustment; eGFR <44: not defined

HD/PD: not defined

hepatic dosing

[no adjustment]