Quiofic

Adult Dosing .

Dosage forms:  SOLUTION: 0.2 mg per mL

Special Note

[strength clarification]

Info: doses expressed as folic acid; 1 mg PO folic acid = 1.67 mg Dietary Folate Equivalent (DFE) if taken with food or 2 mg DFE if taken on empty stomach

megaloblastic anemia, folate deficiency-associated

[0.4 mg PO qd]

Start: up to 1 mg PO qd until hematologic correction; Info: incr. usual dose to 0.8 mg PO qd in pregnant or breastfeeding patients; consider incr. usual dose if alcoholism, hemolytic anemia, or chronic infection; doses >1 mg/day rarely more effective

dietary supplementation

[individualize dose]

Info: see Dietary Reference Intakes: Vitamin B9 (folic acid) table

neural tube defect prevention (off-label)

[0.4 mg PO qd]

Start: at least 1mo before conception; Info: for patients of childbearing potential; continue through 12 wk gestation; give 4 mg PO qd if high risk of neural tube defect

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]

Peds Dosing .

Dosage forms:  SOLUTION: 0.2 mg per mL

Special Note

[strength clarification]

Info: doses expressed as folic acid; 1 mg PO folic acid = 1.67 mg Dietary Folate Equivalent (DFE) if taken with food or 2 mg DFE if taken on empty stomach

megaloblastic anemia, folate deficiency-associated

[<2 yo]

Dose: 0.1 mg PO qd; Start: up to 1 mg PO qd until hematologic correction; Info: consider incr. usual dose if alcoholism, hemolytic anemia, or chronic infection; doses >1 mg/day rarely more effective

[2-3 yo]

Dose: up to 0.3 mg PO qd; Start: up to 1 mg PO qd until hematologic correction; Info: consider incr. usual dose if alcoholism, hemolytic anemia, or chronic infection; doses >1 mg/day rarely more effective

[4 yo and older]

Dose: 0.4 mg PO qd; Start: up to 1 mg PO qd until hematologic correction; Info: consider incr. usual dose if alcoholism, hemolytic anemia, or chronic infection; doses >1 mg/day rarely more effective

dietary supplementation

[individualize dose]

Info: see Dietary Reference Intakes: Vitamin B9 (folic acid) table

neural tube defect prevention (off-label)

[0.4 mg PO qd]

Start: at least 1mo before conception; Info: for patients of childbearing potential; continue through 12 wk gestation; give 4 mg PO qd if high risk of neural tube defect

renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

hepatic dosing

[not defined]