Doptelet Sprinkle

Adult Dosing .

Adult dosing is currently unavailable or not applicable for this drug.

Peds Dosing .

Dosage forms:  SPRINKLE CAP: 10 mg

Special Note

[equivalency or interchangeability info]

Info: Doptelet Sprinkle not interchangeable w/ Doptelet; do not substitute on a mg to mg basis

immune thrombocytopenia, persistent or chronic

[1-5 yo]

Dose: 10-20 mg po qd; Start: 10 mg PO qd; Max: 20 mg qd; Info: for patients w/ insufficient response to prior tx; see pkg insert for dose adjustments based on Plt response; use lowest effective dose to achieve/maintain Plt >50,000; D/C if Plt <50,000 after 4wk at max dose or Plt >400,000 after 2wk at 10 mg qwk; give w/ food; must open cap, but do not crush/chew granules

renal dosing

[see below]

CrCl >30: no adjustment; CrCl <30: not defined

HD/PD: not defined

hepatic dosing

[no adjustment]