Emrelis (telisotuzumab vedotin-tllv)

Adult Dosing .

Dosage forms:  INJ

Special Note

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing including toxicity-related dose adjustments

[dosing clarification]

for patients >100 kg, cap wt at 100 kg for dose calculations

nonsquamous non-small cell lung CA, locally advanced or metastatic

[1.9 mg/kg/dose IV q2wk]

Max: 190 mg/dose; Info: for patients with high c-Met protein overexpression

renal dosing

[see below]

CrCl >30: no adjustment; CrCl <30: not defined

HD/PD: not defined

hepatic dosing

[see below]

bilirubin 1.1-1.5x ULN or AST >ULN: no adjustment; bilirubin >1.5x ULN: not defined

Peds Dosing .

Peds dosing is currently unavailable or not applicable for this drug.